Copyright (c) 2014 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Paper-Based Microfluidic Device for Determination of Nitrite in Pickled Vegetables
Corresponding Author(s) : Longfei Cai
Asian Journal of Chemistry,
Vol. 26 No. 14 (2014): Vol 26 Issue 14
Abstract
Nitrite is a carcinogen which has been detected in various foods including pickled vegetables, cured meat and fish products. Development of cost effective, simple and easy-to- use method for determination of nitrite in foods is thus highly desirable, especially for those foods that traditionally contains high contents of nitrite. In this work, a paper-based microfluidic analytical method was proposed for the determination of nitrite in pickled vegetables. Determination of nitrite was based on the chromogenic reaction between nitrite and mixed chromogenic reagents on a paper-based microfluidic device. This method offers advantages of easy fabrication, low reagents/sample consumption, ease of use, fast analysis speed and low cost, which may have potential in food safety testing for household use.
Keywords
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
- I.T. Bae, R.L. Barbour and D.A. Scherson, Anal. Chem., 69, 249 (1997); doi:10.1021/ac960769n.
- I.M.P.L.V.O. Ferreira, J.L.F.C. Lima, M.C.B.S.M. Montenegro, R.P. Olmos and A. Rios, Analyst, 121, 1393 (1996); doi:10.1039/AN9962101393.
- Y.X. Guo, Q.F. Zhang, X.C. Shangguang and G.D. Zhen, Spectrochim. Acta A, 101, 107 (2013); doi:10.1016/j.saa.2012.09.083.
- N.Q. Jie, Z.K. Si, J.H. Yang, Z. Miao, X.R. Huang, Q. Zhang and Z.Q. Song, Microchem. J., 55, 351 (1997); doi:10.1006/mchj.1996.1314.
- D.Y. He, Z.J. Zhang, Y. Huang and Y.F. Hu, Food Chem., 101, 667 (2007); doi:10.1016/j.foodchem.2006.02.024.
- X.H. Chen, C.M. Ruan, J.L. Kong and J.Q. Deng, Anal. Chim. Acta, 382, 189 (1999); doi:10.1016/S0003-2670(98)00791-0.
- B. Unnikrishnan, P.L. Ru, S.M. Chen and V. Mani, Sens. Actuators B, 177, 887 (2013); doi:10.1016/j.snb.2012.11.102.
- S. Yurchenko and U. Mölder, Food Chem., 96, 325 (2006); doi:10.1016/j.foodchem.2005.04.009.
- J. Kieber and P.J. Seaton, Anal. Chem., 67, 3261 (1995); doi:10.1021/ac00114a024.
- X. Wang, E. Adams and A. Van Schepdael, Talanta, 97, 142 (2012); doi:10.1016/j.talanta.2012.04.008.
- L.-F. Cai, Y. Zhu, G.-S. Du and Q. Fang, Anal. Chem., 84, 446 (2012); doi:10.1021/ac2029198.
- G.M. Walker, J.Q. Sai, A. Richmond, M. Stremler, C.Y. Chung and J.P. Wikswo, Lab Chip, 5, 611 (2005); doi:10.1039/b417245k.
- S. Gotz, T. Revermann and U. Karst, Lab Chip, 7, 93 (2007); doi:10.1039/b609739a.
- A. Huebner, L.F. Olguin, D. Bratton, G. Whyte, W.T.S. Huck, A.J. de Mello, J.B. Edel, C. Abell and F. Hollfelder, Anal. Chem., 80, 3890 (2008); doi:10.1021/ac800338z.
- Z.J. Jia, Q. Fang and Z.L. Fang, Anal. Chem., 76, 5597 (2004); doi:10.1021/ac0494477.
- G.M. Whitesides, E. Ostuni, S. Takayama, X.Y. Jiang and D.E. Ingber, Annu. Rev. Biomed. Eng., 3, 335 (2001); doi:10.1146/annurev.bioeng.3.1.335.
- C.G. Khan Malek, Anal. Bioanal. Chem., 385, 1362 (2006); doi:10.1007/s00216-006-0517-z.
- A.W. Martinez, S.T. Phillips, M.J. Butte and G.M. Whitesides, Angew. Chem. Int. Ed., 46, 1318 (2007); doi:10.1002/anie.200603817.
- K.M. Schilling, A.L. Lepore, J.A. Kurian and A.W. Martinez, Anal. Chem., 84, 1579 (2012); doi:10.1021/ac202837s.
- X. Li, J.F. Tian, G. Garnier and W. Shen, Colloids Surf. B, 76, 564 (2010); doi:10.1016/j.colsurfb.2009.12.023.
- Y. Lu, W.W. Shi, L. Jiang, J.H. Qin and B.C. Lin, Electrophoresis, 30, 1497 (2009); doi:10.1002/elps.200800563.
- L.F. Cai, Y.Y. Wu, C.X. Xu and Z.F. Chen, J. Chem. Educ., 90, 232 (2013); doi:10.1021/ed300385j.
- Z. Kang, Food Analysis and Detection, Light Industry Press, Beijing, China (2006).
References
I.T. Bae, R.L. Barbour and D.A. Scherson, Anal. Chem., 69, 249 (1997); doi:10.1021/ac960769n.
I.M.P.L.V.O. Ferreira, J.L.F.C. Lima, M.C.B.S.M. Montenegro, R.P. Olmos and A. Rios, Analyst, 121, 1393 (1996); doi:10.1039/AN9962101393.
Y.X. Guo, Q.F. Zhang, X.C. Shangguang and G.D. Zhen, Spectrochim. Acta A, 101, 107 (2013); doi:10.1016/j.saa.2012.09.083.
N.Q. Jie, Z.K. Si, J.H. Yang, Z. Miao, X.R. Huang, Q. Zhang and Z.Q. Song, Microchem. J., 55, 351 (1997); doi:10.1006/mchj.1996.1314.
D.Y. He, Z.J. Zhang, Y. Huang and Y.F. Hu, Food Chem., 101, 667 (2007); doi:10.1016/j.foodchem.2006.02.024.
X.H. Chen, C.M. Ruan, J.L. Kong and J.Q. Deng, Anal. Chim. Acta, 382, 189 (1999); doi:10.1016/S0003-2670(98)00791-0.
B. Unnikrishnan, P.L. Ru, S.M. Chen and V. Mani, Sens. Actuators B, 177, 887 (2013); doi:10.1016/j.snb.2012.11.102.
S. Yurchenko and U. Mölder, Food Chem., 96, 325 (2006); doi:10.1016/j.foodchem.2005.04.009.
J. Kieber and P.J. Seaton, Anal. Chem., 67, 3261 (1995); doi:10.1021/ac00114a024.
X. Wang, E. Adams and A. Van Schepdael, Talanta, 97, 142 (2012); doi:10.1016/j.talanta.2012.04.008.
L.-F. Cai, Y. Zhu, G.-S. Du and Q. Fang, Anal. Chem., 84, 446 (2012); doi:10.1021/ac2029198.
G.M. Walker, J.Q. Sai, A. Richmond, M. Stremler, C.Y. Chung and J.P. Wikswo, Lab Chip, 5, 611 (2005); doi:10.1039/b417245k.
S. Gotz, T. Revermann and U. Karst, Lab Chip, 7, 93 (2007); doi:10.1039/b609739a.
A. Huebner, L.F. Olguin, D. Bratton, G. Whyte, W.T.S. Huck, A.J. de Mello, J.B. Edel, C. Abell and F. Hollfelder, Anal. Chem., 80, 3890 (2008); doi:10.1021/ac800338z.
Z.J. Jia, Q. Fang and Z.L. Fang, Anal. Chem., 76, 5597 (2004); doi:10.1021/ac0494477.
G.M. Whitesides, E. Ostuni, S. Takayama, X.Y. Jiang and D.E. Ingber, Annu. Rev. Biomed. Eng., 3, 335 (2001); doi:10.1146/annurev.bioeng.3.1.335.
C.G. Khan Malek, Anal. Bioanal. Chem., 385, 1362 (2006); doi:10.1007/s00216-006-0517-z.
A.W. Martinez, S.T. Phillips, M.J. Butte and G.M. Whitesides, Angew. Chem. Int. Ed., 46, 1318 (2007); doi:10.1002/anie.200603817.
K.M. Schilling, A.L. Lepore, J.A. Kurian and A.W. Martinez, Anal. Chem., 84, 1579 (2012); doi:10.1021/ac202837s.
X. Li, J.F. Tian, G. Garnier and W. Shen, Colloids Surf. B, 76, 564 (2010); doi:10.1016/j.colsurfb.2009.12.023.
Y. Lu, W.W. Shi, L. Jiang, J.H. Qin and B.C. Lin, Electrophoresis, 30, 1497 (2009); doi:10.1002/elps.200800563.
L.F. Cai, Y.Y. Wu, C.X. Xu and Z.F. Chen, J. Chem. Educ., 90, 232 (2013); doi:10.1021/ed300385j.
Z. Kang, Food Analysis and Detection, Light Industry Press, Beijing, China (2006).