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One Pot Synthesis and Characterization of Some Novel Schiff Bases with 1,3,4-Thiadiazole Unit
Corresponding Author(s) : Jian Zhang
Asian Journal of Chemistry,
Vol. 27 No. 4 (2015): Vol 27 Issue 4
Abstract
A series of novel benzimidazole substituted Schiff bases were synthesized by the reaction of aromatic aldehydes with the corresponding ethyl acetoacetate or methyl acetoacetate and 1,3,4-thiadiazole. These compounds have been characterized by 1H NMR, IR and mass spectra.
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References
P.A. Vigato and S. Tamburini, Coord. Chem. Rev., 248, 1717 (2004); doi:10.1016/j.cct.2003.09.003.
P. Vicini, A. Geronikaki, M. Incerti, B. Busonera, G. Poni, C.A. Cabras and P. La Colla, Bioorg. Med. Chem., 11, 4785 (2003); doi:10.1016/S0968-0896(03)00493-0.
S.M. Sondhi, N. Singh, A. Kumar, O. Lozach and L. Meijer, Bioorg. Med. Chem., 14, 3758 (2006); doi:10.1016/j.bmc.2006.01.054.
M.T.H. Tarafder, A. Kasbollah, N. Saravanan, K.A. Crouse, A.M. Ali and K. Tin Oo, Biochem. Mol. Biol. Biophys., 6, 85 (2002); doi:10.1080/10258140290027207.
L. Shi, H.-M. Ge, S.-H. Tan, H.-Q. Li, Y.-C. Song, H.-L. Zhu and R.-X. Tan, Eur. J. Med. Chem., 42, 558 (2007); doi:10.1016/j.ejmech.2006.11.010.
K. Cheng, Q.Z. Zheng, Y. Qian, L. Shi, J. Zhao and H.L. Zhu, Bioorg. Med. Chem., 17, 7861 (2009); doi:10.1016/j.bmc.2009.10.037.
İ. Kücükgüzel, Ş. Güniz Kücükgüzel, S. Rollas, G. Ötük-Saniş, O. Özdemir, İ. Bayrak, T. Altuğ and J.P. Stables, IL Farmaco, 59, 893 (2004); doi:10.1016/j.farmac.2004.07.005.
K.P. Bryliakov and E.P. Talsi, J. Mol. Catal. Chem., 264, 280 (2007); doi:10.1016/j.molcata.2006.09.038.
M.Y. Khuhawar, M.A. Mughal and A.H. Channar, Eur. Polym. J., 40, 805 (2004); doi:10.1016/j.eurpolymj.2003.11.020.
Z. Ates-Alagöz, M. Alp, C. Kus, S. Yildiz, E. Buyukbingöl and H. Göker, Arch. Pharm. Chem. Life Sci., 339, 74 (2006); doi:10.1002/ardp.200500168.
Z. Ates-Alagoz, S. Yildiz and E. Buyukbingol, Chemotherapy, 53, 110 (2007); doi:10.1159/000100011.
M. Hranjec, M. Kralj, I. Piantanida, M. Sedic, L. Suman, K. Pavelic and G. Karminski-Zamola, J. Med. Chem., 50, 5696 (2007); doi:10.1021/jm070876h.
M. Hranjec, I. Piantanida, M. Kralj, L. Suman, K. Pavelić and G. Karminski-Zamola, J. Med. Chem., 51, 4899 (2008); doi:10.1021/jm8000423.
M. Hranjec, G. Pavlović, M. Marjanović, M. Kralj and G. Karminski-Zamola, Eur. J. Med. Chem., 45, 2405 (2010); doi:10.1016/j.ejmech.2010.02.022.
K. Starcević, M. Kralj, K. Ester, I. Sabol, M. Grce, K. Pavelić and G. Karminski-Zamola, Bioorg. Med. Chem., 15, 4419 (2007); doi:10.1016/j.bmc.2007.04.032.
S.M. Rida, S.A.M. El-Hawash, H.T. Fahmy, A.A. Hazzaa and M.M. El-Meligy, Arch. Pharm. Res., 29, 826 (2006); doi:10.1007/BF02973901.
J. Velík, V. Baliharová, J. Fink-Gremmels, S. Bull, J. Lamka and L. Skálová, Res. Vet., 76, 95 (2004); doi:10.1016/j.rvsc.2003.08.005.
K. Cheng, Q.Z. Zheng, J. Hou, Y. Zhou, C.-H. Liu, J. Zhao and H.-L. Zhu, Bioorg. Med. Chem., 18, 2447 (2010); doi:10.1016/j.bmc.2010.02.052.
G.G. Tu, S.H. Li, H.M. Huang, G. Li, F. Xiong, X. Mai, H.W. Zhu, B.H. Kuang and W.F. Xu, Bioorg. Med. Chem., 16, 6663 (2008); doi:10.1016/j.bmc.2008.05.081.