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Synthesis and Antifungal Potential of Co(II), Ni(II) and Cu(II) Chelates with Nitrogen, Oxygen and Sulphur Containing Schiff Bases
Corresponding Author(s) : B.K. Rai
Asian Journal of Chemistry,
Vol. 27 No. 6 (2015): Vol 27 Issue 6
Abstract
In the present article a series of complex of the type ML2 where M = Co(II), Ni(II) and Cu(II), L = 2-butyl-[3-hydroxy propyl)-3,1-(4H)-quinazoline semicarbazone/thiosemicarbozone have been synthesized. Their structures were confirmed by means of molar mass, elemental analyses, infrared spectra, electronic spectra, magnetic susceptibility and conductivity measurement. All the compounds were screened against species of plant pathogenic fungi using disc diffusion technique. It was observed on comparison with reference to fungicides, the complexes were found to be more effective than ligands,
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- A. Albert and G.B. Barlin, J. Chem. Soc., 3129 (1962); doi:10.1039/JR9620003129.
- M.M. Ghorab, S. El-Sayed Barakat, H.M. Saker and M.M. Abd Rabo, Arzneimitterlforschung, 56, 665 (2006); doi:10.1055/s-0031-1296769.
- E.M. Jessy and D. Vachala, Pharmacologyonline, 2, 618 (2008).
- V. Gupta, S.K. Kashaw, V. Jatav and P. Mishra, Med. Chem. Res., 17, 205 (2008); doi:10.1007/s00044-007-9054-3.
- M.S. Hamed, M.M. Kamel, M.M. Kassem, M.S. Nofal and F.M. Ahmed, Acta Poloniae Pharm.-Drug Res., 67, 159 (2010).
- A.M. Al-Obaid, S.G. Abdel-Hamide, H.A. El-Kashef, A.A.-M. Abdel-Aziz, A.S. El-Azab, H.A. Al-Khamees and H.I. El-Subbagh, Eur. J. Med. Chem., 44, 2379 (2009); doi:10.1016/j.ejmech.2008.09.015.
- M.A. Al-Omar, A.S. El-Azb, H.A. El-Obeid and S.G. Abdel Hamcide, J. Saudi Chem. Soc., 10, 113 (2006).
- A. Kumar, S. Sharma, K. Archana, K. Bajaj, S. Sharma, H. Panwar, T. Singh and V.K. Srivastava, Bioorg. Med. Chem., 11, 5293 (2003); doi:10.1016/S0968-0896(03)00501-7.
- C. Lu, J. Yang, J. Chinag, M. Hour, K. Lin, J. Lin, W. Huang, M. Tsuzuki, T. Leel and J. Chung, PlosOne, 7, 1 (2012).
- B.K. Rai, S.N. Vidyarthi, O.M. Prakash and A. Baluni, Orient J. Chem., 29, 801 (2013); doi:10.13005/ojc/290264.
- B.K. Rai, R. Singh, P. Anand, S.K. Singh and A. Amit, Orient J. Chem., 29, 753 (2013); doi:10.13005/ojc/290254; (b) B.K. Rai, R. Anand, Asian J. Chem., 25, 480 (2013); doi:10.14233/ajchem.2013.13199C.
- B.K. Rai, A. Thakur and Divya Asian J. Chem., 25, 583 (2013); doi:10.14233/ajchem.2013.13199B; B.K. Rai, S.N. Vidhyarthi, P. Kumar, S. Kumari, K. Lakshmi and R. Singh, Asian J. Chem., 25, 941 (2013); doi:10.14233/ajchem.2013.13199.
- B.K. Rai, J. Indian Chem. Soc., 90, 941 (2013).
- (a) H.P. Choudhry, S.P. Sharma, C.L. Rai and B.K. Rai, Oriental J. Chem., 29, 963 (2013); doi:10.13005/ojc/290315. ; (b) B.K. Rai and R. Kumari, Orient J. Chem., 29, 1163 (2013); doi:10.13005/ojc/290345.; (c) A. Kumar, U.S. Yadav and B.K. Rai, Oriental J. Chem., 29, 1203 (2013); doi:10.13005/ojc/290353.
- A.I. Vogel, Revised by J. Bessett, R.C. Denny, J.H. Jeffery and J. Mendham, A Textbook of Quantitative Chemical Analysis, London, edn 5 (1996).
- B.A. Gingras, R.L. Somorjai and C.H. Bayley, Can. J. Chem., 39, 974 (1961); doi:10.1139/v61-122.
- R.K. Agarwal, H. Agarwal and I. Chakraborti, Synth. React. Inorg. Met. Org. Chem., 25, 679 (1995); doi:10.1080/15533179508218256.
- N.K. Singh, A.K. Shrivastava and R.C. Agarwal, Indian J. Chem., 22A, 704 (1984).
- W. Kemp, Organic Spectroscopy, Palgrove, New York, edn 3 (2008).
- R. Silverstein and X.W. Francis, Spectrometric Identification of Organic Compounds, John Wiley & Sons, edn 3 (2008).
- S.N. Chaubey, J.P. Shrivastava and L.K. Mishra, Inorg. Chim. Acta, 23, 1 (1977); doi:10.1016/S0020-1693(00)94732-7.
- M. Goldstein and D. Unsworth, Inorg. Chim. Acta, 4, 342 (1970); doi:10.1016/S0020-1693(00)93301-2.
- R.G. Gadag and M.R. Gajendragad, Indian J. Chem., 16A, 703 (1978).
- P.S. Mane, S.G. Shridhar, B.R. Arbad and T.K. Chondekar, Indian J. Chem., 40A, 648 (2000).
- A.B.P. Lever, Inorganic Electronic Spectroscopy Elsevier, Amsterdam; p. 395 (1968).
- B.N. Friggis, Introduction to Ligand Field Wiley Eastern Ltd., New Delhi, p. 279 (1976).
- R.L. Carlin and A.J. Van Dryneveledt, Magnetic Properties of Transition Metal Compounds, Springer, Verlag, New York (1997).
- A.P. Mishra, M. Khare and S.K. Gautam, Synth. React. Inorg. Metal-Org. Chem, 32, 1485 (2002); doi:10.1081/SIM-120014864.
- L. Sacconi, Transition Met. Chem., 4, 212 (1968).
- C. Singh, H.K. Parwana, G. Singh and R.S. Jolly, Asian J. Chem., 12, 1 (2000).
- P.K. Mukhurjee, K. Saha, S.N. Giri, M. Pal and B.P. Saha, Indian J. Microbiol., 35, 320 (1995).
- P.S. Mehta, D.M. Purohit and V.H. Shah, Indian J. Heterocycl. Chem., 6, 271 (1997).
- A. Chaudhary, R. Swaroop and R. Singh, Bol. Soc. Chil. Quim., 47, 203 (2002); doi:10.4067/S0366-16442002000300002.
- A. Chaudhary, S. Dave, R.K. Saini, R.V. Singh, Main Group Met. Chem., 24, 217 (2001); doi:10.1515/MGMC.2001.24.4.217.
References
A. Albert and G.B. Barlin, J. Chem. Soc., 3129 (1962); doi:10.1039/JR9620003129.
M.M. Ghorab, S. El-Sayed Barakat, H.M. Saker and M.M. Abd Rabo, Arzneimitterlforschung, 56, 665 (2006); doi:10.1055/s-0031-1296769.
E.M. Jessy and D. Vachala, Pharmacologyonline, 2, 618 (2008).
V. Gupta, S.K. Kashaw, V. Jatav and P. Mishra, Med. Chem. Res., 17, 205 (2008); doi:10.1007/s00044-007-9054-3.
M.S. Hamed, M.M. Kamel, M.M. Kassem, M.S. Nofal and F.M. Ahmed, Acta Poloniae Pharm.-Drug Res., 67, 159 (2010).
A.M. Al-Obaid, S.G. Abdel-Hamide, H.A. El-Kashef, A.A.-M. Abdel-Aziz, A.S. El-Azab, H.A. Al-Khamees and H.I. El-Subbagh, Eur. J. Med. Chem., 44, 2379 (2009); doi:10.1016/j.ejmech.2008.09.015.
M.A. Al-Omar, A.S. El-Azb, H.A. El-Obeid and S.G. Abdel Hamcide, J. Saudi Chem. Soc., 10, 113 (2006).
A. Kumar, S. Sharma, K. Archana, K. Bajaj, S. Sharma, H. Panwar, T. Singh and V.K. Srivastava, Bioorg. Med. Chem., 11, 5293 (2003); doi:10.1016/S0968-0896(03)00501-7.
C. Lu, J. Yang, J. Chinag, M. Hour, K. Lin, J. Lin, W. Huang, M. Tsuzuki, T. Leel and J. Chung, PlosOne, 7, 1 (2012).
B.K. Rai, S.N. Vidyarthi, O.M. Prakash and A. Baluni, Orient J. Chem., 29, 801 (2013); doi:10.13005/ojc/290264.
B.K. Rai, R. Singh, P. Anand, S.K. Singh and A. Amit, Orient J. Chem., 29, 753 (2013); doi:10.13005/ojc/290254; (b) B.K. Rai, R. Anand, Asian J. Chem., 25, 480 (2013); doi:10.14233/ajchem.2013.13199C.
B.K. Rai, A. Thakur and Divya Asian J. Chem., 25, 583 (2013); doi:10.14233/ajchem.2013.13199B; B.K. Rai, S.N. Vidhyarthi, P. Kumar, S. Kumari, K. Lakshmi and R. Singh, Asian J. Chem., 25, 941 (2013); doi:10.14233/ajchem.2013.13199.
B.K. Rai, J. Indian Chem. Soc., 90, 941 (2013).
(a) H.P. Choudhry, S.P. Sharma, C.L. Rai and B.K. Rai, Oriental J. Chem., 29, 963 (2013); doi:10.13005/ojc/290315. ; (b) B.K. Rai and R. Kumari, Orient J. Chem., 29, 1163 (2013); doi:10.13005/ojc/290345.; (c) A. Kumar, U.S. Yadav and B.K. Rai, Oriental J. Chem., 29, 1203 (2013); doi:10.13005/ojc/290353.
A.I. Vogel, Revised by J. Bessett, R.C. Denny, J.H. Jeffery and J. Mendham, A Textbook of Quantitative Chemical Analysis, London, edn 5 (1996).
B.A. Gingras, R.L. Somorjai and C.H. Bayley, Can. J. Chem., 39, 974 (1961); doi:10.1139/v61-122.
R.K. Agarwal, H. Agarwal and I. Chakraborti, Synth. React. Inorg. Met. Org. Chem., 25, 679 (1995); doi:10.1080/15533179508218256.
N.K. Singh, A.K. Shrivastava and R.C. Agarwal, Indian J. Chem., 22A, 704 (1984).
W. Kemp, Organic Spectroscopy, Palgrove, New York, edn 3 (2008).
R. Silverstein and X.W. Francis, Spectrometric Identification of Organic Compounds, John Wiley & Sons, edn 3 (2008).
S.N. Chaubey, J.P. Shrivastava and L.K. Mishra, Inorg. Chim. Acta, 23, 1 (1977); doi:10.1016/S0020-1693(00)94732-7.
M. Goldstein and D. Unsworth, Inorg. Chim. Acta, 4, 342 (1970); doi:10.1016/S0020-1693(00)93301-2.
R.G. Gadag and M.R. Gajendragad, Indian J. Chem., 16A, 703 (1978).
P.S. Mane, S.G. Shridhar, B.R. Arbad and T.K. Chondekar, Indian J. Chem., 40A, 648 (2000).
A.B.P. Lever, Inorganic Electronic Spectroscopy Elsevier, Amsterdam; p. 395 (1968).
B.N. Friggis, Introduction to Ligand Field Wiley Eastern Ltd., New Delhi, p. 279 (1976).
R.L. Carlin and A.J. Van Dryneveledt, Magnetic Properties of Transition Metal Compounds, Springer, Verlag, New York (1997).
A.P. Mishra, M. Khare and S.K. Gautam, Synth. React. Inorg. Metal-Org. Chem, 32, 1485 (2002); doi:10.1081/SIM-120014864.
L. Sacconi, Transition Met. Chem., 4, 212 (1968).
C. Singh, H.K. Parwana, G. Singh and R.S. Jolly, Asian J. Chem., 12, 1 (2000).
P.K. Mukhurjee, K. Saha, S.N. Giri, M. Pal and B.P. Saha, Indian J. Microbiol., 35, 320 (1995).
P.S. Mehta, D.M. Purohit and V.H. Shah, Indian J. Heterocycl. Chem., 6, 271 (1997).
A. Chaudhary, R. Swaroop and R. Singh, Bol. Soc. Chil. Quim., 47, 203 (2002); doi:10.4067/S0366-16442002000300002.
A. Chaudhary, S. Dave, R.K. Saini, R.V. Singh, Main Group Met. Chem., 24, 217 (2001); doi:10.1515/MGMC.2001.24.4.217.