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Vol. 26 No. 2 (2014): Vol 26 Issue 2

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Antimicrobial and Antioxidant Properties of Lamium galactophyllum Boiss & Reuter, L. macrodon Boiss & Huet and L. amplexicaule from Turkish Flora

https://doi.org/10.14233/ajchem.2014.15748
Nurcan Erbil1
1Healthcare Vocational School, Ardahan University, 75000 Ardahan, Turkey 2Department of Biology, Faculty of Arts and Science, Mus Alparslan University, 49000 Mus, Turkey 3Department of Biology, Faculty of Arts and Science, Kahramanmaras Sutcu Imam University, 46000 Kahramanmaras, Turkey *Corresponding author: Tel: +90 478 211 37 50; E-mail: nurcanerbil@ardahan.edu.tr
Yusuf Alan2
1Healthcare Vocational School, Ardahan University, 75000 Ardahan, Turkey 2Department of Biology, Faculty of Arts and Science, Mus Alparslan University, 49000 Mus, Turkey 3Department of Biology, Faculty of Arts and Science, Kahramanmaras Sutcu Imam University, 46000 Kahramanmaras, Turkey *Corresponding author: Tel: +90 478 211 37 50; E-mail: nurcanerbil@ardahan.edu.tr
Metin Digrak3
1Healthcare Vocational School, Ardahan University, 75000 Ardahan, Turkey 2Department of Biology, Faculty of Arts and Science, Mus Alparslan University, 49000 Mus, Turkey 3Department of Biology, Faculty of Arts and Science, Kahramanmaras Sutcu Imam University, 46000 Kahramanmaras, Turkey *Corresponding author: Tel: +90 478 211 37 50; E-mail: nurcanerbil@ardahan.edu.tr

Asian Journal of Chemistry, Vol. 26 No. 2 (2014): Vol 26 Issue 2

Abstract

Some Lamium species have been used in folk medicine worldwide in the treatment of several desorders. This work aimed to screen the possible antimicrobial and antioxidant properties as well as total phenolic, resveratrol and flavonoid contents of extracts of three different Lamium species. According to analysis results the highest total phenolic concent was determined at Lamium galactophyllum (112.87 mg GAE/g extre). Quercetin and katesin were the major flavonoid contents for Lamium galactophyllum (respectively 296.7 and 323.35 μg/mL), Lamium macrodon (respectively 445.75 and 338.6 μg/mL) and Lamium amplexicaule (respectively 101.6 and 330.9 μg/mL). ABTS free radical scavenginig activity of plant extracts was higher than DPPH free radical scavenginig activity, but all plant extracts had free radical scavenging activity against DPPH and ABTS. Lamium galactophllum and Lamium macrodon exhibited more effective antimicrobial activity than Lamium amplexicaule. These results suggested that Lamium species used in this work had antimicrobial and antioxidant properties.

Keywords

Lamium galactophyllum Lamium macrodon Lamium amplexicaule Resveratrol-flavonoid contents.
Erbil1, N., Alan2, Y., & Digrak3, M. (2014). Antimicrobial and Antioxidant Properties of Lamium galactophyllum Boiss & Reuter, L. macrodon Boiss & Huet and L. amplexicaule from Turkish Flora. Asian Journal of Chemistry, 26(2), 549–554. https://doi.org/10.14233/ajchem.2014.15748
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References
  1. T. Ersöz, D. Kaya, F.N. Yalçın, C. Kazaz, E. Palaska, C.H. Gotfredsen, S.R. Jensen and İ. Çalış, Turk. J. Chem., 31, 155 (2007).
  2. R.F. Weiss, Herbal Medicine, Beaconsfield, pp. 313-314 (1988)..
  3. N.G. Bisset, Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on A Scientific Basis, Scientific Publishers, Stuttgart, pp. 288-291 (1994).
  4. B. Havsteen, Biochem. Pharmacol., 32, 1141 (1983); doi:10.1016/0006-2952(83)90262-9.
  5. E.J. Middleton and K. Chithan, in ed.: J.B. Harborne, The Impact of Plant Flavonoids on Mammalian Biology: Implications for Immunity, Inflammation and Cancer. In: The Flavonoids: Advances in Research Since 1986, Chapman & Hall, London, pp. 619-652 (1993).
  6. J.M. Grange and R.W. Davey, J. R. Soc. Med., 83, 159 (1990).
  7. J.B. Harborne and H. Baxter, Handbook of Natural Flavonoids, John Wiley & Sons, New York (1999).
  8. C.A. Rice-Evans, N.J. Miller and G. Paganga, Free Radic. Biol. Med., 20, 933 (1996); doi:10.1016/0891-5849(95)02227-9.
  9. S.E. Pollard, G.G. Kuhnle, D. Vauzour, K. Vafeiadou, X. Tzounis, M. Whiteman, C. Rice-Evans and J.P.E. Spencer, Biochem. Biophys. Res. Commun., 350, 960 (2006); doi:10.1016/j.bbrc.2006.09.131.
  10. P.H. Davis, Flora of Turkey and East Aegean Islands, 1965-1984, Vol. 1-10, Edinburgh University Press, Edinburgh.
  11. V.L. Singleton, R. Orthofer and R.M. Lamuela-Raventos, Oxidants and Antioxidants, 299, 152 (1999).
  12. M.S. Blois, Nature, 181, 1199 (1958); doi:10.1038/1811199a0.
  13. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C.A. Rice-Evans, Free Radic. Biol. Med., 26, 1231 (1999); doi:10.1016/S0891-5849(98)00315-3.
  14. O. Yumrutas and S.D. Saygideger, J. Med. Plants Res., 20, 2164 (2010).
  15. J.P. Rauha, S. Remes, M. Heinonen, A. Hopia, M. Kähkönen, T. Kujala, K. Pihlaja, H. Vuorela and P. Vuorela, Int. J. Food Microbiol., 56, 3 (2000); doi:10.1016/S0168-1605(00)00218-X.
  16. A. Basile, S. Sorbo, S. Giordano, L. Ricciardi, S. Ferrara, D. Montesano, R. Castaldo Cobianchi, M.L. Vuotto and L. Ferrara, Fitoterapia, 71, 110 (2000); doi:10.1016/S0367-326X(00)00185-4.
  17. H. Arima and G. Danno, Biosci. Biotechnol. Biochem., 66, 1727 (2002); doi:10.1271/bbb.66.1727.
  18. Y. Sato, S. Suzaki, T. Nishikawa, M. Kihara, H. Shibata and T. Higuti, J. Ethnopharmacol., 72, 483 (2000); doi:10.1016/S0378-8741(00)00265-8.
  19. A.J. Afolayan and J.J. Meyer, J. Ethnopharmacol., 57, 177 (1997); doi:10.1016/S0378-8741(97)00065-2.
  20. T.P.T. Cushnie, V.E.S. Hamilton and A.J. Lamb, Microbiol. Res., 158, 281 (2003); doi:10.1078/0944-5013-00206.
  21. S. Pepeljnjak and I. Kosalec, FEMS Microbiol. Lett., 240, 111 (2004); doi:10.1016/j.femsle.2004.09.018.
  22. H. Fukui, K. Goto and M. Tabata, Chem. Pharm. Bull. (Tokyo), 36, 4174 (1988); doi:10.1248/cpb.36.4174.
  23. C.D. Hufford and W.L. Lasswell, Lloydia, 41, 156 (1978).
  24. E.A. Bae, M.J. Han and D.H. Kim, Planta Med., 65, 442 (1999); doi:10.1055/s-2006-960805.
  25. D.H. Kim, E.A. Bae and M.J. Han, Biol. Pharm. Bull., 22, 422 (1999); doi:10.1248/bpb.22.422.
  26. P. Palacios, G. Gutkind, R.V. Rondina, R. de Torres and J.D. Coussio, Planta Med., 49, 128 (1983); doi:10.1055/s-2007-969832.
  27. F. Cottiglia, G. Loy, D. Garau, C. Floris, M. Casu, R. Pompei and L. Bonsignore, Phytomedicine, 8, 302 (2001); doi:10.1078/0944-7113-00036.
  28. H. Tsuchiya, M. Sato, T. Miyazaki, S. Fujiwara, S. Tanigaki, M. Ohyama, T. Tanaka and M. Iinuma, J. Ethnopharmacol., 50, 27 (1996); doi:10.1016/0378-8741(96)85514-0.
  29. Y. Sakagami, M. Mimura, K. Kajimura, H. Yokoyama, M. Iinuma, T. Tanaka and M. Ohyama, Lett. Appl. Microbiol., 27, 98 (1998); doi:10.1046/j.1472-765X.1998.00386.x.
  30. P.D. Stapleton, S. Shah, J.M.T. Hamilton-Miller, Y. Hara, Y. Nagaoka, A. Kumagai, S. Uesato and P.W. Taylor, Int. J. Antimicrob. Agents, 24, 374 (2004); doi:10.1016/j.ijantimicag.2004.03.024.
  31. T. Taguri, T. Tanaka and I. Kouno, Biol. Pharm. Bull., 27, 1965 (2004); doi:10.1248/bpb.27.1965.
  32. A.K. Bashir, A.A. Abdalla, I.A. Wasfi, E.S. Hassan, M.H. Amiri and T.A. Crabb, Int. J. Pharmacogn, 32, 366 (1994); doi:10.3109/13880209409083017.
  33. M.K. Sakar, R. Engelshowe and A.U. Tamer, Hacettepe Univ. Eczacilik Fakultesi Dergisi, 12, 59 (1992).
  34. L.E. Alcaraz, S.E. Blanco, O.N. Puig, F. Tomas and F.H. Ferretti, J. Theor. Biol., 205, 231 (2000); doi:10.1006/jtbi.2000.2062.
  35. M. Sato, S. Fujiwara, H. Tsuchiya, T. Fujii, M. Iinuma, H. Tosa and Y. Ohkawa, J. Ethnopharmacol., 54, 171 (1996); doi:10.1016/S0378-8741(96)01464-X.
  36. T.B. Ng, J.M. Ling, Z.T. Wang, J.N. Cai and G.J. Xu, Gen. Pharmacol., 27, 1237 (1996); doi:10.1016/0306-3623(95)02143-4.
  37. A.M. El-Lakany, M.S. Abdel-Kader, H.M. Hammoda, N.M. Ghazy and Z.F. Mahmoud, Pharmazie, 52, 78 (1997).
  38. D.K. Verma, S.K. Singh and V. Tripathi, Indian Drugs, 34, 32 (1997).
  39. S.G. Dastidar, A. Manna, K.A. Kumar, K. Mazumdar, N.K. Dutta, A.N. Chakrabarty, N. Motohashi and Y. Shirataki, Int. J. Antimicrob. Agents, 23, 99 (2004); doi:10.1016/j.ijantimicag.2003.06.003.
  40. M. Chacha, G. Bojase-Moleta and R.R. Majinda, Phytochemistry, 66, 99 (2005); doi:10.1016/j.phytochem.2004.10.013.
  41. K. Osawa, H. Yasuda, T. Maruyama, H. Morita, K. Takeya and H. Itokawa, Chem. Pharm. Bull. (Tokyo), 40, 2970 (1992); doi:10.1248/cpb.40.2970.
  42. W. Li, Y. Asada and T. Yoshikawa, Planta Med., 64, 746 (1998); doi:10.1055/s-2006-957571.
  43. K. Simin, Z. Ali, S.M. Khaliq-uz-Zaman and V.U. Ahmad, Nat. Prod. Lett., 16, 351 (2002); doi:10.1080/10575630290033114.
  44. S. Faizi and M. Ali, Planta Med., 65, 383 (1999); doi:10.1055/s-2006-960796.
  45. R.N. Yadava and K.I. Reddy, J. Asian Nat. Prod. Res., 1, 139 (1998); doi:10.1080/10286029808039856.
  46. J.E. Kelmanson, A.K. Jager and J. Van Staden, J. Ethnopharmacol., 69, 241 (2000); doi:10.1016/S0378-8741(99)00147-6.
  47. E.A. Palombo and S.J. Semple, J. Ethnopharmacol., 77, 151 (2001); doi:10.1016/S0378-8741(01)00290-2.
  48. B. Dulger and N. Hacioglu, Asian J. Chem., 20, 6577 (2008).
  49. B. Dulger, Pharm. Biol., 47, 467 (2009); doi:10.1080/13880200902824881.
  50. D. Arora and J. Kaur, Int. J. Antimicrob. Agents, 12, 257 (1999); doi:10.1016/S0924-8579(99)00074-6.
  51. S. Dupont, N. Caffin, B. Bhandari and G.A. Dykes, Food Control, 17, 929 (2006); doi:10.1016/j.foodcont.2005.06.005.
  52. S. Ozturk and S. Ercisli, Food Control, 18, 535 (2007); doi:10.1016/j.foodcont.2006.01.002.
  53. N.S. Al-Zoreky, Int. J. Food Microbiol., 134, 244 (2009); doi:10.1016/j.ijfoodmicro.2009.07.002.
  54. F. Bakkali, S. Averbeck, D. Averbeck and M. Idaomar, Food Chem. Toxicol., 46, 446 (2008); doi:10.1016/j.fct.2007.09.106.
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