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Vol. 26 No. 6 (2014): Vol 26 Issue 6

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Synthesis of Homogeneously Dispersable Magnetite Nanoparticles via Size Control and Surface Modification for Hyperthermia Application

https://doi.org/10.14233/ajchem.2014.17316
Eun-Hee Lee
Nano-Convergence Intelligence Material Team, Korea Institute of Ceramic Engineering and Technology, 153-801 Seoul, Repubilic of Korea
Chang-Yeoul Kim
Nano-Convergence Intelligence Material Team, Korea Institute of Ceramic Engineering and Technology, 153-801 Seoul, Repubilic of Korea

Corresponding Author(s) : Chang-Yeoul Kim

cykim15@kicet.re.kr

Asian Journal of Chemistry, Vol. 26 No. 6 (2014): Vol 26 Issue 6

Abstract

Magnetite nanocrystals draw attractions of their applications for hyperthermia therapy in cancer killing by heating. These days, hyperthermia together with chemotherapy shows improved cancer treatment effects. The size control and surface modification of magnetite nanoparticles is very important for the application of biotechnology, because a magnetic property depends upon crystal sizes and a dispersability of magnetite changes with surface chemical state of the particles. We synthesized different-sized magnetite nanoparticles by changing the molar concentration of iron acetylacetonate and oleic acid-capped magnetite shows the hydrophobicity. To confer hydrophilic property, we modified the surface of magnetite nanoparticles with polyethylene glycol. We could present the possibilities of the dispersion of magnetite nanoparticles with different crystal sizes by surface modification with polyethylene glycol within phosphate buffer solution.

Keywords

Magnetite Hyperthermia Superparamagnetic Surface modification Size control
Lee, E.-H., & Kim, C.-Y. (2014). Synthesis of Homogeneously Dispersable Magnetite Nanoparticles via Size Control and Surface Modification for Hyperthermia Application. Asian Journal of Chemistry, 26(6), 1661–1666. https://doi.org/10.14233/ajchem.2014.17316
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