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Vol. 25 No. 10 (2013): Vol 25 Issue 10

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In Vitro Antioxidant and Anticancer Activities of the Extract from Paper Mulberry (Broussonetia papyrifera L.) Fruit

https://doi.org/10.14233/ajchem.2013.14594
Yang Li
School of Life Sciences, Northwestern Polytechnical University, Xi'an, P.R. China
Hailiang Li
School of Life Sciences, Northwestern Polytechnical University, Xi'an, P.R. China
Yuan Zhang
School of Life Sciences, Northwestern Polytechnical University, Xi'an, P.R. China
Lin Li
School of Life Sciences, Northwestern Polytechnical University, Xi'an, P.R. China
Chuanguang Qin
School of Life Sciences, Northwestern Polytechnical University, Xi'an, P.R. China ; Key Laboratory on Space Applied Physics and Chemistry of Ministry of Education; Key Laboratory on Macromolecular Science & Technology of Shaanxi Province; Department of Applied Chemistry, School of Natural and Applied Sciences, Northwestern Poly technical University, Xi’an 710129, P. R. China.

Corresponding Author(s) : Chuanguang Qin

qinchg@nwpu.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 10 (2013): Vol 25 Issue 10

Abstract

The antioxidant and anticancer activities of ethanolic extract of paper mulberry (Broussonetia papyrifera L.) fruit were investigated in this study. The total phenolic content of the extract was found to be 148.79 ± 0.91 mg gallic acid equivalents g-1 of lyophilized extract. The extract showed reducing power and was a scavenger of DPPH radicals. The extract inhibited the proliferation of human osteosarcoma MG63 cells, which associated with apoptosis and cell cycle arrest. The antioxidant and anticancer activities of the extract showed a dose-dependent increase in the assays. These studies demonstrated that the ethanolic extract of paper mulberry fruit is a potent antioxidant and exerts promising anticancer activity.

Keywords

Antioxidant activity Anticancer activity Phenolic compound Paper mulberry fruit Broussonetia papyrifera L
Li, Y., Li, H., Zhang, Y., Li, L., & Qin, C. (2013). In Vitro Antioxidant and Anticancer Activities of the Extract from Paper Mulberry (Broussonetia papyrifera L.) Fruit. Asian Journal of Chemistry, 25(10), 5453–5456. https://doi.org/10.14233/ajchem.2013.14594
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