Synthesis and Activity of Novel Fungicide 2-(3-Chlorophenylcarbamoyl)phenyl Acetate

Chixiang Zhang; Zhou Wang; Bo Pu; Xuesong Wang; Shirong Jiao

doi:10.14233/ajchem.2015.17833

Issue

Vol. 27 No. 7 (2015): Vol 27 Issue 7, 2015

Issue Published : March 29, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

Synthesis and Activity of Novel Fungicide 2-(3-Chlorophenylcarbamoyl)phenyl Acetate

https://doi.org/10.14233/ajchem.2015.17833

Chixiang Zhang

School of Bioengineering, Xihua University, Chengdu 610039, P.R. China

Zhou Wang

School of Bioengineering, Xihua University, Chengdu 610039, P.R. China

Bo Pu

School of Bioengineering, Xihua University, Chengdu 610039, P.R. China

Xuesong Wang

School of Physics and Chemistry, Xihua University, Chengdu 610039, P.R. China

Shirong Jiao

School of Bioengineering, Xihua University, Chengdu 610039, P.R. China

Corresponding Author(s) : Shirong Jiao

15208372274@163.com

Asian Journal of Chemistry, Vol. 27 No. 7 (2015): Vol 27 Issue 7, 2015
Article Published : March 29, 2015

Abstract

In the present study, 2-(3-chlorophenylcarbamoyl)phenyl acetate was synthesized by the ammonolysis of 2-(chlorocarbonyl)phenyl acetate. Its structure was confirmed by IR and ¹H NMR. Its antifungal activity against Sclerotinia sclerotiorum and Helminthosprium maydis has been determined in the laboratory. The results showed that it had good antifungal activity against the two different pathogenic fungi of plants. Its median effective concentrations (EC₅₀) reached 2 and 3.80 mg L^-1, respectively.

Keywords

Antifungal activity 2-(3-Chlorophenylcarbamoyl)phenyl acetate

Zhang, C., Wang, Z., Pu, B., Wang, X., & Jiao, S. (2015). Synthesis and Activity of Novel Fungicide 2-(3-Chlorophenylcarbamoyl)phenyl Acetate. Asian Journal of Chemistry, 27(7), 2356–2358. https://doi.org/10.14233/ajchem.2015.17833

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References

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References

X.J. Chen, M.J. Cao, Y. Wang, Y.H. Tong and J.Y. Xu, Chin. J. Oil Crop Sci., 31, 503 (2009).

Y.L. Pan, Z.Y. Wang and H.Z. Wu, J. Jiangsu Agric., 13, 32 (1997).

Z.Q. Shi, M.G. Zhou and Z.Y. Ye, J. Jiangsu Agric., 16, 212 (2000).

W. Li, Y.J. Zhou and H.G. Chen, Chin. J. Oil Crop Sci., 29, 63 (2007).

K.Y. Liu and F.X. Chen, Anhui Agric. Sci., 35, 756 (2007).

D.G. Hutton, Australas. Plant Pathol., 17, 34 (1988); doi:10.1071/APP9880034.

Y.X. Qi, F.X. Chen and K.J. Ding, Pesticides, 8, 567 (2006).

FAO Plant Prot. Bull., 30, 30 (1982).

A. ten Have, R. van Berloo, P. Lindhout and J.A.L. van Kan, Eur. J. Plant Pathol., 113, 153 (2007); doi:10.1007/s10658-006-9081-9.

S.I. Ignatova, N.S. Gorshkova and T.A. Tereshonkova, Acta Physiol. Plant., 22, 326 (2000); doi:10.1007/s11738-000-0047-9.

H. Egashira, A. Kuwashima, H. Ishiguro, K. Fukushima, T. Kaya and S. Imanishi, Acta Physiol. Plant., 22, 324 (2000); doi:10.1007/s11738-000-0046-x.

R.L. Guimaraes, R.T. Chetelat and H.U. Stotz, Eur. J. Plant Pathol., 110, 13 (2004); doi:10.1023/B:EJPP.0000010133.62052.e4.

R. Finkers, P. Berg, R. Berloo, A. Have, A.W. Heusden, J.A.L. Kan and P. Lindhout, Theor. Appl. Genet., 114, 585 (2007); doi:10.1007/s00122-006-0458-0.

X. Wang, Med. Hypotheses, 50, 239 (1998); doi:10.1016/S0306-9877(98)90024-X.

D.W. Gilroy, Prostag. Leukotr. Ess., 73, 203 (2005); doi:10.1016/j.plefa.2005.05.007.

C. Millikan and N. Futrell, J. Stroke Cerebrovasc. Dis., 5, 248 (1995); doi:10.1016/S1052-3057(10)80199-5.

J.R. Vane, R.J. Flower and R.M. Botting, Stroke, 21(Suppl.), IV12 (1990).

M.L. Dyken, H.J.M. Barnett, J.D. Easton, W.S. Fields, V. Fuster, V. Hachinski, J.W. Norris and D.G. Sherman, Stroke, 23, 1395 (1992); doi:10.1161/01.STR.23.10.1395.

H. Tohgi, S. Konno, K. Tamura, B. Kimura and K. Kawano, Stroke, 23, 1400 (1992); doi:10.1161/01.STR.23.10.1400.

R.H. Ackerman and K.L. Newman, Ann. Neurol., 28, 224 (1990).

C.M. Helgason, K.L. Tortorice, S.R. Winkler, D.W. Penney, J.J. Schuler, T.J. McClelland and L.D. Brace, Stroke, 24, 345 (1993); doi:10.1161/01.STR.24.3.345.

W.K. Hass, J.D. Easton, H.P. Adams Jr., W. Pryse-Phillips, B.A. Molony, S. Anderson and B. Kamm, N. Engl. J. Med., 321, 501 (1989); doi:10.1056/NEJM198908243210804.

D.M. McCarthy, Best Pract. Res. Cl. Ga., 26, 101 (2012); doi:10.1016/j.bpg.2012.01.008.

W. Huang and G.F. Yang, Bioorg. Med. Chem., 14, 8280 (2006); doi:10.1016/j.bmc.2006.09.016.

Issue

Vol. 27 No. 7 (2015): Vol 27 Issue 7, 2015

Synthesis and Activity of Novel Fungicide 2-(3-Chlorophenylcarbamoyl)phenyl Acetate

Corresponding Author(s) : Shirong Jiao

Abstract

Keywords

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