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Vol. 26 No. 12 (2014): Vol 26 Issue 12

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Synthesis and Controlled Release of Vitamin C Intercalated Zn/Al Layered Double Hydroxide

https://doi.org/10.14233/ajchem.2014.15955
Xiaorui Gao
College of Science, Hebei University of Engineering, Handan 056038, P.R. China
Lixu Lei
School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P.R. China
Le Chen
School of Chemistry and Chemical Engineering, Changzhou University, Changzhou 213164, P.R. China
Yuqiao Wang
2School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P.R. China
Leqin He
College of Science, Hebei University of Engineering, Handan 056038, P.R. China
Yiwei Lian
College of Science, Hebei University of Engineering, Handan 056038, P.R. China

Corresponding Author(s) : Xiaorui Gao

gxr_1320@sina.com

Asian Journal of Chemistry, Vol. 26 No. 12 (2014): Vol 26 Issue 12

Abstract

A drug-inorganic composite involving vitamin C intercalated in Zn-Al layered double hydroxides has been synthesized by a coprecipitation method. Powder X-ray diffraction, fourier transform infrared, elemental analysis, thermogravimetric analysis and UV-visible absorption spectroscopy indicate a successful intercalation of vitamin C into the interlayer galleries of the layered double hydroxides host and the loading of vitamin C in the layered double hydroxides is 84 %. Studies of vitamin C release from the layered double hydroxides in deionized water and in aqueous CO32- solutions imply that Zn2Al-vitamin-C layered double hydroxides is a better controlled release system. Analysis of the release profiles using a number of kinetic models suggests a solution-dependent release mechanism and a combination process of diffusion-controlled and ion exchange deintercalation mechanisms in deionised water, but an ion exchange process in CO32- solution.

Keywords

Layered double hydroxide Controlled release Vitamin C Coprecipitation
Gao, X., Lei, L., Chen, L., Wang, Y., He, L., & Lian, Y. (2014). Synthesis and Controlled Release of Vitamin C Intercalated Zn/Al Layered Double Hydroxide. Asian Journal of Chemistry, 26(12), 3471–3476. https://doi.org/10.14233/ajchem.2014.15955
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