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Synthesis and Antibacterial Activity of Dihydromyricetin-Co(II)
Corresponding Author(s) : Hai-Xia Li
Asian Journal of Chemistry,
Vol. 26 No. 19 (2014): Vol 26 Issue 19
Abstract
Dihydromyricetin is a natural food additives with good prospects in food industry, But its little research is on dihydromyricetin complex with better effects. Antibacterial agent is very important in food industry, but little attention has been devoted to the relationship between dihydromyricetin-metal complex and antibacterial activity. In this paper, dihydromyricetin-Co(II) has been prepared and the interaction of dihydromyricetin-Co(II) complx with antibacterial activity was investigated by tube double dilution method. The results indicate that the dihydromyricetin-Co(II) conditional stability constant is 6.47 × 1013 L2 mol-2 and its antibacterial activity could effectively inhibit the growth of Candida albicans. The minimum antimicrobial dosage of dihydromyricetin-Co(II) against Candida albicans was 12.5-25 μg/mL. The minimum bactericidal dosage was 25-50 μg/mL. The result showed dihydromyricetin-Co(II) against Candida albicans was stronger than that of dihydromyricetin.
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- L. Testai, A. Martelli, M. Cristofaro, M.C. Breschi and V. Calderone, J. Pharm. Pharmacol., 65, 750 (2013); doi:10.1111/jphp.12032.
- Y. Sivasothy, S.F. Sulaiman, K.L. Ooi, H. Ibrahim and K. Awang, Food Contr., 30, 714 (2013); doi:10.1016/j.foodcont.2012.09.012.
- Y.A. Kim, Y.S. Tarahovsky, E.A. Yagolnik, S.M. Kuznetsova and E.N. Muzafarov, Biochem. Biophys. Res. Commun., 431, 680 (2013); doi:10.1016/j.bbrc.2013.01.060.
- A. Ali, N. Abdullah, M.J. Maah and I.M. Mustafa, Asian J. Chem., 24, 5063 (2012).
- B. Liu, J. Du, J. Zeng, C. Chen and S. Niu, Eur. Food Res. Technol., 230, 325 (2009); doi:10.1007/s00217-009-1175-0.
- Q. Guo, J. Yuan, J. Zeng, X. He and D. Li, J. Mol. Struct., 1027, 64 (2012); doi:10.1016/j.molstruc.2012.05.063.
- H.X. Li, L.Z. Chen, R.R. Zhai and L. Yang, J. Hainan Med. Univ., 17, 445 (2011).
- J.-N. Li, Synth. React. Inorg. Met.-Org. Nano-Met. Chem., 43, 826 (2013); doi:10.1080/15533174.2012.750343.
- A.A. Jamali, A. Tavakoli and J. Ezzati Nazhad Dolatabadi, Eur. Food Res. Technol., 235, 367 (2012); doi:10.1007/s00217-012-1778-8.
- N. Xiang, R. Zhao and W. Zhong, Cancer Chemother. Pharmacol., 63, 351 (2009); doi:10.1007/s00280-008-0745-3.
- L. Hongli, L. Hongjun and S. Xingming, J. Luohe Vocational Technol. College, 3, 16 (2004).
- E.W. Koneman, S.D. Allen, V.R. Dowell Jr. and H.M. Sommers, Color Atlas and Textbook of Diagnostic Microbiology, J.B. Lippincott Co., USA, pp. 321 (1979).
- National Committee for Clinical Laboratory Standards, Methods for Determining Bactericidal Activity of Antimicrobial Agents, Approved Guideline M26-A, National Committee for Clinical Laboratory Standards, Wayne (1999).
- Y. Hirakata, H. Yano, K. Arai, M. Kitagawa, M. Hatta, H. Kunishima and M. Kaku, J. Infect. Chemother., 18, 347 (2012); doi:10.1007/s10156-011-0342-y.
- B.G. Tweedy, Phytopathology, 55, 910 (1964).
- F. Ahmadi, M. Saberkari, R. Abiri, H.M. Motlagh and H. Saberkari, Appl. Biochem. Biotechnol., 170, 988 (2013); doi:10.1007/s12010-013-0255-6.
- Y.-J. Wang, R.-D. Hu, D.-H. Jiang, P.-H. Zhang, Q.-Y. Lin and Y.-Y. Wang, J. Fluoresc., 21, 813 (2011); doi:10.1007/s10895-010-0775-1.
- R.S. Azarudeen and A.R. Burkanudeen, J. Inorg. Organomet. Polym. Mater., 22, 791 (2012); doi:10.1007/s10904-011-9631-2.
References
L. Testai, A. Martelli, M. Cristofaro, M.C. Breschi and V. Calderone, J. Pharm. Pharmacol., 65, 750 (2013); doi:10.1111/jphp.12032.
Y. Sivasothy, S.F. Sulaiman, K.L. Ooi, H. Ibrahim and K. Awang, Food Contr., 30, 714 (2013); doi:10.1016/j.foodcont.2012.09.012.
Y.A. Kim, Y.S. Tarahovsky, E.A. Yagolnik, S.M. Kuznetsova and E.N. Muzafarov, Biochem. Biophys. Res. Commun., 431, 680 (2013); doi:10.1016/j.bbrc.2013.01.060.
A. Ali, N. Abdullah, M.J. Maah and I.M. Mustafa, Asian J. Chem., 24, 5063 (2012).
B. Liu, J. Du, J. Zeng, C. Chen and S. Niu, Eur. Food Res. Technol., 230, 325 (2009); doi:10.1007/s00217-009-1175-0.
Q. Guo, J. Yuan, J. Zeng, X. He and D. Li, J. Mol. Struct., 1027, 64 (2012); doi:10.1016/j.molstruc.2012.05.063.
H.X. Li, L.Z. Chen, R.R. Zhai and L. Yang, J. Hainan Med. Univ., 17, 445 (2011).
J.-N. Li, Synth. React. Inorg. Met.-Org. Nano-Met. Chem., 43, 826 (2013); doi:10.1080/15533174.2012.750343.
A.A. Jamali, A. Tavakoli and J. Ezzati Nazhad Dolatabadi, Eur. Food Res. Technol., 235, 367 (2012); doi:10.1007/s00217-012-1778-8.
N. Xiang, R. Zhao and W. Zhong, Cancer Chemother. Pharmacol., 63, 351 (2009); doi:10.1007/s00280-008-0745-3.
L. Hongli, L. Hongjun and S. Xingming, J. Luohe Vocational Technol. College, 3, 16 (2004).
E.W. Koneman, S.D. Allen, V.R. Dowell Jr. and H.M. Sommers, Color Atlas and Textbook of Diagnostic Microbiology, J.B. Lippincott Co., USA, pp. 321 (1979).
National Committee for Clinical Laboratory Standards, Methods for Determining Bactericidal Activity of Antimicrobial Agents, Approved Guideline M26-A, National Committee for Clinical Laboratory Standards, Wayne (1999).
Y. Hirakata, H. Yano, K. Arai, M. Kitagawa, M. Hatta, H. Kunishima and M. Kaku, J. Infect. Chemother., 18, 347 (2012); doi:10.1007/s10156-011-0342-y.
B.G. Tweedy, Phytopathology, 55, 910 (1964).
F. Ahmadi, M. Saberkari, R. Abiri, H.M. Motlagh and H. Saberkari, Appl. Biochem. Biotechnol., 170, 988 (2013); doi:10.1007/s12010-013-0255-6.
Y.-J. Wang, R.-D. Hu, D.-H. Jiang, P.-H. Zhang, Q.-Y. Lin and Y.-Y. Wang, J. Fluoresc., 21, 813 (2011); doi:10.1007/s10895-010-0775-1.
R.S. Azarudeen and A.R. Burkanudeen, J. Inorg. Organomet. Polym. Mater., 22, 791 (2012); doi:10.1007/s10904-011-9631-2.