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Vol. 25 No. 8 (2013): Vol 25 Issue 8

Copyright (c) 2013 AJC

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A Rapid Assay of Mezlocillin Sodium by Flow-Injection Chemiluminescence Detection

https://doi.org/10.14233/ajchem.2013.13950
Rui-Qiang Wang
First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China
Peng-Li Tao
Department of Chemistry, Zhengzhou University, Zhengzhou 450001, P.R. China
Rui Wang
Department of Chemistry, Zhengzhou University, Zhengzhou 450001, P.R. China
Yi Wang
First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China
Juan-Juan Pu
First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China
Xiao-Gai Wang
Department of Chemistry, Zhengzhou University, Zhengzhou 450001, P.R. China
Huan-Jing Dou
Department of Chemistry, Zhengzhou University, Zhengzhou 450001, P.R. China
Rui-Yong Wang
Department of Chemistry, Zhengzhou University, Zhengzhou 450001, P.R. China

Corresponding Author(s) : Rui-Qiang Wang

wangruiqiang@zzu.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 8 (2013): Vol 25 Issue 8

Abstract

A new chemiluminescence method coupled with the flow injection technique for the determination of mezlocillin sodium was developed. It was based on the enhancement of mezlocillin sodium on the chemiluminescence reaction of luminol with potassium ferricyanide in alkaline medium. Under the optimum conditions, the linear range for mezlocillin sodium was from 2.0 × 10-7 to 5.0 × 10-5 g mL-1 and the limit of detection was 6.8 × 10-9 g mL-1. The relative standard deviation (n = 11) was 0.31 % for 8.0 × 10-6 g mL-1 mezlocillin sodium. The proposed method was applied successfully to the determination of mezlocillin sodium for injection with satisfactory results.

Keywords

Chemiluminescence Flow-injection Ceftezole sodium Luminol
Wang, R.-Q., Tao, P.-L., Wang, R., Wang, Y., Pu, J.-J., Wang, X.-G., … Wang, R.-Y. (2013). A Rapid Assay of Mezlocillin Sodium by Flow-Injection Chemiluminescence Detection. Asian Journal of Chemistry, 25(8), 4301–4304. https://doi.org/10.14233/ajchem.2013.13950
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