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Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey
Corresponding Author(s) : Ismet Uysal
Asian Journal of Chemistry,
Vol. 25 No. 2 (2013): Vol 25 Issue 2
Abstract
The antimicrobial activity of the ethanol, acetone, ethyl acetate and chloroform extracts from Centaurea persica Boiss., C. polyclada DC. and C. consanguinea DC. (Asteraceae) were investigated by agar-well diffusion assay. All of the extracts exhibited an antimicrobial effect against most of the bacteria and all of the yeasts tested. The plant extracts were also screened for radical scavenging potential using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) in vitro model system for antioxidant activity. Ethyl acetate extracts showed the most significant inhibitory activity. Therefore, the minimal inhibitory concentration (MIC) of only ethyl acetate extracts of the samples was determined and C. consanguinea showed the highest antimicrobial effect. However, the ethanol extract of C. polyclada at 0.5 mg/mL concentration displayed the highest antioxidant activity. This activity was followed by ethanol extracts of. C. persica, ethyl acetate extracts of C. polclada, C. persica and C. consanguinea respectively.
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References
M.M. Cowan, Clin. Microbiol. Rev., 12, 546 (1999).
J.N. Elof, J. Ethnopharmacol., 160, 1 (1998).
Y. Kumarasamy, M. Middleton, R.G. Reid, L. Nahar and S.D. Sarker, Fitoterapia, 74, 609 (2003).
I. Uysal, S. Celik and M. Oldacay, Pak. J. Biol. Sci., 8, 1812 (2005).
V. Vaajs, N. Todorovic, M. Ristic, V. Tesevic, B. Todorovic, P. Janackovic, P. Marin and S. Milosavlievic, Phytochemistry, 52, 383 (1999).
E. Yesilada, I. Gurbuz and H. Shibata, J. Ethnopharmacol., 66, 289 (1999).
H. Skaltsa, D. Lazari, C. Panagouleas, E. Georgiadou, B. Garcia and M. Sokovic, Phytochemistry, 52, 383 (2000).
A. Karioti, H. Skaltsa, D. Lazari, M. Sokovic and C.G. Harvala, Z. Naturforsch, 57c, 75 (2002).
Y. Kumarasamy, P.J. Cox, M. Jaspars, L. Nahar and S.D. Sarker, J. Ethnopharmacol., 83, 73 (2002).
E. K. Barbour, M.A. Sharif, V.K. Sagherian, A.N. Habre, R.S. Talhouk and S.N. Talhouk, J. Ethnopharmacol., 93, 1 (2004).
K. Guven, S. Celik and I. Uysal, Pharm. Biol., 43, 67 (2005).
N. Yayli, A. Yasar, C. Gulec, A. Usta, S. Kolayli, K. Coskuncelebi and S. Karaoglu, Phytochemistry, 66, 1741 (2005).
M.I. Skliar, M.S. Toribio and D.S. Oriani, Fitoterapia, 76, 737 (2005).
R. Arif, E. Kupeli and F. Ergun, J. Sci. Gazi Univ., 17, 149 (2004).
Y. Tekeli and M. Sezgin, Süleyman Demirel Univ. J. Faculty Sci. Art, 2, 204 (2007).
Y. Tekeli, M. Sezgin and M.A. Sanda, Süleyman Demirel Univ. J. Faculty Sci. Art, 3, 35 (2008).
Y. Tekeli, M. Sezgin and A. Aktümsek, Asian J. Chem., 20, 4831 (2008).
S.A. Dahanuka, R.A. Kulkarni and N.N. Rege, Indian J. Pharmacol., 32, 81 (2000).
C.M. Liyana-Pathirana and F. Shahidi, J. Sci. Food. Agric., 86, 477 (2006).
G. Wagenitz, In ed.: P.H. Davis, Centaurea L. Flora of Turkey and the East Aegean Islands, Edinburg University Press, Edinburgh, pp. 490- 556 (1975).
T. Ekim, M. Koyuncu, M. Vural, H. Duman, Z. Aytaç and N. Adigüzel, Red Data Book of Turkish Plants, Turkish Association for the Conservation of Nature and Van Centennial University Publishing (2000).
R. Rojas, B. Bustamante, J. Bauer, I. Fernandez, J. Alban and O. Lock, J. Ethnopharmacol., 88, 199 (2003).
F. Sahin, I. Karaman, M. Gulluce, H. Ögütçü, M. Sengül, A. Adigüzel and R. Kotan, J. Ethnopharmacol., 87, 61 (2003).
E.W. Koneman, S.D. Allen, W.M. Janda, P.C. Schreckenberger and W.C. Winn, Color Atlas and Textbook of Diagnostic Microbiology, Lippincott-Raven Publ, Philadelphia (1997).
J.R. Zgoda and J.R. Porter, Pharm. Biol., 39, 221 (2001).