A New Eremophilane-Type Sesquiterpene from Flue-Cured Tobacco and Its Anti-tobacco Mosaic Virus Activity

Rong Hu; Shan-Zhai Shang; Wei Zhao; Yong-Kuan Chen; Guang-Yu Yang; Zhi-Hua Liu

doi:10.14233/ajchem.2015.17381

Issue

Vol. 27 No. 5 (2015): Vol 27 Issue 5

Issue Published : February 20, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

A New Eremophilane-Type Sesquiterpene from Flue-Cured Tobacco and Its Anti-tobacco Mosaic Virus Activity

https://doi.org/10.14233/ajchem.2015.17381

Rong Hu

Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Shan-Zhai Shang

Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Wei Zhao

Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Yong-Kuan Chen

Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Guang-Yu Yang

Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Zhi-Hua Liu

Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Corresponding Author(s) : Zhi-Hua Liu

zhihualiu@163.com, ygy1110@163.com

Asian Journal of Chemistry, Vol. 27 No. 5 (2015): Vol 27 Issue 5
Article Published : February 20, 2015

Abstract

A new eremophilane-type sesquiterpene, tobterpene B (1), was isolated from the stems of flue-cured tobacco (a variety of Nicotiana tabacum L). Its structure was elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compound 1 was tested for its anti-tobacco mosaic virus (anti-TMV) activity and it shows potential anti-tobacco mosaic virus activity with inhibition rates of 15.2 %.

Keywords

Sesquiterpene Flue-cured tobacco Anti-tobacco mosaic virus activity

Hu, R., Shang, S.-Z., Zhao, W., Chen, Y.-K., Yang, G.-Y., & Liu, Z.-H. (2015). A New Eremophilane-Type Sesquiterpene from Flue-Cured Tobacco and Its Anti-tobacco Mosaic Virus Activity. Asian Journal of Chemistry, 27(5), 1947–1948. https://doi.org/10.14233/ajchem.2015.17381

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References

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References

The Editorial Committee of the Administration Bureau of Flora of China, Flora of China, 67 vols. (Beijing Science and Technology Press, Beijing, China (2005).

T.W. Hu and Z. Mao, Tob. Control, 15(suppl. 1), i37 (2006); doi:10.1136/tc.2005.014621.

A. Rodgman and T.A. Perfetti, The Chemical Components of Tobacco and Tobacco Smoke, CRC Press, Taylor and Francis Group, Boca Raton, Florida (2008).

A.P. Cavender and M. Alban, J. Ethnobiol. Ethnomed., 5, 3 (2009); doi:10.1186/1746-4269-5-3.

A. Inta, P. Shengji, H. Balslev, P. Wangpakapattanawong and C. Trisonthi, J. Ethnopharmacol., 116, 134 (2008); doi:10.1016/j.jep.2007.12.015.

X. Feng, J.-S. Wang, J. Luo and L.-Y. Kong, J. Asian Nat. Prod. Res., 12, 252 (2010); doi:10.1080/10286020903550947.

Y. Shinozaki, T. Tobita, M. Mizutani and T. Matsuzaki, Biosci. Biotechnol. Biochem., 60, 903 (1996); doi:10.1271/bbb.60.903.

T. Pettersson, A.M. Eklund and I. Wahlberg, J. Agric. Food Chem., 41, 2097 (1993); doi:10.1021/jf00035a052.

X.C. Wei, S.C. Sumithran, A.G. Deaciuc, H.R. Burton, L.P. Bush, L.P. Dwoskin and P.A. Crooks, Life Sci., 78, 495 (2005); doi:10.1016/j.lfs.2005.09.009.

T. Braumann, G. Nicolaus, W. Hahn and H. Elmenhorst, Phytochemistry, 29, 3693 (1990); doi:10.1016/0031-9422(90)85311-3.

Y.K. Chen, X.S. Li, G.Y. Yang, Z.Y. Chen, Q.F. Hu and M.M. Miao, J. Asian Nat. Prod. Res., 14, 450 (2012); doi:10.1080/10286020.2012.669578.

Q.-F. Hu, G. Yang, X. Li, X. Yang, H. Mu, Y. Chen and X.-M. Gao, Heterocycles, 85, 147 (2012); doi:10.3987/COM-11-12349.

Z.Y. Chen, J.L. Tan, G.Y. Yang, M.M. Miao, Z.Y. Chen and T.F. Li, Phytochem. Lett., 5, 233 (2012); doi:10.1016/j.phytol.2012.01.001.

Y. Chen, T. Li, Z.-Y. Chen, G. Yang, M. Miao and J. Tan, Heterocycles, 83, 2381 (2011); doi:10.3987/COM-11-12317.

G.D. Huang, Y.J. Yang, W.S. Wu and Y. Zhu, J. Nat. Prod., 73, 1954 (2010); doi:10.1021/np1004505.

Q.F. Hu, B. Zhou, X.M. Gao, L.Y. Yang, L.D. Shu, Y.Q. Shen, G.P. Li, C.T. Che and G.Y. Yang, J. Nat. Prod., 75, 1909 (2012); doi:10.1021/np300395m.

Issue

Vol. 27 No. 5 (2015): Vol 27 Issue 5

A New Eremophilane-Type Sesquiterpene from Flue-Cured Tobacco and Its Anti-tobacco Mosaic Virus Activity

Corresponding Author(s) : Zhi-Hua Liu

Abstract

Keywords

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