Copyright (c) 2014 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Modification of Poly(lactic acid-co-glycolic acid) Film via Blending with Polyacrylonitrile
Corresponding Author(s) : Fa-Gang Wang
Asian Journal of Chemistry,
Vol. 26 No. 3 (2014): Vol 26 Issue 3
Abstract
A series of poly(lactic acid-co-glycolic acid) (PLGA)/polyacrylonitrile blend films with different polyacrylonitrile mole content were prepared by casting the polymer blend solution in dimethyl sulfoxide. Surface morphologies of the PLGA/PAN blend films were studied by scanning electron microscopy. Thermal, mechanical, and chemical properties of PLGA/PAN blend films were investigated by differential scanning calorimeter, tensile tests and surface contact angle tests. It was displayed that the introduction of polyacrylonitrile could greatly modify the properties of PLGA films.
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References
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T. Paragkumar N, D. Edith and J.-L. Six, Appl. Surf. Sci., 253, 2758 (2006); doi:10.1016/j.apsusc.2006.05.047.
J.H. Jeong, D.W. Lim, D.K. Han and T.G. Park, Colloids Surf. B, 18, 371 (2000); doi:10.1016/S0927-7765(99)00162-9.
S.C.J. Loo, C.P. Ooi and Y.C.F. Boey, Polym. Degrad. Stab., 83, 259 (2004); doi:10.1016/S0141-3910(03)00271-4.
F. Ganji and M.J. Abdekhodaie, Carbohydr. Polym., 80, 740 (2010); doi:10.1016/j.carbpol.2009.12.021.
M.L. Houchin, S.A. Neuenswander and E.M. Topp, J. Control. Rel., 117, 413 (2007); doi:10.1016/j.jconrel.2006.11.023.
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N.A. Peppas, Y. Huang, M. Torres-Lugo, J.H. Ward and J. Zhang, Ann. Rev. Biomed. Eng., 2, 9 (2000); doi:10.1146/annurev.bioeng.2.1.9.
R. Langer, Ann. Biomed. Eng., 23, 101 (1995); doi:10.1007/BF02368317.
L.G. Cima, J.P. Vacanti, C. Vacanti, D. Ingber, D. Mooney and R. Langer, J. Biomech. Eng., 113, 143 (1991); doi:10.1115/1.2891228.
R.A. Jain, Biomaterials, 21, 2475 (2000); doi:10.1016/S0142-9612(00)00115-0.
H. Murakami, M. Kobayashi, H. Takeuchi and Y. Kawashima, J. Control. Rel., 67, 29 (2000); doi:10.1016/S0168-3659(99)00288-6.
J.L. Cleland, O.L. Johnson, S. Putney and A.J.S. Jones, Adv. Drug Deliv. Rev., 28, 71 (1997); doi:10.1016/S0169-409X(97)00051-3.
B. Bittner, C. Witt, K. Mäder and T. Kissel, J. Control. Rel., 60, 297 (1999); doi:10.1016/S0168-3659(99)00085-1.
A.A. Ignatius and L.E. Claes, Biomaterials, 17, 831 (1996); doi:10.1016/0142-9612(96)81421-9.
S. Stolnik, S.E. Dunn, M.C. Garnett, M.C. Davies, A.G.A. Coombes, D.C. Taylor, M.P. Irving, S.C. Purkiss, T.F. Tadros, S.S. Davis and L. Illum, Pharm. Res., 11, 1800 (1994); doi:10.1023/A:1018931820564.
A. Gopferich, S.J. Peter, A. Lucke, L. Lu and A.G. Mikos, J. Biomed. Mater. Res., 46, 390 (1999); doi:10.1002/(SICI)1097-4636(19990905)46:3<390::AID-JBM12>3.0.CO;2-N.
J.M. Anderson and K.M. Miller, Biomaterials, 5, 5 (1984); doi:10.1016/0142-9612(84)90060-7.
D.L. Elbert and J.A. Hubbell, Chem. Biol., 5, 177 (1998); doi:10.1016/S1074-5521(98)90062-X.
L.S. Wan, Z.K. Xu, X.J. Huang, A.F. Che and Z.G. Wang, J. Membr. Sci., 277, 157 (2006); doi:10.1016/j.memsci.2005.10.037.
M. Ulbricht and G. Belfort, J. Membr. Sci., 111, 193 (1996); doi:10.1016/0376-7388(95)00207-3.
B. Jung, J. Membr. Sci., 229, 129 (2004); doi:10.1016/j.memsci.2003.10.020.
J. Frahn, G. Malsch, H. Matuschewski, U. Schedler and H.H. Schwarz, J. Membr. Sci., 234, 55 (2004); doi:10.1016/j.memsci.2003.12.017.
H.-G. Hicke, I. Lehmann, G. Malsch, M. Ulbricht and M. Becker, J. Membr. Sci., 198, 187 (2002); doi:10.1016/S0376-7388(01)00595-6.
L.Q. Bai, L.J. Zhu, S.J. Min, L. Liu, Y.R. Cai and J.M. Yao, Appl. Surf. Sci., 254, 2988 (2008); doi:10.1016/j.apsusc.2007.10.049.