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Vol. 28 No. 5 (2016): Vol 28 Issue 5

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in vitro Evaluation of Few Indigenously Known Herbal Plants for their Anthelmintic Property

https://doi.org/10.14233/ajchem.2016.19562
Chander Mohan
Toxicology Laboratory, Division of Animal Nutrition and Feed Technology, ICAR-Central Institute for Research on Buffaloes, Hisar-125 001, India; Indira Gandhi National Open University, New Delhi-110 068, India
N. Saxena
Toxicology Laboratory, Division of Animal Nutrition and Feed Technology, ICAR-Central Institute for Research on Buffaloes, Hisar-125 001, India
B.I. Fozdar
Indira Gandhi National Open University, New Delhi-110 068, India
Rajender Kumar
ICAR-National Research Centre on Equines, Hisar-125 001, India
M.L. Sharma
Toxicology Laboratory, Division of Animal Nutrition and Feed Technology, ICAR-Central Institute for Research on Buffaloes, Hisar-125 001, India
V. Mudgal
Toxicology Laboratory, Division of Animal Nutrition and Feed Technology, ICAR-Central Institute for Research on Buffaloes, Hisar-125 001, India
Avijit Dey
Toxicology Laboratory, Division of Animal Nutrition and Feed Technology, ICAR-Central Institute for Research on Buffaloes, Hisar-125 001, India
B.S. Punia
Toxicology Laboratory, Division of Animal Nutrition and Feed Technology, ICAR-Central Institute for Research on Buffaloes, Hisar-125 001, India

Corresponding Author(s) : Chander Mohan

chandmehra2003@gmail.com

Asian Journal of Chemistry, Vol. 28 No. 5 (2016): Vol 28 Issue 5

Abstract

The messy use of anthelmintics leads to the establishment of parasitic resistance. Thus present study was designed to determine anthelmintic activity of some indigenously known angiospermic plants. Four plants were selected according to their local availability in Hisar (Haryana, India). Extracts in four different solvents were prepared from each plant and were evaluated qualitatively for the presence of phytochemical constituents. In vitro anthelmintic activity of each plant extracts were evaluated against Haemonchus contortus by larval motility assay method. Mortality of L3 larvae were recorded from a concentration range of 1 mg/mL to 400 mg/mL. Mean mortality was found to be highest for chloroform methanol extract (ranged from 55.81 to 82.56 % at the highest concentration level). Efficacy of albandazole (anthelmintic drug), a positive control was 65.21 % at 400 mg/mL which is comparable to efficacy of few plant extracts. Thus, it may be concluded that plant parts used in the present study may work as effective substitute of commonly used anthelmintic drugs.

Keywords

Gastrointestinal Physico-chemical properties in vitro model Albizia Anthelmintic Embelia Nyctanthes Solanum
Mohan, C., Saxena, N., Fozdar, B., Kumar, R., Sharma, M., Mudgal, V., … Punia, B. (2016). in vitro Evaluation of Few Indigenously Known Herbal Plants for their Anthelmintic Property. Asian Journal of Chemistry, 28(5), 1001–1003. https://doi.org/10.14233/ajchem.2016.19562
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