Structural Elucidation and Antibacterial Studies on Half-Sandwich Ruthenium(II) Complexes Incorporating Arene, Phosphine, Arsine and Thioamide Ligands

Abstract

The half-sandwich arene complexes of ruthenium(II) incorporating arsine, phosphine and thioamide ligands with formula [Ru(h⁶-arene)(ER₃)(AEtT)]⁺BPh₄^– h⁶-arene = C₆H₆ or p-cymene; E = P/As; R = C₆H₅/C₆H₅CH₂; AEtT = 4-amino-3-ethyl-5-mercapto-1,2,4-triazole bidentate mononegative anion) are prepared and investigated. The reaction products have been characterized by elemental analyses, conductometric, magnetic, IR, UV-visible and ¹H NMR spectra. Antibacterial activities of ligand and complexes are tested against E. coli, B. subtilus and S. aureus. The data revealed that all the complexes are more active than free thioamide ligand.