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Microwave-Assisted Synthesis of New 6-Ureido-4-anilinoquinazoline Derivatives
Corresponding Author(s) : Yi Liu
Asian Journal of Chemistry,
Vol. 28 No. 1 (2016): Vol 28 Issue 1
Abstract
An efficient rapid method for the synthesis of new 6-ureido-4-anilinoquinazoline derivatives derived from 2-amino-5-nitrobenzoic acid under microwave irradiation has been developed. All of the new compounds were identified by 1H NMR, 13C NMR, IR, MS and elemental analyses.
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- D.J. Connolly, D. Cusack, T.P. O’Sullivan and P.J. Guiry, Tetrahedron, 61, 10153 (2005); doi:10.1016/j.tet.2005.07.010.
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- C.O. Kappe and D. Dallinger, Nat. Rev. Drug Discov., 5, 51 (2006); doi:10.1038/nrd1926.
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References
D.J. Connolly, D. Cusack, T.P. O’Sullivan and P.J. Guiry, Tetrahedron, 61, 10153 (2005); doi:10.1016/j.tet.2005.07.010.
A. Witt and J. Bergman, Curr. Org. Chem., 7, 659 (2003); doi:10.2174/1385272033486738.
W.L.F. Armarego, Adv. Heterocycl. Chem., 1, 253 (1963); doi:10.1016/S0065-2725(08).
S. Madapa, Z. Tusi, A. Mishra, K. Srivastava, S.K. Pandey, R.S. Tripathi, K. Puri and S. Batra, Bioorg. Med. Chem., 17, 222 (2009); doi:10.1016/j.bmc.2008.11.005.
B. Marvania, P.C. Lee, R. Chaniyara, H.J. Dong, S. Suman, R. Kakadiya, T. Chou, T.C. Lee, A. Shah and T.L. Su, Bioorg. Med. Chem., 19, 1987 (2011); doi:10.1016/j.bmc.2011.01.055.
W.S. Chow and T.H. Chan, Tetrahedron Lett., 50, 1286 (2009); doi:10.1016/j.tetlet.2008.12.119.
A. Rauf, S. Sharma and S. Gangal, ARKIVOC, 137 (2007); doi:10.3998/ark.5550190.0008.g15.
C.O. Kappe and D. Dallinger, Nat. Rev. Drug Discov., 5, 51 (2006); doi:10.1038/nrd1926.
W.D. Shipe, S.E. Wolkenberg and C.W. Lindsley, Drug Discov. Today. Technol., 2, 155 (2005); doi:10.1016/j.ddtec.2005.05.002.
H.A. Saad, M.M. Youssef and M.A. Mosselhi, Molecules, 16, 4937 (2011); doi:10.3390/molecules16064937.
J. Domarkas, F. Dudouit, C. Williams, Q. Qiyu, R. Banerjee, F. Brahimi and B.J. Jean-Claude, J. Med. Chem., 49, 3544 (2006); doi:10.1021/jm0600390.
M. Shaul, G. Abourbeh, O. Jacobson, Y. Rozen, D. Laky, A. Levitzki and E. Mishani, Bioorg. Med. Chem., 12, 3421 (2004); doi:10.1016/j.bmc.2004.04.044.