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Novel Ferrocene Derivatives with Polycyclic Spatial Groups: Synthesis and Application
Corresponding Author(s) : N. Lekishvili
Asian Journal of Chemistry,
Vol. 26 No. 5 (2014): Vol 26 Issue 5
Abstract
New bioactive compounds for special purpose containing ferrocene, spatial polycyclic groups and transition metals have been synthesized and studied. By using of spectral (IR, UV), thermal (TG/DTA) analyses the structure and composition of the obtained compounds have been established. The ligand acts as a bidentate organometallic ligand (O-N). Theoretical bioscreening of obtained compounds have been carried out. Their antiviral, antimicrobial and antibacterial activities have been established. Application area of the obtained bioactive compounds has been recommended.
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References
A. Togni and R.L. Halterman, Metallocenes: Synthesis, Reactivity, Applications. Wiley-CH, Weinheim (1998).
A. Togni and T. Hayashi, Ferrocenes: Homogeneous Catalysis, Organic Synthesis, Materials Science, VCH, Weinheim (1995).
Y. Wang, Z.- Yang and B.- Wang, Transition Met. Chem, 30, 879 (2005); doi:10.1007/s11243-005-6166-9.
Sadiq-ur-Rehman, S. Ali, A. Badshah, M. Mazhar, X. Song, G. Eng and K.M. Khan, Synth. React. Inorg. Met. Org. Nano -Met. Chem., 34, 1379 (2004); doi:10.1081/SIM-200026257.
I.S. Morozov, V.I. Petrov and S.A. Sergeeva, Pharmacology of Adamantane, p. 320 (2001).
G.I. Danilenko and S.L. Rybalko, Chem. Pharm. J., 1, 24 (2000).
N.G. Artsimovich, T.S. Galushina and T.A. Fadeeva, Int. J. Immunorehabilitation, 2, 55 (2000).
M.J.S. Dewar, E.G. Zoebisch, E.F. Healy and J.J.P. Stewart, J. Am. Chem. Soc., 107, 3902 (1985); doi:10.1021/ja00299a024.
Zh. Gang, L. Feng, X. Jishan and M. Yongxiang, Polyhedron, 7, 393 (1988); doi:10.1016/S0277-5387(00)80488-X.
A. Sadim, A. Lagunin, D. Filiminov and V. Poroikov, Chem. Farm. J., 36, 21 (2002).