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Vol. 27 No. 3 (2015): Vol 27 Issue 3

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Synthesis, Characterization and Antimicrobial Properties of Some Transition Metal Complexes with NS-Chelating Schiff Base Ligand Incorporating Thiophene and Sulfonamide Moieties

https://doi.org/10.14233/ajchem.2015.17627
Yiheyis Bogale Zemede
Department of Chemistry, Faculty of Science and Humanity, Anna University Chennai-600 025, India
D. Nithyakalyani
Centre for Biotechnology, Alagappa College of Technology, Anna University, Chennai-600 025, India
S. Ananda Kumar
Department of Chemistry, Faculty of Science and Humanity, Anna University Chennai-600 025, India

Corresponding Author(s) : S. Ananda Kumar

sri_anand_72@yahoo.com

Asian Journal of Chemistry, Vol. 27 No. 3 (2015): Vol 27 Issue 3

Abstract

Schiff base namely 4-[(thiophene-2-yl)methyleneamino]phenyl sulfonamide (L) and its Co(II), Ni(II), Cu(II) and Zn(II) complexes were synthesized and characterized by UV-visible, IR, 1H NMR, MS-EI, elemental analysis and TGA. Molar conductance and magnetic susceptibility of the complexes were also analyzed. Elemental analyses confirmed a 2:1 molar ratio of ligand to metal ion of the complexes. IR spectra revealed that the ligand is coordinated to the metal ions through azomethine-N and thiophene-S. On the basis of experimental data octahedral geometry was proposed for all complexes. Thermal studies together with IR showed the presence of lattice and coordinated water molecules in all complexes. The in vitro antimicrobial activities of the compounds were tested against S. aureus, K. pneumoniae, C. albicans and C. krusei by the agar well diffusion assay. The result indicated that the ligand become antimicrobially active on chelation with metal ions. It was found that Cu(II) complex showed the highest antibacterial activity among all complexes.

Keywords

Transition metal(II) complexes 4-[(Thiophene-2-yl)methyleneamino]phenyl sulphonamide Octahedral geometry
Bogale Zemede, Y., Nithyakalyani, D., & Ananda Kumar, S. (2015). Synthesis, Characterization and Antimicrobial Properties of Some Transition Metal Complexes with NS-Chelating Schiff Base Ligand Incorporating Thiophene and Sulfonamide Moieties. Asian Journal of Chemistry, 27(3), 941–948. https://doi.org/10.14233/ajchem.2015.17627
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