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Vol. 26 No. 16 (2014): Vol 26 Issue 16

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A New Flavone from Flower Buds of Rosa rugosa

https://doi.org/10.14233/ajchem.2014.16283
Ying Qin
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Yuchun Yang
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Congfang Xia
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Yinke Li
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Haiying Yang
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Yanqing Ye
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Qiufen Hu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China
Xue-Mei Gao
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan Province, P.R. China

Corresponding Author(s) : Xue-Mei Gao

gao_xuemei@hotmail.com

Asian Journal of Chemistry, Vol. 26 No. 16 (2014): Vol 26 Issue 16

Abstract

A new flavone, rugosaflavonoid H (1) were isolated from the flower buds of Rosa rugosa. Its structures were determined by spectroscopic methods including 1D and 2D-NMR technique. Compound 1 was also tested for its cytotoxicity against five human tumor cell lines (NB4, A549, SHSY5Y, PC3, and MCF7) and it exhibited cytotoxicity against NB4 and MCF7 cells with IC50 values of 8.2 and 7.6 μM, respectively.

Keywords

Flavone Rosa rugosa Cytotoxicity
Qin, Y., Yang, Y., Xia, C., Li, Y., Yang, H., Ye, Y., … Gao, X.-M. (2014). A New Flavone from Flower Buds of Rosa rugosa. Asian Journal of Chemistry, 26(16), 4982–4984. https://doi.org/10.14233/ajchem.2014.16283
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