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Alterations in Serum Biochemical Parameters of Horses with Leptospirosis
Corresponding Author(s) : S. Guzel
Asian Journal of Chemistry,
Vol. 25 No. 6 (2013): Vol 25 Issue 6
Abstract
In this study, the alterations in serum biochemical parameters of horses with leptospirosis was investigated. For this aim, 8 h with leptospirosis, were determined by the microscopic agglutination test and 8 healthy horses were used as material. The levels of serum glucose, urea, creatinine, uric acid, total cholesterol, high-density lipoprotein (HDL), triglyceride, total protein, albumin, globulin, aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), creatinine kinase (CK), sodium, potassium, chloride, calcium, phosphorus, magnesium were evaluated in leptospirosis cases and healty horses. Although we found significant decreases in levels of glucose (p < 0.01), uric acid (p < 0.01), HDL cholesterol (p < 0.05), ALP (p < 0.01), Cl (p < 0.01), Ca (p < 0.05), P (p < 0.001) in horses with leptospirosis, level of urea (p < 0.05) in horses with leptosprosis showed significant increases. The results obtained may suggest that these parameters might have taken part in the diagnosis and treatment of horse leptospirosis.
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- World Health Organization (WHO), Leptospirosis Worldwide, Weekly Epidemiological Record, pp. 74/237-74/242 (1999).
- O.M. Radostits, D.C. Blood and C.C. Gay, Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goats, Baillaire Tindall, London, UK, edn. 8, pp. 884-908 (1994).
- J.C. Thompson and B.W. Manktelow, J. Comp. Pathol., 101, 201 (1989).
- R. Plank and D. Dean, Microbes Infect., 2, 1265 (2000).
- A.V. Lomar, D. Diament and J.R. Torres, Infect. Dis. Clin. North Am., 14, 23 (2000).
- A.W. Kitson-Piggot and J.F. Prescott, Can. J. Vet. Res., 51, 448 (1987).
- P. Vijayachari, A.P. Sugunan and A.N. Shriram, J. Biosci., 33, 557 (2008).
- M. Pinna, G. Martins, I. Freire and W. Lilenbaum, Cienc. Rural., 40, 2214 (2010).
- S. Faine, World Health Organization (WHO), Guidelines for Control of Leptospirosis, Section B-38, Geneva (1982).
- E.F. Daher, D.M. Brunetta, G.B. Silva Junior, R.A. Puster, R.M.S.V. Patrocinio, Revista do Instituto de Medicina Tropical de Sao Paulo, 45, 307 (2003).
- H.M. Erdogan, M. Karapehlivan, M. Citil, O. Atakisi, E. Uzlu,A. Unver, Vet Res Commun., 32, 333 (2008).
- H. Begenik, Y.U. Soyoral, A.I. Baran, M.K. Karahocagil and R. Erkoç, Van Tip Dergisi, 18, 33 (2011).
- I.F. Gazi, F.A. Apostolou, E.N. Liberopoulos, T.D. Filippatos, C.C. Tellis, M.S. Elisaf and A.D. Tselepis, Lipids, 46, 953 (2011).
- C. Zaragoza, R. Barrera, F. Centeno, J.A. Tapia and M.C. Mane, J. Comp. Pathol., 129, 169 (2003).
References
World Health Organization (WHO), Leptospirosis Worldwide, Weekly Epidemiological Record, pp. 74/237-74/242 (1999).
O.M. Radostits, D.C. Blood and C.C. Gay, Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goats, Baillaire Tindall, London, UK, edn. 8, pp. 884-908 (1994).
J.C. Thompson and B.W. Manktelow, J. Comp. Pathol., 101, 201 (1989).
R. Plank and D. Dean, Microbes Infect., 2, 1265 (2000).
A.V. Lomar, D. Diament and J.R. Torres, Infect. Dis. Clin. North Am., 14, 23 (2000).
A.W. Kitson-Piggot and J.F. Prescott, Can. J. Vet. Res., 51, 448 (1987).
P. Vijayachari, A.P. Sugunan and A.N. Shriram, J. Biosci., 33, 557 (2008).
M. Pinna, G. Martins, I. Freire and W. Lilenbaum, Cienc. Rural., 40, 2214 (2010).
S. Faine, World Health Organization (WHO), Guidelines for Control of Leptospirosis, Section B-38, Geneva (1982).
E.F. Daher, D.M. Brunetta, G.B. Silva Junior, R.A. Puster, R.M.S.V. Patrocinio, Revista do Instituto de Medicina Tropical de Sao Paulo, 45, 307 (2003).
H.M. Erdogan, M. Karapehlivan, M. Citil, O. Atakisi, E. Uzlu,A. Unver, Vet Res Commun., 32, 333 (2008).
H. Begenik, Y.U. Soyoral, A.I. Baran, M.K. Karahocagil and R. Erkoç, Van Tip Dergisi, 18, 33 (2011).
I.F. Gazi, F.A. Apostolou, E.N. Liberopoulos, T.D. Filippatos, C.C. Tellis, M.S. Elisaf and A.D. Tselepis, Lipids, 46, 953 (2011).
C. Zaragoza, R. Barrera, F. Centeno, J.A. Tapia and M.C. Mane, J. Comp. Pathol., 129, 169 (2003).