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Green Synthesis of 6-[2-Aminothiazol-4-yl]-2-furylchromone
Corresponding Author(s) : Vinay Prabha Sharma
Asian Journal of Chemistry,
Vol. 26 No. 13 (2014): Vol 26 Issue 13
Abstract
Synthesis of 2-aminothiazoles through Hantzsch method involves the use of bromine. An 2-aminothiazole system 6-[2-aminothiazol-4-yl]-2-furylchromone has been synthesized green chemically from 6-chloroacetyl-2-furylchromone and 6-acetyl-2-furylchromone during present study. The structures of new compounds were elucidated on the basis of IR and PMR-spectra.
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- A.A. Zagade and G.P. Senthi Kumar, Der Pharma Chem., 3, 523 (2011).
- Q. Zhao, C. Shen, H. Zheng, J. Zhang and P. Zhang, Carbohydr. Res., 345, 437 (2010); doi:10.1016/j.carres.2009.11.032.
- T.F.A.F. Reji, S.K.C. Devi, K.K. Thomas, K. G. Sreeja Lakshmi, S.L. Manju and K. N. Rajasekharan, Indian J. Chem., 47B, 1145 (2008).
- G.M. Malik and S.K. Zadafiya, Der Chem. Sinica, 1, 15 (2010).
- S.K. Sahu, S.K. Mishra, N.K. Mohanta, P.K. Panda and A.M. Azam, Indian J. Pharm. Sci., 69, 689 (2007); doi:10.4103/0250-474X.38480.
- S. K. Pattan, M. Shamrez Ali, J. S. Pattan, S. S. Purohit, V.V.K. Reddy and B.R. Nataraj, Indian J. Chem., 45B, 1929 (2006).
- S.R. Pattan, V.V. Pawar, P.D. Khada, N.S. Desai, A.R. Bhat and A.D. Taranalli, Indian Drugs, 44, 253 (2007).
- S.N. Sawhney, G.S. Dhindsa and S.P. Singh, Indian J. Chem., 22B, 1044 (1983).
- S. Pattan, K. Alagwadi, A. Bhat, V. Reddy, J. Pattan, A. Khada and K. Bhat, Indian Drugs, 45, 532 (2007).
- A. Andreani, M. Granaiola, A. Leoni, A. Locatelli, R. Morigi and M. Rambaldi, Eur. J. Med. Chem., 36, 743 (2001); doi:10.1016/S0223-5234(01)01266-1.
- C.-L. Liu, Z.-M. Li and B. Zhong, J. Fluor. Chem., 125, 1287 (2004); doi:10.1016/j.jfluchem.2004.03.006.
- Y. Chen, H.-R. Liu, H.-S. Liu, M. Cheng, P. Xia, K. Qian, P.-C. Wu, C.-Y. Lai, Y. Xia, Z.-Y. Yang, S.L. Morris-Natschke and K.-H. Lee, Eur. J. Med. Chem., 49, 74 (2012); doi:10.1016/j.ejmech.2011.12.025.
- G. Valdameri, E. Genoux-Bastide, B. Peres, C. Gauthier, J. Guitton, R. Terreux, S.M.B. Winnischofer, M.E.M. Rocha, A. Boumendjel and A. Di Pietro, J. Med. Chem., 55, 966 (2012); doi:10.1021/jm201404w.
- M.A. Arai, Chem. Pharm. Bull. (Tokyo), 59, 417 (2011); doi:10.1248/cpb.59.417.
- V.P. Sharma, P. Kumar and M. Sharma, Asian J. Chem., 23, 4616 (2011).
- M.A. Ibrahim, T.E. Youssef, A. Alnamer and Y.A. Gabr, ARKIVOC, 98 (2010); doi:10.3998/ark.5550190.0011.103.
- S.S. Ibrahim, H.A. Allimony, A.M. Abdel Halim and M.A. Ibrahim, ARKIVOC, 28 (2009); doi:10.3998/ark.5550190.0010.e03.
- M.C. Patel, N.C. Nilesh and D.P. Rajani, Der Pharma Chem., 3, 422 (2011).
- D.P. Sarbaggya, K. Rangachari, A.K.D. Mazumdar and K.D. Banerji, J. Indian Chem. Soc., 58, 196 (1981).
- (a) O. Prakesh, A. Kumar and S. P. Singh, J. Indian Chem. Soc., 80, 1035 (2003); (b) O.V. Singh, R.P. Kapoor, R. Kumar and V.P. Sharma, Indian J. Heterocycl. Chem., 18, 125 (2008).
- (a) R.M. Dodson and L.C. King, J. Am. Chem. Soc., 67, 2242 (1945); doi:10.1021/ja01228a059.; (b) L.C. King and I. Ryden, J. Am. Chem. Soc., 69, 1813 (1947); doi:10.1021/ja01199a072.; (c) L.C. King and R.J. Hlavacek, J. Am. Chem. Soc., 72, 3722 (1950); doi:10.1021/ja01164a110.
References
A.A. Zagade and G.P. Senthi Kumar, Der Pharma Chem., 3, 523 (2011).
Q. Zhao, C. Shen, H. Zheng, J. Zhang and P. Zhang, Carbohydr. Res., 345, 437 (2010); doi:10.1016/j.carres.2009.11.032.
T.F.A.F. Reji, S.K.C. Devi, K.K. Thomas, K. G. Sreeja Lakshmi, S.L. Manju and K. N. Rajasekharan, Indian J. Chem., 47B, 1145 (2008).
G.M. Malik and S.K. Zadafiya, Der Chem. Sinica, 1, 15 (2010).
S.K. Sahu, S.K. Mishra, N.K. Mohanta, P.K. Panda and A.M. Azam, Indian J. Pharm. Sci., 69, 689 (2007); doi:10.4103/0250-474X.38480.
S. K. Pattan, M. Shamrez Ali, J. S. Pattan, S. S. Purohit, V.V.K. Reddy and B.R. Nataraj, Indian J. Chem., 45B, 1929 (2006).
S.R. Pattan, V.V. Pawar, P.D. Khada, N.S. Desai, A.R. Bhat and A.D. Taranalli, Indian Drugs, 44, 253 (2007).
S.N. Sawhney, G.S. Dhindsa and S.P. Singh, Indian J. Chem., 22B, 1044 (1983).
S. Pattan, K. Alagwadi, A. Bhat, V. Reddy, J. Pattan, A. Khada and K. Bhat, Indian Drugs, 45, 532 (2007).
A. Andreani, M. Granaiola, A. Leoni, A. Locatelli, R. Morigi and M. Rambaldi, Eur. J. Med. Chem., 36, 743 (2001); doi:10.1016/S0223-5234(01)01266-1.
C.-L. Liu, Z.-M. Li and B. Zhong, J. Fluor. Chem., 125, 1287 (2004); doi:10.1016/j.jfluchem.2004.03.006.
Y. Chen, H.-R. Liu, H.-S. Liu, M. Cheng, P. Xia, K. Qian, P.-C. Wu, C.-Y. Lai, Y. Xia, Z.-Y. Yang, S.L. Morris-Natschke and K.-H. Lee, Eur. J. Med. Chem., 49, 74 (2012); doi:10.1016/j.ejmech.2011.12.025.
G. Valdameri, E. Genoux-Bastide, B. Peres, C. Gauthier, J. Guitton, R. Terreux, S.M.B. Winnischofer, M.E.M. Rocha, A. Boumendjel and A. Di Pietro, J. Med. Chem., 55, 966 (2012); doi:10.1021/jm201404w.
M.A. Arai, Chem. Pharm. Bull. (Tokyo), 59, 417 (2011); doi:10.1248/cpb.59.417.
V.P. Sharma, P. Kumar and M. Sharma, Asian J. Chem., 23, 4616 (2011).
M.A. Ibrahim, T.E. Youssef, A. Alnamer and Y.A. Gabr, ARKIVOC, 98 (2010); doi:10.3998/ark.5550190.0011.103.
S.S. Ibrahim, H.A. Allimony, A.M. Abdel Halim and M.A. Ibrahim, ARKIVOC, 28 (2009); doi:10.3998/ark.5550190.0010.e03.
M.C. Patel, N.C. Nilesh and D.P. Rajani, Der Pharma Chem., 3, 422 (2011).
D.P. Sarbaggya, K. Rangachari, A.K.D. Mazumdar and K.D. Banerji, J. Indian Chem. Soc., 58, 196 (1981).
(a) O. Prakesh, A. Kumar and S. P. Singh, J. Indian Chem. Soc., 80, 1035 (2003); (b) O.V. Singh, R.P. Kapoor, R. Kumar and V.P. Sharma, Indian J. Heterocycl. Chem., 18, 125 (2008).
(a) R.M. Dodson and L.C. King, J. Am. Chem. Soc., 67, 2242 (1945); doi:10.1021/ja01228a059.; (b) L.C. King and I. Ryden, J. Am. Chem. Soc., 69, 1813 (1947); doi:10.1021/ja01199a072.; (c) L.C. King and R.J. Hlavacek, J. Am. Chem. Soc., 72, 3722 (1950); doi:10.1021/ja01164a110.