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Synthesis and Antimicrobial Activity of Some Phenophosphazines
Corresponding Author(s) : Snehal Lokhandwala
Asian Journal of Chemistry,
Vol. 25 No. 3 (2013): Vol 25 Issue 3
Abstract
A new family of organophosphorus compounds namely 3-chloro-1-(10-hydroxy-10-oxo-5,10-dihydro-phenophosphazin-2-yl)-4-(substituted phenyl)-azetidin-2-one (3a-j) has been synthesized by reaction of 2-[(substituted benzylidene)-amino]-10-oxo-5,10-dihydro-phenophosphazin-10-ol (2a-j) with chloro acetyl chloride and triethyl amine. All these compounds were characterized by elemental and spectral analysis. Their antimicrobial activity was also evaluated.
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References
P.G. Sergeev and D.G. Kudrayashov, J. Gen. Chem., 8, 266 (1938).
V.M. Harings, Helv. Chim. Acta, 43, 1826 (1960).
R.N. Jenkins and L.D. Freedman, J. Org. Chem., 40/6, 766 (1975).
A. Kanazawa and T. Ikeda, Coord. Chem. Rev., 198, 117 (2000).
S. Giri and M.H. Khan, J. Indian Chem. Soc., 71, 201 (1994).
K.R. Desai, H.D. Patel and B.D. Mistry, Orient. J. Chem., 19, 245 (2003).
A. Kumar, M. Tyagi and V.K. Srivastava, Indian J. Chem., 42B, 214 (2003).
S.D. Sharma, A. Saluja and S. Bhadhuri, Indian J. Chem., 39B, 156 (2000).
K.R. Desai and K.M. Mistry, Indian J. Chem., 44B, 1452 (2005).
K.R. Desai and K.M. Mistry, E-J Chem., 4, 189 (2004)