Studies on Chemical Constituents of Twigs of Trichosanthes kirilowii Maxim

Wenjuan Duan; Shaobin Pan; Zongyuan Yu; Xiao Wang; Jia Li; Yongqing Zhang

doi:10.14233/ajchem.2015.18021

Issue

Vol. 27 No. 8 (2015): Vol 27 Issue 8

Issue Published : April 27, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

Studies on Chemical Constituents of Twigs of Trichosanthes kirilowii Maxim

https://doi.org/10.14233/ajchem.2015.18021

Wenjuan Duan

Shandong Analysis and Test Center, Shandong Academy of Sciences, Jinan 250014, P.R. China

Shaobin Pan

College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, P.R. China

Zongyuan Yu

Central Laboratory, Shandong Academy of Chinese Medicine, Jinan 250014, P.R. China

Xiao Wang

Shandong Analysis and Test Center, Shandong Academy of Sciences, Jinan 250014, P.R. China; College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, P.R. China

Jia Li

College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, P.R. China

Yongqing Zhang

College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, P.R. China

Corresponding Author(s) : Xiao Wang

wangx@sdas.org

Asian Journal of Chemistry, Vol. 27 No. 8 (2015): Vol 27 Issue 8
Article Published : April 27, 2015

Abstract

In the present study, 12 compounds were isolated from ethyl acetate extract of the twigs of Trichosanthes kirilowii Maxim.. Their structures were determined by UV, IR, EI-MS, ESI-MS, 1D and 2D NMR techniques. These compounds were identified as 4-[formyl-5-(methoxymethyl)-1H-pyrrol-1-yl]-butanoic acid (1), 3-hydroxy-1-(4-hydroxyphenyl)-1-propanone (2), p-hydroxybenzoic acid (3), 4-(2- formyl-5-hydroxymethylpyrrol-1-yl)-butyric acid (4), 2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]- propane-1,3-diol (5), 2-[4-(3-hydroxy-1-propenyl)-2-methoxyphenoxy]-1,3-propanediol (6), (-)-methyl dihydrophaseate (7), 4'-dihydrophaseic acid (8), 4-hydroxy-3-methyloxybenzoic acid (9), quercetin-3-O-rutinoside (10), salicylic acid (11), 2-methoxy-2-(4'-hydroxyphenyl)-ethanol (12). All of the compounds were isolated from the twigs of Trichosanthes kirilowii Maxim. for the first time. Compounds 1 to 9, 11 and 12 were firstly reported from the genus of Trichosanthes.

Keywords

Twigs of Trichosanthes kirilowii Maxim. Chemical constituents

Duan, W., Pan, S., Yu, Z., Wang, X., Li, J., & Zhang, Y. (2015). Studies on Chemical Constituents of Twigs of Trichosanthes kirilowii Maxim. Asian Journal of Chemistry, 27(8), 2756–2758. https://doi.org/10.14233/ajchem.2015.18021

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References

Chinese Pharmacopoeia Commission, Pharmacopoeia of People’s Republic of China, vol. 1, p. 104 (2010).
Y.R. Teng, L.X. Wang and Y.Q. Zhang, Qilu Pharm. Affairs, 29, 417 (2010).
S.S. Wang, Shanxi Med. J., 38, 67 (2009).
S. Zhou, Shandong Pharm. Ind., 21, 27 (2002).
J.H. Tu, J. Yu and W.G. Chen, Chin. Pharm., 7, 562 (2004).
J.M. Chao and J.M. Liu, Chin. Pharm. J., 31, 140 (1996).
J.M. Chao and B. He, Chin. J. Chin. Mater. Med., 24, 612 (1999).
Y.M. Chin, S.W. Lim, S.H. Kim, D.Y. Shin, Y.G. Suh, Y.B. Kim, Y.C. Kim and J. Kim, Bioorg. Med. Chem. Lett., 13, 79 (2003); doi:10.1016/S0960-894X(02)00846-6.
H.T. Le, D.T. Ha, C.T.A. Minh, T.H. Kim, P. Kiem, N.D. Thuan and M.K. Na, Arch. Pharm. Res., 35, 87 (2012); doi:10.1007/s12272-012-0110-2.
M.F. Wang, H. Kikuzaki, N.Q. Zhu, S.M. Sang, N. Nakatani and C.T. Ho, J. Agric. Food Chem., 48, 235 (2000); doi:10.1021/jf990761p.
S.M. Sang, A. Lao, Y.S. Wang, C.K. Chin, R.T. Rosen and C.T. Ho, J. Agric. Food Chem., 50, 6318 (2002); doi:10.1021/jf025651o.
S.F. Farag, Y. Kimura, H. Ito, J. Takayasu, H. Tokuda and T. Hatano, J. Nat. Med., 63, 91 (2009); doi:10.1007/s11418-008-0291-7.
L. Zhao, L.Z. Li, Y. Peng and S.J. Song, J. Shenyang Pharm. Univ., 29, 9 (2012).
R. Kraus and G. Spiteller, Biol. Mass Spectrom., 20, 53 (1991); doi:10.1002/bms.1200200203.
X.F. Li, X.R. Dai, Z. Dai, Y. Zhang, H. Liang and R.C. Lin, Chin. Tradit. Herbal Drugs, 43, 1685 (2012).
Z. Zhang, W. Zhang, Y.P. Ji, Y. Zhao, C.G. Wang and J.F. Hu, Phytochemistry, 71, 693 (2010); doi:10.1016/j.phytochem.2009.12.017.
W.S. Feng, B. Zhu, X.K. Zheng, X.K. Zheng, Y.L. Zhang, L.G. Yang and Y.J. Li, Chin. J. Nat. Med., 9, 108 (2011).
C.M. Li, T. Wang and Y. Zhang, J. Shenyang Pharm. Univ., 27, 803 (2010).
Y.L. Li, M.X. Su and Y.Z. Cen, J. Chin. Med. Mater, 29, 331 (2006).
Y. Wang, Y. Wang, G.C. Wang, X.Q. Zhang and W.C. Ye, Chin. J. Nat. Med., 5, 357 (2007).
T. Matsumura, T. Ishikawa and J. Kitajima, Phytochemistry, 61, 455 (2002); doi:10.1016/S0031-9422(02)00288-1.

References

Chinese Pharmacopoeia Commission, Pharmacopoeia of People’s Republic of China, vol. 1, p. 104 (2010).

Y.R. Teng, L.X. Wang and Y.Q. Zhang, Qilu Pharm. Affairs, 29, 417 (2010).

S.S. Wang, Shanxi Med. J., 38, 67 (2009).

S. Zhou, Shandong Pharm. Ind., 21, 27 (2002).

J.H. Tu, J. Yu and W.G. Chen, Chin. Pharm., 7, 562 (2004).

J.M. Chao and J.M. Liu, Chin. Pharm. J., 31, 140 (1996).

J.M. Chao and B. He, Chin. J. Chin. Mater. Med., 24, 612 (1999).

Y.M. Chin, S.W. Lim, S.H. Kim, D.Y. Shin, Y.G. Suh, Y.B. Kim, Y.C. Kim and J. Kim, Bioorg. Med. Chem. Lett., 13, 79 (2003); doi:10.1016/S0960-894X(02)00846-6.

H.T. Le, D.T. Ha, C.T.A. Minh, T.H. Kim, P. Kiem, N.D. Thuan and M.K. Na, Arch. Pharm. Res., 35, 87 (2012); doi:10.1007/s12272-012-0110-2.

M.F. Wang, H. Kikuzaki, N.Q. Zhu, S.M. Sang, N. Nakatani and C.T. Ho, J. Agric. Food Chem., 48, 235 (2000); doi:10.1021/jf990761p.

S.M. Sang, A. Lao, Y.S. Wang, C.K. Chin, R.T. Rosen and C.T. Ho, J. Agric. Food Chem., 50, 6318 (2002); doi:10.1021/jf025651o.

S.F. Farag, Y. Kimura, H. Ito, J. Takayasu, H. Tokuda and T. Hatano, J. Nat. Med., 63, 91 (2009); doi:10.1007/s11418-008-0291-7.

L. Zhao, L.Z. Li, Y. Peng and S.J. Song, J. Shenyang Pharm. Univ., 29, 9 (2012).

R. Kraus and G. Spiteller, Biol. Mass Spectrom., 20, 53 (1991); doi:10.1002/bms.1200200203.

X.F. Li, X.R. Dai, Z. Dai, Y. Zhang, H. Liang and R.C. Lin, Chin. Tradit. Herbal Drugs, 43, 1685 (2012).

Z. Zhang, W. Zhang, Y.P. Ji, Y. Zhao, C.G. Wang and J.F. Hu, Phytochemistry, 71, 693 (2010); doi:10.1016/j.phytochem.2009.12.017.

W.S. Feng, B. Zhu, X.K. Zheng, X.K. Zheng, Y.L. Zhang, L.G. Yang and Y.J. Li, Chin. J. Nat. Med., 9, 108 (2011).

C.M. Li, T. Wang and Y. Zhang, J. Shenyang Pharm. Univ., 27, 803 (2010).

Y.L. Li, M.X. Su and Y.Z. Cen, J. Chin. Med. Mater, 29, 331 (2006).

Y. Wang, Y. Wang, G.C. Wang, X.Q. Zhang and W.C. Ye, Chin. J. Nat. Med., 5, 357 (2007).

T. Matsumura, T. Ishikawa and J. Kitajima, Phytochemistry, 61, 455 (2002); doi:10.1016/S0031-9422(02)00288-1.

Issue

Vol. 27 No. 8 (2015): Vol 27 Issue 8

Studies on Chemical Constituents of Twigs of Trichosanthes kirilowii Maxim

Corresponding Author(s) : Xiao Wang

Abstract

Keywords

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