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Vol. 25 No. 7 (2013): Vol 25 Issue 7

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Synthesis, Characterization, Crystal Structure and Interaction with DNA of Cobalt(II) Complex

https://doi.org/10.14233/ajchem.2013.13678A
Wei-Ji Hu
Xingzhi College, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, P.R. China
Quan-Yin Guan
Xingzhi College, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, P.R. China
Guo-Liang Zhao
Xingzhi College, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, P.R. China

Corresponding Author(s) : Guo-Liang Zhao

sky53@zjnu.cn

Asian Journal of Chemistry, Vol. 25 No. 7 (2013): Vol 25 Issue 7

Abstract

A cobalt(II) complex with the composition [Co(DMAP)2(bipy)(H2O)2] (HDMAP = 3,4-dimethoxyphenyl acetic acid, bipy = 4,4'-bipyridine), was synthesized under hydrothermal conditions from CoSO4·7H2O and 3,4-dimethoxyphenyl acetic acid together with 4,4'-bipyridine and characterized by IR spectra and thermal behaviour. The crystal structure of the complex was determined by X-ray crystallography. It crystallizes in the monoclinic system, space group C2/c with a = 2.57437(9) nm, b = 1.14108(4) nm, c = 0.98716(3) nm, b = 92.683(2)º, V = 2.89667(17) nm3, Z = 4. In addition, the interaction of the complex with DNA was also investigated via the ethidium bromide fluorescence displacement experiments by detecting the fluorescence intensity of the complex-EB-DNA mixture. CCDC: 859086.

Keywords

Cobalt(II) complex Crystal structure DNA binding 3,4-Dimethoxyphenylacetic acid 4,4'-Bipyridine
Hu, W.-J., Guan, Q.-Y., & Zhao, G.-L. (2013). Synthesis, Characterization, Crystal Structure and Interaction with DNA of Cobalt(II) Complex. Asian Journal of Chemistry, 25(7), 3617–3620. https://doi.org/10.14233/ajchem.2013.13678A
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