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In Vitro Antioxidant Activity of Various Extracts of Ginger (Zingiber officinale L.) Seed
Corresponding Author(s) : Yesim Yesiloglu
Asian Journal of Chemistry,
Vol. 25 No. 7 (2013): Vol 25 Issue 7
Abstract
The methanolic and ethanolic extracts from ginger (Zingiber officinale L.) seed (ZOS) were investigated for their antioxidant and radical scavenging activities in eight different assays, namely, total antioxidant activity, reducing power, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, total flavonoid content, total phenolic compound and metal chelating activities. Both methanolic extract and ethanolic extract of Zingiber officinale L. seed exhibited strong total antioxidant activity. These various antioxidant activities were compared with synthetic antioxidants such as butylated hydroxyanisole, butylated hydroxytoluene, Trolox, a-tocopherol and ascorbic acid. The methanol extract of Zingiber officinale L. seed exhibited greater antioxidant capacity than that of ethanol.
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- E. Czinner, K. Hagymasi, A. Blazovics, A. Kery, E. Szoke and E. Lemberkovics, J. Ethnopharmacol., 77, 31 (2001).
- I.S. Young and J.V. Woodside, J. Clin. Pathol., 54, 176 (2001).
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- M.E. Narhaizan, S.H. Fong, I. Arnin and L.Y. Chew, Food Chem., 122, 1055 (2010).
- S.C. Liu, J.T. Lin, C.K. Wang, H.Y. Chen and D.J. Yang, Food Chem., 114, 577 (2009).
- P.K. Saxena, Trends Food Sci. Technol., 20, 596 (2009).
- A.A. Shati and F.G. Elsaid, Food Chem. Toxicol., 47, 1945 (2009).
- M. Mueller, S. Hobiger and A. Jungbaver, Food Chem., 122, 987 (2010).
- E.G. Mejia, M.V. Ramirez-Mares and S. Puangpraphant, Brain Behav. Immun., 23, 721 (2009).
- M. Khader, N. Bresgen and P.M. Eckl, J. Ethnopharmacol., 127, 319 (2010).
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- E.W.C. Chan, Y.Y. Lim, L.F. Wong, S. Lianto, S.K. Wong, K.K. Lim, C.E. Joe and T.Y. Lim, Food Chem., 109, 477 (2008).
- H. Mitsuda, K. Yuasumoto and K. Iwami, Eiyo to Shokury, 19, 210 (1996).
- M. Oyaizu, Japan. J. Nutr., 44, 307 (1986).
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- K. Shimada, K. Fujikawa, K. Yahara and T. Nakamura, J. Agric. Food Chem., 40, 945 (1992).
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- R.J. Ruch, S.J. Cheng and J.F. Klaunig, Carcinogenesis, 10, 1003 (1989).
- K. Slinkard and V.L. Singleton, Am. J. Enol. Viticult., 28, 49 (1977).
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- S. Meir, J. Kanner, B. Akin and S.P. Hadas, J. Agric. Food Chem., 43, 1813 (1995).
- J.R. Soares, T.C.P. Dins, A.P. Cunha and L.M. Ameida, Free Radic. Res., 26, 469 (1997).
- P.D. Duh, Y.Y. Tu and G.C. Yen, Lebens. Wissen. Technol., 32, 269 (1999).
- F. Yamaguchi, T. Ariga, Y. Yoshimira and H. Nakazawa, J. Agric. Food Chem., 48, 180 (2000).
- B. Halliwell, In eds.: O.I. Aruoma and B. Halliwell: The Biological Toxicity of Free Radicals and Other Reactive Species, Free Radicals and Food Additives, London: Taylor and Francis (1991).
- B. Halliwell and J.M.C. Gutteridge, Free Radical in Biology and Medicine, Oxford University Press, Oxford, UK (1985).
- M. Wettasinghe and F. Shahidi, Food Chem., 70, 17 (2000).
- T. Hatano, R. Edamatsu, A. Mori, Y. Fujita and E. Yasuhara, Chem. Pharm. Bull., 37, 2016 (1980).
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- M.B. Ningappa, R. Dinesha and L. Srinivas, Food Chem., 106, 720 (2007).
- W. Aneta, O. Jan and C. Renata, Food Chem., 105, 940 (2007).
- R. Manian, N. Anusuya, P. Siddhuraju and S. Manian, Food Chem., 107, 1000 (2008).
- F. Sharififiar, G. Dehgn-Nudeh and M. Mirtajaldini, Food Chem., 112, 885 (2009).
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References
E. Czinner, K. Hagymasi, A. Blazovics, A. Kery, E. Szoke and E. Lemberkovics, J. Ethnopharmacol., 77, 31 (2001).
I.S. Young and J.V. Woodside, J. Clin. Pathol., 54, 176 (2001).
Y.S. Velioglu, G. Mazza, L. Gao and B.D. Oomah, J. Agric. Food Chem., 46, 4113 (1998).
M.E. Narhaizan, S.H. Fong, I. Arnin and L.Y. Chew, Food Chem., 122, 1055 (2010).
S.C. Liu, J.T. Lin, C.K. Wang, H.Y. Chen and D.J. Yang, Food Chem., 114, 577 (2009).
P.K. Saxena, Trends Food Sci. Technol., 20, 596 (2009).
A.A. Shati and F.G. Elsaid, Food Chem. Toxicol., 47, 1945 (2009).
M. Mueller, S. Hobiger and A. Jungbaver, Food Chem., 122, 987 (2010).
E.G. Mejia, M.V. Ramirez-Mares and S. Puangpraphant, Brain Behav. Immun., 23, 721 (2009).
M. Khader, N. Bresgen and P.M. Eckl, J. Ethnopharmacol., 127, 319 (2010).
I.-M. Chung, M. Ali and A. Ahmad, Asian J. Chem., 17, 1915 (2005); I.-M. Chung, N. Praveen, S.-J. Kim and A. Ahmad, Asian J. Chem., 24, 831 (2012).
E.W.C. Chan, Y.Y. Lim, L.F. Wong, S. Lianto, S.K. Wong, K.K. Lim, C.E. Joe and T.Y. Lim, Food Chem., 109, 477 (2008).
H. Mitsuda, K. Yuasumoto and K. Iwami, Eiyo to Shokury, 19, 210 (1996).
M. Oyaizu, Japan. J. Nutr., 44, 307 (1986).
Q. Liu, G. Zhu and P. Huang, Zhongguo Zhong Yao Za Zhi, 161, 50 (1991).
K. Shimada, K. Fujikawa, K. Yahara and T. Nakamura, J. Agric. Food Chem., 40, 945 (1992).
T.C.P. Dinis, V.M.C. Madeira and L.M. Almeida, Arch. Biochem. Biophys., 315, 161 (1994).
R.J. Ruch, S.J. Cheng and J.F. Klaunig, Carcinogenesis, 10, 1003 (1989).
K. Slinkard and V.L. Singleton, Am. J. Enol. Viticult., 28, 49 (1977).
J. Wang, X. Yuan, Z. Jin, Y. Tian and H. Song, Food Chem., 104, 242 (2007).
S. Meir, J. Kanner, B. Akin and S.P. Hadas, J. Agric. Food Chem., 43, 1813 (1995).
J.R. Soares, T.C.P. Dins, A.P. Cunha and L.M. Ameida, Free Radic. Res., 26, 469 (1997).
P.D. Duh, Y.Y. Tu and G.C. Yen, Lebens. Wissen. Technol., 32, 269 (1999).
F. Yamaguchi, T. Ariga, Y. Yoshimira and H. Nakazawa, J. Agric. Food Chem., 48, 180 (2000).
B. Halliwell, In eds.: O.I. Aruoma and B. Halliwell: The Biological Toxicity of Free Radicals and Other Reactive Species, Free Radicals and Food Additives, London: Taylor and Francis (1991).
B. Halliwell and J.M.C. Gutteridge, Free Radical in Biology and Medicine, Oxford University Press, Oxford, UK (1985).
M. Wettasinghe and F. Shahidi, Food Chem., 70, 17 (2000).
T. Hatano, R. Edamatsu, A. Mori, Y. Fujita and E. Yasuhara, Chem. Pharm. Bull., 37, 2016 (1980).
X. Gao, M. Ohlander, N. Jeppsson, L. Bjork and V. Trajkovski, J. Agric. Food Chem., 48, 1485 (2000).
M. Tanaka, C.W. Kuei, Y. Nagashima and T. Taguchi, Nippon Suisan Gakkaishi, 54, 1409 (1998).
M.B. Ningappa, R. Dinesha and L. Srinivas, Food Chem., 106, 720 (2007).
W. Aneta, O. Jan and C. Renata, Food Chem., 105, 940 (2007).
R. Manian, N. Anusuya, P. Siddhuraju and S. Manian, Food Chem., 107, 1000 (2008).
F. Sharififiar, G. Dehgn-Nudeh and M. Mirtajaldini, Food Chem., 112, 885 (2009).
S. Bahramikia, A. Ardestani and R. Yazdanparast, Food Chem., 115, 37 (2009).