Issue

Vol. 31 No. 11 (2019): Vol 31 Issue 11

Copyright (c) 2019 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Adsorption Capacity and Selectivity of Molecularly Imprinted Polymers towards β-Sitosterol

https://doi.org/10.14233/ajchem.2019.22141
St. Fauziah
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, Indonesia
N.H. Soekamto
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, Indonesia
P. Budi
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, Indonesia
P. Taba
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, Indonesia

Corresponding Author(s) : St. Fauziah

stfauziah_as@yahoo.co.id

Asian Journal of Chemistry, Vol. 31 No. 11 (2019): Vol 31 Issue 11

Abstract

Molecularly imprinted polymers (MIP) as an adsorbent has been synthesized using β-sitosterol as molecule template on free radical polymerization reaction. The capacity and selectivity of the adsorption from MIP to β-sitosterol was studied in this study. The β-sitosterol concentration in the adsorption-desorption test and the MIP selectivity test were analyzed by UV-visible and HPLC. The MIP obtained from the synthesis results in a high adsorption capacity. Based on the Freundlich adsorption isothermal equation, the adsorption capacity (k) was found to be 1.24 mg/g. The MIP can adsorb 100 % β-sitosterol while cholesterol was only 3 %. The MIP is most selective to β-sitosterol, therefore, has high potential to apply as adsorbent at solid phase extraction method to isolate β-sitosterol from sample extract.

Keywords

Synthesis Molecularly imprinted polymers Selectivity β-Sitosterol
Fauziah, S., Soekamto, N., Budi, P., & Taba, P. (2019). Adsorption Capacity and Selectivity of Molecularly Imprinted Polymers towards β-Sitosterol. Asian Journal of Chemistry, 31(11), 2527–2531. https://doi.org/10.14233/ajchem.2019.22141
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. S. Otles and C. Kartal, Acta Sci. Pol. Technol. Aliment., 15, 5 (2016); https://doi.org/10.17306/J.AFS.2016.1.1.
  2. T. Zhu, C. Yoon and K. Row, Chin. J. Chem., 29, 1246 (2011); https://doi.org/10.1002/cjoc.201190231.
  3. S. Xu, J. Li and L. Chen, Talanta, 85, 282 (2011); https://doi.org/10.1016/j.talanta.2011.03.060.
  4. H. Surikumaran, S. Mohamad and N. Sarih, Int. J. Mol. Sci., 15, 6111 (2014); https://doi.org/10.3390/ijms15046111.
  5. M.-J. Syu, J.-H. Deng, Y.-M. Nian, T.-C. Chiu and A.-H. Wu, Biomaterials, 26, 4684 (2005); https://doi.org/10.1016/j.biomaterials.2004.11.024.
  6. H.Y. Wang, J.G. Jiang, L.Y. Ma and Y.L. Pang, React. Funct. Polym., 66, 1081 (2006); https://doi.org/10.1016/j.reactfunctpolym.2006.01.022.
  7. H. Yan, R. Wang, Y. Han and S. Liu, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 900, 18 (2012); https://doi.org/10.1016/j.jchromb.2012.05.021.
  8. J. Rene, P. Adhikar and R.L. Bakal, Asian J. Pharm. Technol. Innov., 3, 75 (2015).
  9. K. Matsumoto, B.D.B. Tiu, A. Kawamura, R.C. Advincula and T. Miyata, Polym. J., 48, 525 (2016); https://doi.org/10.1038/pj.2016.23.
  10. H. Yavuz, V. Karakoc, D. Turkmen, R. Say and A. Denizli, Int. J. Biol. Macromol., 41, 8 (2007); https://doi.org/10.1016/j.ijbiomac.2006.11.011.
  11. L. Chen, X. Wang, W. Lu, X. Wu and J. Li, Chem. Soc. Rev., 45, 2137 (2016); https://doi.org/10.1039/C6CS00061D.
  12. X. Song, J. Li, J. Wang and L. Chen, Talanta, 80, 694 (2009); https://doi.org/10.1016/j.talanta.2009.07.051.
  13. E. Blahova, J. Lehotay and I. Skaèáni, J. Liq. Chromatogr. Relat. Technol., 27, 2715 (2004); https://doi.org/10.1081/JLC-200029276.
  14. M. Li, L. Zhang, Z. Meng, Z. Wang and H. Wu, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 878, 2333 (2010); https://doi.org/10.1016/j.jchromb.2010.07.003.
  15. H. Zhang, T. Song, F. Zong, T. Chen and C. Pan, Int. J. Mol. Sci., 9, 998 (2008).
  16. M. Biesaga, A. Jankowska and K. Pyrzynska, Mikrochim. Acta, 150, 317 (2005); https://doi.org/10.1007/s00604-005-0359-y.
  17. R. Weiss, A. Molinelli, M. Jakusch and B. Mizaikoff, Bioseparation, 10, 379 (2001); https://doi.org/10.1023/A:1021554106297.
  18. F. Omidi, M. Behbahani, H. Sadeghi Abandansari, A. Sedighi and S.J. Shahtaheri, J. Environ. Health Sci. Eng., 12, 137 (2014); https://doi.org/10.1186/s40201-014-0137-z.
  19. N.H. Soekamto, St. Fauziah, P. Taba and M.B. Amran, IOP Conf. Series: Mater. Sci. Eng., 188, 012048 (2017); https://doi.org/10.1088/1757-899X/188/1/012048.
  20. R. Walsh, Ph.D. Thesis, Pharmaceutical and Molecular Biotechnology Research Centre Waterford Institute of Technology, Waterford: Ireland (2010).
  21. A. Beltran, F. Borrull, R.M. Marcé and P.A.G. Cormack, TrAC Trends Anal. Chem., 29, 1363 (2010); https://doi.org/10.1016/j.trac.2010.07.020.
  22. Q. Zhu, J. Tang, J. Dai, X. Gu and S. Chen, J. Appl. Polym. Sci., 104, 1551 (2007); https://doi.org/10.1002/app.25564.
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 3