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Vol. 27 No. 7 (2015): Vol 27 Issue 7, 2015

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Poly(aryl ether) Dendritic Structures Based on 1,4,8,11-Tetraazacyclotetradecane Core: Synthesis, Characterization, Photophysical Properties and Biological activity

https://doi.org/10.14233/ajchem.2015.18414
M. Dilek
Afyon Kocatepe University, Faculty of Engineering, Chemical Engineering Department, Afyonkarahisar, Turkey
O. Dilek Bayindir
Department of Chemistry, Afyon Kocatepe University, Afyonkarahisar, Turkey

Corresponding Author(s) : M. Dilek

mdilek@aku.edu.tr

Asian Journal of Chemistry, Vol. 27 No. 7 (2015): Vol 27 Issue 7, 2015

Abstract

This work describes the synthesis of two new dendrimers consisting of a 1,4,8,11-tetraazacyclotetradecane (cyclam) core appended with poly(aryl ether) dendritic structures carrying a donor (4-methyl-7-hydroxycoumarin) on the surface. Its structure was determined by 1H NMR, 13C NMR and elemental analysis. The photophysical properties of the series of poly(aryl ether) dendrimers have been determined and the effect of the generation number on the absorption and emission properties of the synthesized dendritic structures was investigated. As the chromophore group number on the surface of the dendritic structure increased, molar absorptivity coefficients and emission intensities of the structures were found to increase. The prepared dendritic structures were tested for their antimicrobial activity against, Salmonella typhimurium NRRLB, Micrococcus luteus, Pseudomonas aeruginosa, Enterococcus fecalis ATCC-29212, Bacillus cereus ATCC-117787, Klepsiella pneumonia, Bacillus subtilis NRS-744, Proteus vulgoris, Yersinia enterolitica and Saccharomyces cereviciae. Synthesized dendritic structures showed moderate activity against different strains of bacteria.

Keywords

Dendrimers Photophysics Absorption spectra 1 4 8 11-Tetraazacyclotetradecane Biological activity
Dilek, M., & Dilek Bayindir, O. (2015). Poly(aryl ether) Dendritic Structures Based on 1,4,8,11-Tetraazacyclotetradecane Core: Synthesis, Characterization, Photophysical Properties and Biological activity. Asian Journal of Chemistry, 27(7), 2587–2592. https://doi.org/10.14233/ajchem.2015.18414
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