Asperal: A New Clerodane Diterpene from Sonchus asper

Ihsan Ullah Khan; Farman Ullah Khan; Javid Hussain; Syed Badshah; Nawshad Muhammad; Rahmat Ali Khan; Chong Fai Kait; Mian Abdul Ali; Hidayatullah Khan; Muhammad Waqar Aslam; Iqbal Hussain

doi:10.14233/ajchem.2014.16008

Issue

Vol. 26 No. 9 (2014): Vol 26 Issue 9

Issue Published : April 28, 2014

This work is licensed under a Creative Commons Attribution 4.0 International License.

Asperal: A New Clerodane Diterpene from Sonchus asper

https://doi.org/10.14233/ajchem.2014.16008

Ihsan Ullah Khan

Department of Fundamental and Applied Sciences, University of Technology PETRONAS, Perak, Malaysia

Farman Ullah Khan

Department of Chemistry, University of Science and Technology, Bannu-28100, KPK, Pakistan

Javid Hussain

Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Nizwa, Oman

Syed Badshah

Department of Chemistry, Gomal University, D.I. Khan, KPK, Pakistan

Nawshad Muhammad

Interdisciplinary Research Centerin Biomedical Materials, COMSATS Institute of Information Technology, Lahore, Pakistan

Rahmat Ali Khan

Department of Biotechnology, University of Science and Technology, Bannu-28100, KPK, Pakistan

Chong Fai Kait

Department of Fundamental and Applied Sciences, University of Technology PETRONAS, Perak, Malaysia

Mian Abdul Ali

Department of Chemistry, University of Science and Technology, Bannu-28100, KPK, Pakistan

Hidayatullah Khan

Department of Biotechnology, University of Science and Technology, Bannu-28100, KPK, Pakistan

Muhammad Waqar Aslam

Department of Chemistry, University of Science and Technology, Bannu-28100, KPK, Pakistan

Iqbal Hussain

Department of Chemistry, Islamia College University, Peshawar, KPK, Pakistan

Corresponding Author(s) : Farman Ullah Khan

farmandphil@yahoo.com ;nawashadchemist@yahoo.com

Asian Journal of Chemistry, Vol. 26 No. 9 (2014): Vol 26 Issue 9
Article Published : April 29, 2014

Abstract

A new diterpenoid asperal (1) has been isolated from the chloroform soluble fraction of Sonchus asper along with two known compounds, emodin (2) and methyl-(3,8-di-hydroxy-6-methyl-9-oxo-9H-xanthene)-1-carboxylate (3) which were isolated for the first time from this species. The structures of the isolated compounds were assigned on the basis of ID and 2D NMR spectral analysis and by comparison with the reported data.

Keywords

Sonchus asper Asteraceae Clerodane diterpene

Ullah Khan, I., Ullah Khan, F., Hussain, J., Badshah, S., Muhammad, N., Ali Khan, R., … Hussain, I. (2014). Asperal: A New Clerodane Diterpene from Sonchus asper. Asian Journal of Chemistry, 26(9), 2699–2701. https://doi.org/10.14233/ajchem.2014.16008

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References

N.D. Rivera and D.C.C. Oben, Ethnopharmacology of Murcia (SE Spain), Conference Internationale Ethnomedecine, Heidelb2e.4rg-2, (1993) 7.
A.M. Sammon, Cancer, 83, 405 (1998); doi:10.1002/(SICI)1097-0142(19980801)83:3<405::AID-CNCR6>3.0.CO;2-N.
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K. Hussain and A. Shahazad, Ethnobot. Leaflets, 12, 29 (2008).
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Q. Zabihullah, A. Rashid and N. Akhter, Pak. J. Plant Sciences, 12, 115 (2006).
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G. Jan, M.A. Khan and F. Gul, Ethnobot. Leaflets, 13, 1029 (2009).
S. Manez, M.C. Recio, R.M. Giner, M.J. Sanz, M.C. Terencio, J.B. Peris, G. Stubing and J.L. Rios, Biochem. Syst. Ecol., 22, 297 (1994); doi:10.1016/0305-1978(94)90104-X.
A.M. Helal, N. Nakamura, H. El-Askary and M. Hattori, Phytochemistry, 53, 473 (2000); doi:10.1016/S0031-9422(99)00516-6.
R.A. Spanevello and A.J. Vila, Phytochemistry, 35, 537 (1994); doi:10.1016/S0031-9422(00)94797-6.
F. Nagashima and Y. Asakawa, Phytochemistry, 29, 3229 (1990); doi:10.1016/0031-9422(90)80190-R.
V.U. Ahmad, U. Farooq, J. Hussain, F. Ullah, S.A. Nawaz and M.I. Choudhary, Chem. Pharm. Bull. (Tokyo), 52, 441 (2004); doi:10.1248/cpb.52.441.
V.U. Ahmad, A. Khan, U. Farooq, F. Kousar, S. S. Khan and J. Hussain, J. Asian Nat. Prod. Res., 9, 91 (2007); doi:10.1080/10286020500478740.
J.R. Dai, R. Suttisri, E. Bordas, D.D. Soejarto and A.D. Kinghorn, Phytochemistry, 34, 1087 (1993); doi:10.1016/S0031-9422(00)90720-9.
J. Hussain, N. Jamila, F. Ullah Khan, K. Prasad Devkota, M.R. Shah and S. Anwar, Magn. Reson. Chem., 47, 625 (2009); doi:10.1002/mrc.2439.

References

N.D. Rivera and D.C.C. Oben, Ethnopharmacology of Murcia (SE Spain), Conference Internationale Ethnomedecine, Heidelb2e.4rg-2, (1993) 7.

A.M. Sammon, Cancer, 83, 405 (1998); doi:10.1002/(SICI)1097-0142(19980801)83:3<405::AID-CNCR6>3.0.CO;2-N.

B. Thomson and I.A. Shaw, Asian Pac. J. Cancer Prev., 3, 319 (2002).

K. Hussain and A. Shahazad, Ethnobot. Leaflets, 12, 29 (2008).

D.K. Koche, R.P. Shirsat, S. Imran, M. Nafees, A.K. Zingare and K.A. Donode, Ethnobot. Leaflets, 12, 532 (2008).

M. Sabeen and A.A. Ahmad, Ethnobot. Leaflets, 13, 810 (2009).

Q. Zabihullah, A. Rashid and N. Akhter, Pak. J. Plant Sciences, 12, 115 (2006).

P.G. Kareru, G.M. Kenji, A.N. Gachanja, J.M. Keriko, J.M. Keriko and G. Mungai, Afr. J. Tradit. Complement. Altern. Med., 4, 75 (2007); doi:10.4314/ajtcam.v4i1.31193.

G. Jan, M.A. Khan and F. Gul, Ethnobot. Leaflets, 13, 1029 (2009).

S. Manez, M.C. Recio, R.M. Giner, M.J. Sanz, M.C. Terencio, J.B. Peris, G. Stubing and J.L. Rios, Biochem. Syst. Ecol., 22, 297 (1994); doi:10.1016/0305-1978(94)90104-X.

A.M. Helal, N. Nakamura, H. El-Askary and M. Hattori, Phytochemistry, 53, 473 (2000); doi:10.1016/S0031-9422(99)00516-6.

R.A. Spanevello and A.J. Vila, Phytochemistry, 35, 537 (1994); doi:10.1016/S0031-9422(00)94797-6.

F. Nagashima and Y. Asakawa, Phytochemistry, 29, 3229 (1990); doi:10.1016/0031-9422(90)80190-R.

V.U. Ahmad, U. Farooq, J. Hussain, F. Ullah, S.A. Nawaz and M.I. Choudhary, Chem. Pharm. Bull. (Tokyo), 52, 441 (2004); doi:10.1248/cpb.52.441.

V.U. Ahmad, A. Khan, U. Farooq, F. Kousar, S. S. Khan and J. Hussain, J. Asian Nat. Prod. Res., 9, 91 (2007); doi:10.1080/10286020500478740.

J.R. Dai, R. Suttisri, E. Bordas, D.D. Soejarto and A.D. Kinghorn, Phytochemistry, 34, 1087 (1993); doi:10.1016/S0031-9422(00)90720-9.

J. Hussain, N. Jamila, F. Ullah Khan, K. Prasad Devkota, M.R. Shah and S. Anwar, Magn. Reson. Chem., 47, 625 (2009); doi:10.1002/mrc.2439.

Issue

Vol. 26 No. 9 (2014): Vol 26 Issue 9

Asperal: A New Clerodane Diterpene from Sonchus asper

Corresponding Author(s) : Farman Ullah Khan

Abstract

Keywords

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