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Vol. 26 No. 16 (2014): Vol 26 Issue 16

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Synthesis and Properties of Chitosan-Pectin Microspheres

https://doi.org/10.14233/ajchem.2014.16884
Xuefang Zheng
College of Chemical Engineering, Hebei Normal University of Science and Technology, Qinhuangdao 066600, P.R. China
Qi Lian
College of Chemical Engineering, Hebei Normal University of Science and Technology, Qinhuangdao 066600, P.R. China
Youshun Peng
College of Chemical Engineering, Hebei Normal University of Science and Technology, Qinhuangdao 066600, P.R. China
Sitao Song
College of Chemical Engineering, Hebei Normal University of Science and Technology, Qinhuangdao 066600, P.R. China

Corresponding Author(s) : Qi Lian

xuefang-zheng@163.com

Asian Journal of Chemistry, Vol. 26 No. 16 (2014): Vol 26 Issue 16

Abstract

Chitosan-pectin (CS-PT) microspheres were prepared by inverse phase suspension method, with liquid paraffin and Span 80 as the oil phase, chitosan-pectin acetic acid as aqueous solution, glutaraldehyde as cross-linker. Based on the theory of inverse emulsion polymerization, the optimal conditions were studied by single-factor test: the reaction temperature was 60 °C, chitosan-pectin solution of acetic acid was 0.025 g/mL, mCS:mPT = 4:1, the oil were liquid paraffin and a mixture of Span 80, the volume ratio of oil phase to aqueous was 2:1, the dosage of cross-linker was 0.30 mL, the dosage of Span 80 was 0.6 g, the time of reacting was 3 h. The synthesized chitosan-pectin microspheres are dark yellow and have smoother appearance and the diameter is about 50 microns. The structure of microspheres were characterized by FT-IR, Bio-optical microscope and X-ray diffraction studies. The adsorption of chitosan-pectin microspheres was good in the solution of methylene blue.

Keywords

Chitosan Pectin Microspheres Methylene blue
Zheng, X., Lian, Q., Peng, Y., & Song, S. (2014). Synthesis and Properties of Chitosan-Pectin Microspheres. Asian Journal of Chemistry, 26(16), 5230–5234. https://doi.org/10.14233/ajchem.2014.16884
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References
  1. R.A.A. Muzzarelli, Carbohydr. Polym., 29, 309 (1996); doi:10.1016/S0144-8617(96)00033-1.
  2. R.A.A. Muzzarelli, Natural Chelating Polymers, Pergamon Press Ltd, Oxford (1973).
  3. H.I. Bolker, Natural and Synthetic Polymer: An Introduction, Marcel Dekker Inc, New York (1974).
  4. J.D. Dee, O. Rhode and R. Wachter, Cosmetics and Toiletries, 116, 39 (2001).
  5. A.K. Singla and M.J. Chawla, Pharm. Pharmacol., 53, 1047 (2001); doi:10.1211/0022357011776441.
  6. H.K. No and S.P.J. Meyers, Agric. Food Chem., 37, 580 (1989); doi:10.1021/jf00087a002.
  7. K. Kurita, Polym. Degrad. Stab., 59, 117 (1998); doi:10.1016/S0141-3910(97)00160-2.
  8. S.E. Bailey, T.J. Olin, R.M. Bricka and D.D. Adrian, Water Res., 33, 2469 (1999); doi:10.1016/S0043-1354(98)00475-8.
  9. Y. Sawayanagi, N. Nambu and T. Nagai, Chem. Pharm. Bull. (Tokyo), 31, 2064 (1983); doi:10.1248/cpb.31.2064.
  10. T.C. Yang and R.R. Zall, Ind. Eng. Chem. Prod. Res. Dev., 23, 168 (1984); doi:10.1021/i300013a033.
  11. J.-K. Yang, I.-L. Shih, Y.-M. Tzeng and S.-L. Wang, Enzyme Microb. Technol., 26, 406 (2000); doi:10.1016/S0141-0229(99)00164-7.
  12. T.A. Khan, K.K. Peh and H.S. Ch’ng, J. Pharm. Pharm. Sci., 5, 205 (2002).
  13. A. Grenha, C.I. Grainger, L.A. Dailey, B. Seijo, G.P. Martin, C. Remuñán-López and B. Forbes, Eur. J. Pharm. Sci., 31, 73 (2007); doi:10.1016/j.ejps.2007.02.008.
  14. D.H. Li, L.M. Liu, K.L. Tian, J. Liu and X. Fan, Carbohydr. Polym., 67, 40 (2007); doi:10.1016/j.carbpol.2006.04.022.
  15. M. Turkoglu and T. Ugurlu, Eur. J. Pharm. Biopharm., 53, 65 (2002); doi:10.1016/S0939-6411(01)00225-9.
  16. O. Pillai and R. Panchagnula, Curr. Opin. Chem. Biol., 5, 447 (2001); doi:10.1016/S1367-5931(00)00227-1.
  17. E. Khor and L.Y. Lim, Biomaterials, 24, 2339 (2003); doi:10.1016/S0142-9612(03)00026-7.
  18. S. Xin-Yuan, Bioact. Compat. Polym., 19, 467 (2004); doi:10.1177/0883911504048410.
  19. G. Crini, Bioresour. Technol., 97, 1061 (2006); doi:10.1016/j.biortech.2005.05.001.
  20. D.N. Venkatesh, A.K. Reddy, M.K. Samanta and B. Suresh, Asian J. Pharm., 3, 50 (2009).
  21. T. Katav, L.S. Liu, T. Traitel, R. Goldbart, M. Wolfson and J. Kost, J. Control. Rel., 130, 183 (2008); doi:10.1016/j.jconrel.2008.06.002.
  22. O. Chambin, G. Dupuis, D. Champion, A. Voilley and Y. Pourcelot, Int. J. Pharm., 321, 86 (2006); doi:10.1016/j.ijpharm.2006.05.015.
  23. V.R. Sinha and R. Kumria, Int. J. Pharm., 224, 19 (2001); doi:10.1016/S0378-5173(01)00720-7.
  24. M.R. Nazar, M. Jahanzeb and Z.S. Zuhair, Iran Polym. J., 20, 147 (2011).
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