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A New Anthraquinone from the Fruit of Cassia fistula and Its Cytotoxicity
Corresponding Author(s) : Yanqing Ye
Asian Journal of Chemistry,
Vol. 26 No. 14 (2014): Vol 26 Issue 14
Abstract
A new anthraquinone, fistulaquinone A (1) was isolated from the fruits of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. This new compound 1 was tested for its cytotoxicity and it showed potential cytotoxicity against NB4 and PC3 cell with IC50 values of 6.3 and 5.8 μM.
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- V. Duraipandiyan and S. Ignacimuthu, J. Ethnopharmacol., 112, 590 (2007); doi:10.1016/j.jep.2007.04.008.
- S. Rajan, D.S. Baburaj, M. Sethuraman and S. Parimala, Ethnobotany, 6, 19 (2001).
- J. Ma, L.X. Zhang and Y.H. Guan, Chin. J. Ethnomed. Ethnopharm., 5, 178 (2004).
- K.A. Abo, A.A. Adeyemi and A.O. Sobowale, Afr. J. Med. Med. Sci., 30, 9 (2001).
- S. Aurapa and G. Wandee, Int. J. Biomed. Pharm. Sci., 3, 42 (2009).
- P. Sartorelli, S.P. Andrade, M.S. Melhem, F.O. Prado and A.G. Tempone, Phytother. Res., 21, 644 (2007); doi:10.1002/ptr.2131.
- Y.H. Kuo, P.H. Lee and Y.S. Wein, J. Nat. Prod., 65, 1165 (2002); doi:10.1021/np020003k.
- S.L. Jothy, Z. Zakaria, Y. Chen, Y.L. Lau, L.Y. Latha, L.N. Shin and S. Sasidharan, Molecules, 16, 7583 (2011); doi:10.3390/molecules16097583.
- W. Zhao, X.Y. Zeng, T. Zhang, L. Wang, G.Y. Yang, Y.K. Chen, Q.F. Hu and M.M. Miao, Phytochem. Lett., 6, 179 (2013); doi:10.1016/j.phytol.2012.12.006.
- Y.C. Hu, E.D. Martinez and J.B. MacMillan, J. Nat. Prod., 75, 1759 (2012); doi:10.1021/np3004326.
- P. Tuntiwachwuttikul, P. Phansa, Y. Pootaeng-On and W.C. Taylor, Chem. Pharm. Bull. (Tokyo), 54, 44 (2006); doi:10.1248/cpb.54.44.
- X.M. Gao, R.R. Wang, D.Y. Niu, C.Y. Meng, L.M. Yang, Y.T. Zheng, G.Y. Yang, Q.F. Hu, H.D. Sun and W.L. Xiao, J. Nat. Prod., 76, 1052 (2013); doi:10.1021/np400070x.
References
V. Duraipandiyan and S. Ignacimuthu, J. Ethnopharmacol., 112, 590 (2007); doi:10.1016/j.jep.2007.04.008.
S. Rajan, D.S. Baburaj, M. Sethuraman and S. Parimala, Ethnobotany, 6, 19 (2001).
J. Ma, L.X. Zhang and Y.H. Guan, Chin. J. Ethnomed. Ethnopharm., 5, 178 (2004).
K.A. Abo, A.A. Adeyemi and A.O. Sobowale, Afr. J. Med. Med. Sci., 30, 9 (2001).
S. Aurapa and G. Wandee, Int. J. Biomed. Pharm. Sci., 3, 42 (2009).
P. Sartorelli, S.P. Andrade, M.S. Melhem, F.O. Prado and A.G. Tempone, Phytother. Res., 21, 644 (2007); doi:10.1002/ptr.2131.
Y.H. Kuo, P.H. Lee and Y.S. Wein, J. Nat. Prod., 65, 1165 (2002); doi:10.1021/np020003k.
S.L. Jothy, Z. Zakaria, Y. Chen, Y.L. Lau, L.Y. Latha, L.N. Shin and S. Sasidharan, Molecules, 16, 7583 (2011); doi:10.3390/molecules16097583.
W. Zhao, X.Y. Zeng, T. Zhang, L. Wang, G.Y. Yang, Y.K. Chen, Q.F. Hu and M.M. Miao, Phytochem. Lett., 6, 179 (2013); doi:10.1016/j.phytol.2012.12.006.
Y.C. Hu, E.D. Martinez and J.B. MacMillan, J. Nat. Prod., 75, 1759 (2012); doi:10.1021/np3004326.
P. Tuntiwachwuttikul, P. Phansa, Y. Pootaeng-On and W.C. Taylor, Chem. Pharm. Bull. (Tokyo), 54, 44 (2006); doi:10.1248/cpb.54.44.
X.M. Gao, R.R. Wang, D.Y. Niu, C.Y. Meng, L.M. Yang, Y.T. Zheng, G.Y. Yang, Q.F. Hu, H.D. Sun and W.L. Xiao, J. Nat. Prod., 76, 1052 (2013); doi:10.1021/np400070x.