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Extraction of Paeoniflorin from Radix Paeoniae Alba by Supercritical CO2
Corresponding Author(s) : Jian-Zhong Jin
Asian Journal of Chemistry,
Vol. 26 No. 15 (2014): Vol 26 Issue 15
Abstract
In this study the supercritical CO2 extracting technology was applied to extract paeoniflorin from Radix Paeoniae Alba, single factor experiment was used to study the influence of ethanol concentration, ratio of modifier dosage, extracting pressure, extracting temperature, extracting time and flow rate of CO2 on the extraction yield of paeoniflorin. The optimum extracting parameters were established with ethanol concentration of 95 %, ratio of modifier dosage of 2.5, extracting pressure of 25 MPa, extracting temperature of 50 °C, flow rate of CO2 of 10 kg h-1 and extracting time of 1.5 h. The optimum technology for supercritical CO2 extraction of paeoniflorin from Radix Paeoniae Alba was high efficient, extraction yield 0.99 %.
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- Committee of National Pharmacopoeia, Pharmacopoeia of People's Republic of China, Press of Chemical Industy, Beijing, vol. 1, pp. 178-179 (2000).
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- G.M. Svetlana, D.L. Zika, P.Z. Zoran and S.V. Senka, Hem. Ind., 65, 147 (2011).
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References
Committee of National Pharmacopoeia, Pharmacopoeia of People's Republic of China, Press of Chemical Industy, Beijing, vol. 1, pp. 178-179 (2000).
C. Feng, M. Liu, X.W. Shi, W. Yang, D.Z. Kong, K.F. Duan and Q. Wang, J. Ethnopharmacol., 130, 407 (2010); doi:10.1016/j.jep.2010.05.028.
F. Liu and G.D. Yang, Chin. Trad. Pat. Med., 25, 792 (2003).
Q.F. Wu, Y.L. Yan and X.H. Lou, Chin. Trad. Pat. Med., 28, 1379 (2006).
Q.F. Tao, J. Chin. Med. Mater., 22, 94 (1999).
Q.Y. Lin and S.Q. Wang, J. Chin. Med. Mater., 25, 737 (2002).
G.M. Svetlana, D.L. Zika, P.Z. Zoran and S.V. Senka, Hem. Ind., 65, 147 (2011).
J.A.R. Uribe, J.I.N. Perez, H.C. Kauil, G.R. Rubio and C.G. Alcocer, J. Supercrit. Fluids, 56, 174 (2011); doi:10.1016/j.supflu.2010.12.007.
A. Piras, A. Rosa, D. Falconieri, S. Porcedda, M.A. Dessì and B. Marongiu, Molecules, 14, 2573 (2009); doi:10.3390/molecules14072573.
K.L. Nyam, C.P. Tan, O.M. Lai, K. Long and Y.B. Che Man, Food Bioprocess Technol., 4, 1432 (2011); doi:10.1007/s11947-009-0253-4.
L.H. Wang, Y.T. Song, Y.Y. Cheng and X.S. Liu, J. Sep. Sci., 31, 321 (2008); doi:10.1002/jssc.200700386.