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Microwave Solid Phase Synthesis, Characterization and Antimicrobial Activities of Bis(5-chloro-2-hydroxybenzaldehyde)ethane-1,2-diamine-Zinc(II)
Corresponding Author(s) : Suo-Ping Xu
Asian Journal of Chemistry,
Vol. 28 No. 1 (2016): Vol 28 Issue 1
Abstract
One mononuclear complex (1) has been designed and synthesized by bis(5-chloro-2-hydroxybenzaldehyde)ethane-1,2-diamine (L) with Zn(CH3COO)2·2H2O in microwave radiation assistance. The complex was characterized by X-ray crystallography, confirming that the central zinc(II) was coordinated by two oxygen atoms, two nitrogen atoms from L. The complex was assayed for in vitro antibacterial (B. subtilis, S. aureus, S. faecalis, P. aeruginosa, E. coli and E. cloacae) activities and showed better antimicrobial activity against Gram-positive strains than Gram-negative strains.
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- S.-P. Xu, L. Shi, P.-C. Lv, R.-Q. Fang and H.-L. Zhu, J. Coord. Chem., 62, 2048 (2009); doi:10.1080/00958970902741251.
- L. Shi, H.-M. Ge, S.-H. Tan, H.-Q. Li, Y.-C. Song, H.-L. Zhu and R.-X. Tan, Eur. J. Med. Chem., 42, 558 (2007); doi:10.1016/j.ejmech.2006.11.010.
- A. Roth, E.T. Spielberg and W. Plass, Inorg. Chem., 46, 4362 (2007); doi:10.1021/ic070088i.
- J.D. Ranford, J.J. Vittal and Y.M. Wang, Inorg. Chem., 37, 1226 (1998); doi:10.1021/ic970805g.
- S.-P. Xu, Y. Pei, G. Xu, W.-X. Su and J.-X. Shu, J. Xuzhou Norm. Univ. Nat. Sci. Ed., 28, 57 (2010).
- L.-M. Wu, H.-B. Teng, X.-C. Feng, X.-B. Ke, Q.-F. Zhu, J.-T. Su, W.-J. Xu and X.-M. Hu, Cryst. Growth Des., 7, 1337 (2007); doi:10.1021/cg070196f.
- S.-P. Xu, P.-C. Lv, L. Shi and H.-L. Zhu, Arch. Pharm. Chem. Life Sci., 343, 282 (2010).
- P. Prusis, M. Dambrova, V. Andrianov, E. Rozhkov, V. Semenikhina, I. Piskunova, E. Ongwae, T. Lundstedt, I. Kalvinsh and J.E.S. Wikberg, J. Med. Chem., 47, 3105 (2004); doi:10.1021/jm031127c.
- S. Ren, R. Wang, K. Komatsu, P. Bonaz-Krause, Y. Zyrianov, C.E. McKenna, C. Csipke, Z.A. Tokes and E.J. Lien, J. Med. Chem., 45, 410 (2002); doi:10.1021/jm010252q.
- P.H. Wang, J.G. Keck, E.J. Lien and M.M.C. Lai, J. Med. Chem., 33, 608 (1990); doi:10.1021/jm00164a023.
- S.-P. Xu, B.-F. Ruan, Q.-Y. Pan and R.-T. Hu, J. Coord. Chem., 64, 2489 (2011); doi:10.1080/00958972.2011.601459.
- G.M. Sheldrick, SHELXL V5.1 Software Reference Manual, Bruker AXS, Inc., Madison, WI, USA (1997).
- J. Meletiadis, J.F. Meis, J.W. Mouton, J.P. Donnelly and P.E. Verweij, J. Clin. Microbiol., 38, 2949 (2000).
- K. Nakamato, Infrared Spectra of Inorganic and Coordination Compounds, Wiley, New York (1994).
- J.-M. Li, J.-Z. Li, H.-Q. Zhang and L.-Y. Xu, Inorg. Chem. Commun., 13, 573 (2010); doi:10.1016/j.inoche.2010.01.023.
- M. Nath, S. Pokharia, X. Song, G. Eng, M. Gielen, M. Kemmer, M. Biesemans, R. Willem and D. De Vos, Appl. Organomet. Chem., 17, 305 (2003); doi:10.1002/aoc.451.
References
S.-P. Xu, L. Shi, P.-C. Lv, R.-Q. Fang and H.-L. Zhu, J. Coord. Chem., 62, 2048 (2009); doi:10.1080/00958970902741251.
L. Shi, H.-M. Ge, S.-H. Tan, H.-Q. Li, Y.-C. Song, H.-L. Zhu and R.-X. Tan, Eur. J. Med. Chem., 42, 558 (2007); doi:10.1016/j.ejmech.2006.11.010.
A. Roth, E.T. Spielberg and W. Plass, Inorg. Chem., 46, 4362 (2007); doi:10.1021/ic070088i.
J.D. Ranford, J.J. Vittal and Y.M. Wang, Inorg. Chem., 37, 1226 (1998); doi:10.1021/ic970805g.
S.-P. Xu, Y. Pei, G. Xu, W.-X. Su and J.-X. Shu, J. Xuzhou Norm. Univ. Nat. Sci. Ed., 28, 57 (2010).
L.-M. Wu, H.-B. Teng, X.-C. Feng, X.-B. Ke, Q.-F. Zhu, J.-T. Su, W.-J. Xu and X.-M. Hu, Cryst. Growth Des., 7, 1337 (2007); doi:10.1021/cg070196f.
S.-P. Xu, P.-C. Lv, L. Shi and H.-L. Zhu, Arch. Pharm. Chem. Life Sci., 343, 282 (2010).
P. Prusis, M. Dambrova, V. Andrianov, E. Rozhkov, V. Semenikhina, I. Piskunova, E. Ongwae, T. Lundstedt, I. Kalvinsh and J.E.S. Wikberg, J. Med. Chem., 47, 3105 (2004); doi:10.1021/jm031127c.
S. Ren, R. Wang, K. Komatsu, P. Bonaz-Krause, Y. Zyrianov, C.E. McKenna, C. Csipke, Z.A. Tokes and E.J. Lien, J. Med. Chem., 45, 410 (2002); doi:10.1021/jm010252q.
P.H. Wang, J.G. Keck, E.J. Lien and M.M.C. Lai, J. Med. Chem., 33, 608 (1990); doi:10.1021/jm00164a023.
S.-P. Xu, B.-F. Ruan, Q.-Y. Pan and R.-T. Hu, J. Coord. Chem., 64, 2489 (2011); doi:10.1080/00958972.2011.601459.
G.M. Sheldrick, SHELXL V5.1 Software Reference Manual, Bruker AXS, Inc., Madison, WI, USA (1997).
J. Meletiadis, J.F. Meis, J.W. Mouton, J.P. Donnelly and P.E. Verweij, J. Clin. Microbiol., 38, 2949 (2000).
K. Nakamato, Infrared Spectra of Inorganic and Coordination Compounds, Wiley, New York (1994).
J.-M. Li, J.-Z. Li, H.-Q. Zhang and L.-Y. Xu, Inorg. Chem. Commun., 13, 573 (2010); doi:10.1016/j.inoche.2010.01.023.
M. Nath, S. Pokharia, X. Song, G. Eng, M. Gielen, M. Kemmer, M. Biesemans, R. Willem and D. De Vos, Appl. Organomet. Chem., 17, 305 (2003); doi:10.1002/aoc.451.