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Vol. 25 No. 7 (2013): Vol 25 Issue 7

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Study on the Structure-Activity Relations of Brominated Hydroxy Diphenyl Ethers Derivatives with Anilines

https://doi.org/10.14233/ajchem.2013.13823
Bin Luo
Faculty of Chemistry, Sichuan University, Chengdu 610065, P.R. China
Hua-Hong Zhou
Department of Pathogenic Biology, School of Biomedical Science, Chengdu Medical College, Chengdu 610083, P.R. China
Kang-Kang Yu
Faculty of Chemistry, Sichuan University, Chengdu 610065, P.R. China
Kai-Qun Wu
Faculty of Chemistry, Sichuan University, Chengdu 610065, P.R. China
Tian Chen
Department of Pathogenic Biology, School of Biomedical Science, Chengdu Medical College, Chengdu 610083, P.R. China
Yu-Liang Wang
Faculty of Chemistry, Sichuan University, Chengdu 610065, P.R. China

Corresponding Author(s) : Kai-Qun Wu

wukaiqun@tom.com

Asian Journal of Chemistry, Vol. 25 No. 7 (2013): Vol 25 Issue 7

Abstract

In order to study the influence of anilines on antibacterial activity, eight novel brominated hydroxy diphenyl ethers derivatives were designed and synthesized. The antibacterial activities of the new compounds were tested via agar-well diffusion method in vitro under different concentrations. The results showed the derivatives had antibacterial activities at the concentration 50 μg/mL against Staphylococcus aureus SC and Staphylococcus aureus ATCC26112.

Keywords

Brominated hydroxy diphenyl ethers Structure-activity Anilines Antibacterial activity
Luo, B., Zhou, H.-H., Yu, K.-K., Wu, K.-Q., Chen, T., & Wang, Y.-L. (2013). Study on the Structure-Activity Relations of Brominated Hydroxy Diphenyl Ethers Derivatives with Anilines. Asian Journal of Chemistry, 25(7), 3863–3866. https://doi.org/10.14233/ajchem.2013.13823
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