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Vol. 27 No. 6 (2015): Vol 27 Issue 6

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Synthesis, Structure and DNA-Binding Properties of Manganese(II) Complex with 1,3-bis(1-Benzylbenzimidazol-2-yl)-2-oxapropane

https://doi.org/10.14233/ajchem.2015.17663
Huilu Wu
School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, P.R. China
Yuchen Bai
School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, P.R. China
Furong Shi
School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, P.R. China
Mingchang Wu
School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, P.R. China
Zhen Li
School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, P.R. China
Yanhui Zhang
School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, P.R. China

Corresponding Author(s) : Huilu Wu

wuhuilu@163.com

Asian Journal of Chemistry, Vol. 27 No. 6 (2015): Vol 27 Issue 6

Abstract

A five-coordinated manganese(II) complex containing ligand 1,3-bis(1-benzylbenzimidazol-2-yl)-2-oxopropane (bobb), with composition Mn(bobb)(pic)2 (pic = picrate), has been synthesized and characterized. The crystal structure of complex has been determined by single-crystal X-ray diffraction. The manganese(II) complex adopts a distorted square-pyramidal geometry. In addition, DNA-binding properties of the ligand bobb and its manganese(II) complex have been investigated by electronic absorption and viscosity measurements. The experimental results suggest that ligand and manganese(II) complex bind to DNA via an intercalation binding mode and their binding affinity to DNA follows the order of manganese(II) complex greater than ligand bobb.

Keywords

1 3-bis(1-Benzylbenzimidazol-2-yl)-2-oxopropane Manganese(II) complex Crystal structure DNA-binding property
Wu, H., Bai, Y., Shi, F., Wu, M., Li, Z., & Zhang, Y. (2015). Synthesis, Structure and DNA-Binding Properties of Manganese(II) Complex with 1,3-bis(1-Benzylbenzimidazol-2-yl)-2-oxapropane. Asian Journal of Chemistry, 27(6), 2029–2032. https://doi.org/10.14233/ajchem.2015.17663
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