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This work is licensed under a Creative Commons Attribution 4.0 International License.
Biological Activities of Herbaceous Peony Flower Extracts
Corresponding Author(s) : Jun Tao
Asian Journal of Chemistry,
Vol. 25 No. 7 (2013): Vol 25 Issue 7
Abstract
Herbaceous peony (Paeonia lactiflora Pall.) root is an important Traditional Chinese Medicine. To determine if the flower has any beneficial properties, we investigated antioxidant, antiinflammatory and anti a-glucosidase activities of petroleum ether, ethyl ether, ethyl acetate, n-butanol and water extracts of herbaceous peony flower. Antioxidant activity was evaluated by measuring total phenolic content, total antioxidant activity and DPPH radical scavenging activities. The ethyl ether and ethyl acetate extracts exhibited higher antioxidant ability than the other extracts. Moreover, the ethyl ether and ethyl acetate extracts had greater antiinflammatory activity on murine macrophage cells (RAW264.7). On the other hand, the petroleum ether extract and ethyl acetate extract showed strong inhibitory effect on a-glucosidase. These results suggest that flower from Herbaceous peony may have health-enhancing effects.
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- A. Braca, P.V. Kiem, P.H. Yen, N.X. Nhiem, T.H. Quang, N.X. Cuong and C.V. Minh, Fitoterapia, 79, 117 (2008).
- N. Kim, K.R. Park, I.S. Park and Y.H. Park, Food Chem., 96, 496 (2006).
- H.B. Wang, W.F. Gu, W.J. Chu, S. Zhang, X.C. Tang and G.W. Qin, J. Nat. Prod., 72, 1321 (2009).
- A. Ikuta, K. Kamiya, T. Satake and Y. Saiki, Phytochemistry, 38, 1203 (1995).
- K. Kamiya, K. Yoshioka, Y. Saiki, A. Ikuta and T. Satake, Phytochemistry, 44, 141 (1997).
- N. Jia, Q.Y. Shu, L.S. Wang, H. Du, Y.J. Xu and Z.A. Liu, Sci. Hortic., 117, 167 (2008).
- H.J. Kim, E.J. Chang, S.J. Bae, S.M. Shim, H.D. Park, C.H. Rhee, J.H. Park and S.W. Choi, Arch. Pharm. Res., 25, 293 (2002).
- N. Kumar and M.G. Motto, Phytochemistry, 25, 250 (1985).
- D. Guo, G. Ye and H. Guo, Fitoterapia, 77, 613 (2006).
- S.C. Lee, Y.S. Kwon, K.H. Son, H.P. Kim and M.Y. Heo, Arch. Pharm. Res., 28, 775 (2005).
- F. Chen, H.T. Lu and Y. Jiang, J. Chromatogr. A, 1040, 205 (2004).
- B. Lee, Y.W. Shin, E.A. Bae, S.J. Han, J.S. Kim, S.S. Kang and D.H. Kim, Arch. Pharm. Res., 31, 445 (2008).
- L. Xiao, Y.Z. Wang, J. Liu, X.T. Luo, Y. Ye and X.Z. Zhu, Life Sci., 784, 413 (2005).
- Y. Yang, T. Yu, H.J. Jang, S.E. Byeon, S.Y. Song, B.H. Lee, M.H. Rhee, T.W. Kim, J. Lee, S. Hong and J.Y. Cho, J. Ethnopharmacol., 139, 616 (2012).
- P. McCue, Y.I. Kwon and M.K. Shetty, Asia Pacific J. Clin. Nutri., 14, 145 (2005).
- T.L. Shale, W.A. Stirk and J. Staden, J. Ethnopharmacol., 67, 347 (1999).
- R.R. Baumgartner, D. Steinmann, E.H. Heiss,A.G. Atanasov, M. Ganzera, H. Stuppner and V.M. Dirsch, Nat. Prod., 73, 1578 (2010).
- M.J. Jung, S.I. Heo and M.H. Wang, Food Chem., 108, 482 (2008).
- P. Prieto, M. Pineda and M. Aguilar, Anal. Biochem., 269, 337 (1999).
- S. Kilani, R.B. Ammar, I. Bouhlel,A. Abdelwahed, N. Hayder, A. Mahmoud, K. Ghedira and L. Chekir-Ghedira, Environ. Toxicol. Pharmacol., 20, 478 (2005).
- W. Hu, T. Shen and M.H. Wang, J. Food Sci. Nutr., 14, 277 (2009).
- Y.M. Kim, M.H. Wang and H.I. Rhee, Carbohydr. Res., 339, 715 (2004).
- J.Y. Cho, K.U. Baik, J.H. Jung and M.H. Park, Eur. J. Pharmacol., 398, 399 (2000).
- D.B. Choi, S.S. Park, J.L. Ding and W.S. Cha, Biotechonol. Bioprocess Eng., 12, 516 (2007).
- D. Steinberg, J. Internal. Med., 233, 227 (1993).
- K. Shimada, K. Fujikawa, K. Yahara and T. Nakamura, J. Agric. Food Chem., 40, 945 (1997).
- E.R. Stadtman and R.L. Levin, Ann. NY Acad. Sci., 899, 191 (2000).
- L. Ferrero-Miliani, O.H. Nielsen, P.S. Andersen and S.E. Girardin, Clin. Exp. Immunol., 147, 227 (2007).
- P.O. Osadebe and F.B.C. Okoye, J. Ethnopharmacol., 89, 19 (2003).
- C. Nicholas, S. Batra, M.A. Vargo, O.H. Voss, M.A. Gavrilin, M.D. Wewers, D.C. Guttridge, E. Grotewold and A.I. Doseff, J. Immunol., 179, 7121 (2007).
- S.E. Inzucchi, J. Am. Med. Assoc., 287, 360 (2002).
References
A. Braca, P.V. Kiem, P.H. Yen, N.X. Nhiem, T.H. Quang, N.X. Cuong and C.V. Minh, Fitoterapia, 79, 117 (2008).
N. Kim, K.R. Park, I.S. Park and Y.H. Park, Food Chem., 96, 496 (2006).
H.B. Wang, W.F. Gu, W.J. Chu, S. Zhang, X.C. Tang and G.W. Qin, J. Nat. Prod., 72, 1321 (2009).
A. Ikuta, K. Kamiya, T. Satake and Y. Saiki, Phytochemistry, 38, 1203 (1995).
K. Kamiya, K. Yoshioka, Y. Saiki, A. Ikuta and T. Satake, Phytochemistry, 44, 141 (1997).
N. Jia, Q.Y. Shu, L.S. Wang, H. Du, Y.J. Xu and Z.A. Liu, Sci. Hortic., 117, 167 (2008).
H.J. Kim, E.J. Chang, S.J. Bae, S.M. Shim, H.D. Park, C.H. Rhee, J.H. Park and S.W. Choi, Arch. Pharm. Res., 25, 293 (2002).
N. Kumar and M.G. Motto, Phytochemistry, 25, 250 (1985).
D. Guo, G. Ye and H. Guo, Fitoterapia, 77, 613 (2006).
S.C. Lee, Y.S. Kwon, K.H. Son, H.P. Kim and M.Y. Heo, Arch. Pharm. Res., 28, 775 (2005).
F. Chen, H.T. Lu and Y. Jiang, J. Chromatogr. A, 1040, 205 (2004).
B. Lee, Y.W. Shin, E.A. Bae, S.J. Han, J.S. Kim, S.S. Kang and D.H. Kim, Arch. Pharm. Res., 31, 445 (2008).
L. Xiao, Y.Z. Wang, J. Liu, X.T. Luo, Y. Ye and X.Z. Zhu, Life Sci., 784, 413 (2005).
Y. Yang, T. Yu, H.J. Jang, S.E. Byeon, S.Y. Song, B.H. Lee, M.H. Rhee, T.W. Kim, J. Lee, S. Hong and J.Y. Cho, J. Ethnopharmacol., 139, 616 (2012).
P. McCue, Y.I. Kwon and M.K. Shetty, Asia Pacific J. Clin. Nutri., 14, 145 (2005).
T.L. Shale, W.A. Stirk and J. Staden, J. Ethnopharmacol., 67, 347 (1999).
R.R. Baumgartner, D. Steinmann, E.H. Heiss,A.G. Atanasov, M. Ganzera, H. Stuppner and V.M. Dirsch, Nat. Prod., 73, 1578 (2010).
M.J. Jung, S.I. Heo and M.H. Wang, Food Chem., 108, 482 (2008).
P. Prieto, M. Pineda and M. Aguilar, Anal. Biochem., 269, 337 (1999).
S. Kilani, R.B. Ammar, I. Bouhlel,A. Abdelwahed, N. Hayder, A. Mahmoud, K. Ghedira and L. Chekir-Ghedira, Environ. Toxicol. Pharmacol., 20, 478 (2005).
W. Hu, T. Shen and M.H. Wang, J. Food Sci. Nutr., 14, 277 (2009).
Y.M. Kim, M.H. Wang and H.I. Rhee, Carbohydr. Res., 339, 715 (2004).
J.Y. Cho, K.U. Baik, J.H. Jung and M.H. Park, Eur. J. Pharmacol., 398, 399 (2000).
D.B. Choi, S.S. Park, J.L. Ding and W.S. Cha, Biotechonol. Bioprocess Eng., 12, 516 (2007).
D. Steinberg, J. Internal. Med., 233, 227 (1993).
K. Shimada, K. Fujikawa, K. Yahara and T. Nakamura, J. Agric. Food Chem., 40, 945 (1997).
E.R. Stadtman and R.L. Levin, Ann. NY Acad. Sci., 899, 191 (2000).
L. Ferrero-Miliani, O.H. Nielsen, P.S. Andersen and S.E. Girardin, Clin. Exp. Immunol., 147, 227 (2007).
P.O. Osadebe and F.B.C. Okoye, J. Ethnopharmacol., 89, 19 (2003).
C. Nicholas, S. Batra, M.A. Vargo, O.H. Voss, M.A. Gavrilin, M.D. Wewers, D.C. Guttridge, E. Grotewold and A.I. Doseff, J. Immunol., 179, 7121 (2007).
S.E. Inzucchi, J. Am. Med. Assoc., 287, 360 (2002).