Copyright (c) 2015 AJC
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Chemical Composition, Antioxidant and Antimicrobial Activity of the Essential Oil of Phellodendron amurense (Rupr.) from China
Corresponding Author(s) : L. Xu
Asian Journal of Chemistry,
Vol. 27 No. 3 (2015): Vol 27 Issue 3
Abstract
The essential oil of Phellodendron amurense has been isolated from fruits collected in their native habitat China. Hydrodistillation of P. amurense afforded a pale yellow oil in 1.4 % (w/w) yield. The chemical composition of this essential oil was analyzed by GC-MS. Twenty-one compounds were identified, accounting for 97 % of the total oil. There were five most abundant constituents (greater than 5 %) were myrcene (51.7 %), 2-methyl-6-methyleneocta-3,7-dien-2-ol (7.4 %), 1,2-benzenedicarboxylic acid-bis(2-methylpropyl)-ester (7.2 %), 2-methyl-6-methyleneocta-1,7-dien-3-ol (7.1 %) and a-phellandrene (5.2 %).The essential oil of P. amurense showed antioxidant activity (IC50, 2.32 μg/mL) and broad spectrum fumigant and contact antimicrobial activity against all microbial strains tested (MIC or IC50, 0.12-1.36 μg/mL). These findings suggest that the essential oil may be used as an antioxidant or antimicrobial agent.
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References
K. Kishi, K. Yoshikawa and S. Arihara, Phytochemistry, 31, 1335 (1992); doi:10.1016/0031-9422(92)80285-M.
Y. Ida, Y. Satoh, M. Ohtsuka, M. Nagasao and J. Shoji, Phytochemistry, 35, 209 (1993); doi:10.1016/S0031-9422(00)90536-3.
D.R.L. Caccioni, M. Guizzardi, D.M. Biondi, A. Renda and G. Ruberto, Int. J. Food Microbiol., 43, 73 (1998); doi:10.1016/S0168-1605(98)00099-3.
N. Sharma and A. Tripathi, Microbiol. Res., 163, 337 (2008); doi:10.1016/j.micres.2006.06.009.
S. Droby, A. Eick, D. Macarisin, L. Cohen, G. Rafael, R. Stange, G. McColum, N. Dudai, A. Nasser, M. Wisniewski and R. Shapira, Postharvest Biol. Technol., 49, 386 (2008); doi:10.1016/j.postharvbio.2008.01.016.
Y. Gong, Y. Huang, L. Zhou, X. Shi, Z. Guo, M. Wang and W. Jiang, J. Essent. Oil Res., 21, 174 (2009); doi:10.1080/10412905.2009.9700141.
Y. Gong, L. Zhou, X. Shi, Z. Ma, Z. Guo, M. Wang, J. Wang and X. Li, J. Essent. Oil Res, 23, 108 (2011); doi:10.1080/10412905.2011.9700436.
K.A. Hammer, C.F. Carson and T.V. Riley, J. Appl. Microbiol., 86, 985 (1999); doi:10.1046/j.1365-2672.1999.00780.x.
M.B. Isman, Crop Prot., 19, 603 (2000); doi:10.1016/S0261-2194(00)00079-X.
S. Burt, Int. J. Food Microbiol., 94, 223 (2004); doi:10.1016/j.ijfoodmicro.2004.03.022.
A. Lis, E. Boczek and J. Gora, Flavour Fragrance J., 19, 549 (2004); doi:10.1002/ffj.1349.
W. Wang, Y.G. Zu, Y.J. Fu, J. Reichling, U. Suschke, S. Nokemper and Y. Zhang, Am. J. Chin. Med., 37, 195 (2009); doi:10.1142/S0192415X09006655.
H. Yu, K. Kim, J. Cha, H. Kim, Y. Lee, N.-Y. Choi and Y.-O. You, J. Med. Food, 8, 454 (2005); doi:10.1089/jmf.2005.8.454.
M. Tan, L. Zhou, M. Qin, D. Li, W. Jiang, Y. Wang and X. Hao, J. Essent. Oil Res., 19, 197 (2007); doi:10.1080/10412905.2007.9699258.
H. Van den Dool and P.D. Kratz, J. Chromatogr. A, 11, 463 (1963); doi:10.1016/S0021-9673(01)80947-X.
N. Mimica-Dukic, B. Bozin, M. Sokovic and N. Simin, J. Agric. Food Chem., 52, 2485 (2004); doi:10.1021/jf030698a.
NCCLS, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Approved Standard, Wayne, USA, edn 5 (2001).
L. Xu, L. Zhou, J. Zhao, J. Li, X. Li and J. Wang, J. Appl. Microbiol., 46, 68 (2008); doi:10.1111/j.1472-765X.2007.02264.x.
J. Wang, H. Liu, J. Zhao, H. Gao, L. Zhou, Z. Liu, Y. Chen and P. Sui, Molecules, 15, 5807 (2010); doi:10.3390/molecules15085807.
C.L. Wilson, J.M. Solar, A. El Ghaouth and M.E. Wisniewski, Plant Dis., 81, 204 (1997); doi:10.1094/PDIS.1997.81.2.204.
P. Sandra and C. Bicchi, Capillary Gas Chromatography in Essential Oil Analysis, Alfred Huethig Verlag, Heidelberg, p. 3 (1987).
K.H.C. Baser and G. Buchbauer, Handbook of Essential Oils: Science, Technology and Applications, Taylor & Francis, Boca Raton, pp. 1-32 (2010).
Z.W.Y. Kang, Q. Ji and J.M. Wang, Chem. Nat. Comp., 45, 575 (2009); doi:10.1007/s10600-009-9371-5.
Q.Z. Faridah, A.H.A. Abdelmageed, A.N. Nor Hazirah and M. Yaacob, J. Med. Plants Res., 4, 2700 (2010).
Y. Inoue, A. Shiraishi, T. Hada, H. Hamashima and J. Shimada, FEMS Microbiol. Lett., 237, 325 (2004); doi:10.1111/j.1574-6968.2004.tb09714.x.
L. Jirovetz, S. Bail, G. Buchbauer, Z. Denkova, A. Slavchev, A. Stoyanova, E. Schmidt and M. Geissler, Sci. Pharm., 74, 189 (2006); doi:10.3797/scipharm.2006.74.189.
H.J.D. Dorman and S.G. Deans, J. Appl. Microbiol., 88, 308 (2000); doi:10.1046/j.1365-2672.2000.00969.x.