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Vol. 25 No. 11 (2013): Vol 25 Issue 11

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Phenylethanoids from the Root of Rosa rugosa and their Biological Activities

https://doi.org/10.14233/ajchem.2013.14219A
Yinke Li
Yunnan Academy of Tobacco Agricultural Science, Yuxi 653100, P.R. China ; Collge of Resource and Environment, Yuxi Normal University, Yuxi 653100, P.R. China
Jingjing Ma
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Liying Yang
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Lidang Shu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Yanqiong Shen
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Qiufen Hu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Zhangyuan Xia
Yunnan Academy of Tobacco Agricultural Science, Yuxi 653100, P.R. China

Asian Journal of Chemistry, Vol. 25 No. 11 (2013): Vol 25 Issue 11

Abstract

A new phenylethanoids, rugethanoid C (1), together with five known phenylethanoids (2-6), were isolated from the roots of Rosa rugosa. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. rugethanoid C (1) was tested for their anti HIV-1 activities and cytotoxicities. The results showed that rugethanoid C (1) has moderate potential cytotoxic ability and anti HIV-1 bioactivities.

Keywords

Rosa rugosa Phenylethanoids Anti HIV-1 activity Cytotoxic ability
Li, Y., Ma, J., Yang, L., Shu, L., Shen, Y., Hu, Q., & Xia, Z. (2013). Phenylethanoids from the Root of Rosa rugosa and their Biological Activities. Asian Journal of Chemistry, 25(11), 6457–6458. https://doi.org/10.14233/ajchem.2013.14219A
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