Issue

Vol. 25 No. 6 (2013): Vol 25 Issue 6

Copyright (c) 2013 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Free Radical Scavenging Activity of Leucas indica Flowers and Leaves

https://doi.org/10.14233/ajchem.2013.13694
A. Vinayagam
Department of Chemistry, Sathyabama University, Chennai-600 119, India
P.N. Sudha
Department of Chemistry, DKM College for Women (Autonomous), Vellore-632 001, India

Corresponding Author(s) : P.N. Sudha

parsu8@yahoo.com

Asian Journal of Chemistry, Vol. 25 No. 6 (2013): Vol 25 Issue 6

Abstract

Present work was undertaken to study antioxidant free radical scavenging activity of leaves and flowers extracts of Leucas indica. Crude methanolic extracts was screened for in vitro antioxidant free radical scavenging activity by diphenyl picryl hydrazyl, nitric oxide radical scavenging and superoxide radical scavenging assay methods. Results showed that IC50 value of methanol extracts of leaves in diphenyl picryl hydrazyl, nitric oxide scavenging and superoxide radical scavenging assays are 241.11, 282.97 and 250.45 μg/mL. Similarly IC50 value of methanol extracts of flowers in diphenyl picryl hydrazyl, nitric oxide scavenging and superoxide radical scavenging assays are 0.19, 2.05 and 2.15 μg/mL, respectively. Phytochemical screening revealed that flavonoids, alkaloids and phenolic compound are present in methanol extracts of leaves and flowers and may be responsible for the antioxidant activity. The result showed that Leucas indica flowers are more potential free radical scavenging activity than leaves.

Keywords

Leucas indica Diphenyl picryl hydrazyl Nitric oxide Superoxide radical scavenging assay
Vinayagam, A., & Sudha, P. (2013). Free Radical Scavenging Activity of Leucas indica Flowers and Leaves. Asian Journal of Chemistry, 25(6), 3349–3352. https://doi.org/10.14233/ajchem.2013.13694
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. K.M. Reddy, S. Viswanathan, D. Thirugnanasabmantham, R. Santa and K. Lalitha, Fitoterapia, 64, 151 (1993).
  2. J.M. McCord, N. Engl. J. Med., 312, 159 (1985).
  3. M. Valko, D. Leibfritz, J. Moncol, M.T.D. Cronin, M. Mazur and J. Telser, Int. J. Biochem. Cell. Biol., 39, 44 (2006).
  4. O.A. Olukemi, I.O. Olukemi, M.O. Sofidiya, O.A. Aniunoh, B.M. Lawal and I.O. Tade, Electr. J. Environ. Agric. Food Chem., 496, 1086 (2005).
  5. N. Delanty and Ma. Dichter, Arch. Neurol., 57, 1265 (2000).
  6. J. Pokorny, Trends Food Sci. Tech., 2, 223 (1991).
  7. S.E. Atawodi, Afr. J. Biotech., 4, 128 (2005).
  8. C.A. Rice-Evans, N.J. Miller, P.G. Bolwell, P.M. BramLey and J.B. Pridham, Free Radical. Res., 23, 375 (1995).
  9. M.P. Kähkönen, A.I. Hopia, H.J. Vuorela, J.P. Rauha, K. Pihlaja and T.S. Kujala, J. Agric. Food. Chem., 47, 3954 (1999).
  10. D.K. Pal, S. Kumar, P. Chakraborty and M.A. Kumar, J. Nat. Remeady, 8, 160 (2008).
  11. R.M. Dhenge, P.P. Katolkar, S.L. Bhongade and P.R. Itankar, Int. J. Pharmacol. Biol. Sci., 2, 37 (2008).
  12. M. Payá, M.L. Ferrándiz, F. Miralles, C. Montesinos, A. Ubeda and M.J. Alcaraz, Arzneim-Forsch. Drug Res., 43, 655 (1993).
  13. V. Ponti, M.U. Dianzani, K. Cheeseman and T.F. Slater, Chemico-Biol. Interact., 23, 281 (1978).
  14. G. Yen and H. Chen, J. Agric. Food. Chem., 43, 7 (1995).
  15. A. Parr and G.P. Bolwell, J. Sci. Food. Agric., 80, 985 (2000).
  16. C. Vijaya, M. Ramanathan, T. Subburaju and B. Suresh, Indian Drugs, 3, 453 (2002).
  17. S.B. Datir, S.A. Nirmal, A.B. Ganjare, S.B. Bhawar and M.J. Patil, Res. J. Pharmacognosy Phytochem., 1, 220 (2009).
  18. S.H. Nam and M.Y. Kang, Pharm. Biol., 42, 409 (2004).
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 2 Download : 1