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Design and Synthesis of Novel Hapten and Antigen for Dichlorvos: A Famous Organophosphorus Pesticide
Corresponding Author(s) : Shuo Wang
Asian Journal of Chemistry,
Vol. 27 No. 3 (2015): Vol 27 Issue 3
Abstract
Dichlorvos, a famous organophosphorus pesticide, was widely used in agriculture to defend insects. It was difficult to obtain the antigen of dichlorvos because of its little molecular without active group. In this paper, a good strategy was carried out for designing hapten and complete antigens of dichlorvos. Hapten was synthesized facilely and simply in good yield. The novel antigen of dichlorvos was prepared successfully by active ester method.
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References
K.D. Racke, Rev. Environ. Contam. Toxicol., 131, 1 (1993).
A.K. Gupta, G.P. Verma and K.L. Jain, J. Environ. Biol., 29, 837 (2008).
Y. Liang, X.J. Liu, Y. Liu, X.Y. Yu and M.T. Fan, J. Anal. Chim. Acta, 615, 174 (2008); doi:10.1016/j.aca.2008.03.050.
B. Liu, Y. Ge, Y. Zhang, Y. Song, Y. Lv, X. Wang and S. Wang, Food Agric. Immunol., 23, 157 (2012); doi:10.1080/09540105.2011.608120.
Y.A. Cho, J.A. Seok, H.S. Lee, Y.J. Kim, Y.C. Park and Y.T. Lee, J. Chim. Acta, 522, 215 (2004); doi:10.1016/j.aca.2004.05.083.
Q. Zhang, L. Wang, K.C. Ahn, Q. Sun, B.S. Hu, J. Wang and F.Q. Liu, J. Anal. Chim. Acta, 596, 303 (2007); doi:10.1016/j.aca.2007.06.009.
L. Wang, Q. Zhang, D. Chen, Y. Liu, C. Li, B. Hu, D. Du and F. Liu, Anal. Lett., 44, 1591 (2011); doi:10.1080/00032719.2010.520391.
J.J. Manclus, J. Primo and A. Montoya, J. Agric. Food Chem., 44, 4052 (1996); doi:10.1021/jf960144q.
A.Y. Kolosova, J.H. Park, S.A. Eremin, S.J. Kang and D.H. Chung, J. Agric. Food Chem., 51, 1107 (2003); doi:10.1021/jf025801v.
J.V. Mercader and A. Montoya, J. Agric. Food Chem., 47, 1276 (1999); doi:10.1021/jf9808675.
Q. Feng, Y. Xu, Y. Zhou, L. Lu, F. Chen and X. Wang, J. Mol. Struct., 977, 100 (2010); doi:10.1016/j.molstruc.2010.05.020.