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A New Diphenylethylene from Arundina graminifolia and Its Cytotoxicity
Corresponding Author(s) : Yinhai Ma
Asian Journal of Chemistry,
Vol. 26 No. 13 (2014): Vol 26 Issue 13
Abstract
A new diphenylethylenes, gramniphenol J (1), was isolated from Arundina graminifolia. Its structure was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compound 1 was evaluated for its cytotoxicity against five human tumor cell lines and showed cytotoxicity against PC3 and SHSY5Y cells with IC50 values of 8.2 and 7.6 μM.
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- X.Q. Chen and S.W. Gale, Floral of China; Science Press: Beijing, Vol. 25, pp. 315 (2009).
- Anonymous, Chinese Medicinal Herbs: Vol. Dai Yao; Shanghai Science and Technology Press: Shanghai, pp. 116 (2005).
- M.F. Liu, Y. Han, D.M. Xing, Y. Shi, L.Z. Xu, L.J. Du and Y. Ding, J. Asian Nat. Prod. Res., 6, 229 (2004); doi:10.1080/10286020310001653219.
- M.F. Liu, H.R. Lv and Y. Ding, J. Chin. Mater. Med., 37, 66 (2012).
- M.F. Liu, Y. Han, D.M. Xing, W. Wang, L.Z. Xu, L.J. Du and Y. Ding, J. Asian Nat. Prod. Res., 7, 767 (2005); doi:10.1080/102860204100016890181.
- M.F. Liu, D.M. Zhang and Y. Ding, J. Chin. Mater. Med., 30, 353 (2005).
- Q.F. Hu, B. Zhou, J.M. Huang, X.M. Gao, L.D. Shu, G.Y. Yang and C.T. Che, J. Nat. Prod., 76, 292 (2013); doi:10.1021/np300727f.
- X.M. Gao, L.Y. Yang, Y.Q. Shen, L.D. Shu, X.M. Li and Q.F. Hu, Bull. Korean Chem. Soc., 33, 2447 (2012); doi:10.5012/bkcs.2012.33.7.2447.
- G.R. Pettit, A. Numata, C. Iwamoto, Y. Usami, T. Yamada, H. Ohishi and G.M. Cragg, J. Nat. Prod., 69, 323 (2006); doi:10.1021/np058075+.
- A. Kovács, A. Vasas and J. Hohmann, Phytochemistry, 69, 1084 (2008); doi:10.1016/j.phytochem.2007.12.005.
- K. Xiao, H.J. Zhang, L.J. Xuan, J. Zhang, Y.-M. Xu and D.-L. Bai, Stud. Nat. Prod. Chem., 34, 453 (2008); doi:10.1016/S1572-5995(08)80032-4.
- M.A. Zaki, P. Balachandran, S. Khan, M. Wang, R. Mohammed, M.H. Hetta, D.S. Pasco and I. Muhammad, J. Nat. Prod., 76, 679 (2013); doi:10.1021/np300893n.
- T. Mosmann, J. Immunol. Methods, 65, 55 (1983); doi:10.1016/0022-1759(83)90303-4.
References
X.Q. Chen and S.W. Gale, Floral of China; Science Press: Beijing, Vol. 25, pp. 315 (2009).
Anonymous, Chinese Medicinal Herbs: Vol. Dai Yao; Shanghai Science and Technology Press: Shanghai, pp. 116 (2005).
M.F. Liu, Y. Han, D.M. Xing, Y. Shi, L.Z. Xu, L.J. Du and Y. Ding, J. Asian Nat. Prod. Res., 6, 229 (2004); doi:10.1080/10286020310001653219.
M.F. Liu, H.R. Lv and Y. Ding, J. Chin. Mater. Med., 37, 66 (2012).
M.F. Liu, Y. Han, D.M. Xing, W. Wang, L.Z. Xu, L.J. Du and Y. Ding, J. Asian Nat. Prod. Res., 7, 767 (2005); doi:10.1080/102860204100016890181.
M.F. Liu, D.M. Zhang and Y. Ding, J. Chin. Mater. Med., 30, 353 (2005).
Q.F. Hu, B. Zhou, J.M. Huang, X.M. Gao, L.D. Shu, G.Y. Yang and C.T. Che, J. Nat. Prod., 76, 292 (2013); doi:10.1021/np300727f.
X.M. Gao, L.Y. Yang, Y.Q. Shen, L.D. Shu, X.M. Li and Q.F. Hu, Bull. Korean Chem. Soc., 33, 2447 (2012); doi:10.5012/bkcs.2012.33.7.2447.
G.R. Pettit, A. Numata, C. Iwamoto, Y. Usami, T. Yamada, H. Ohishi and G.M. Cragg, J. Nat. Prod., 69, 323 (2006); doi:10.1021/np058075+.
A. Kovács, A. Vasas and J. Hohmann, Phytochemistry, 69, 1084 (2008); doi:10.1016/j.phytochem.2007.12.005.
K. Xiao, H.J. Zhang, L.J. Xuan, J. Zhang, Y.-M. Xu and D.-L. Bai, Stud. Nat. Prod. Chem., 34, 453 (2008); doi:10.1016/S1572-5995(08)80032-4.
M.A. Zaki, P. Balachandran, S. Khan, M. Wang, R. Mohammed, M.H. Hetta, D.S. Pasco and I. Muhammad, J. Nat. Prod., 76, 679 (2013); doi:10.1021/np300893n.
T. Mosmann, J. Immunol. Methods, 65, 55 (1983); doi:10.1016/0022-1759(83)90303-4.