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Vol. 38 No. 10 (2026): Vol 38, Issue 10, 2026

Copyright (c) 2026 Modeste TRAORE, Samson GUENNE, Arthur A.A. DABONE, Ghislain KOBENDE, Mamounata DIAO, Hemayoro SAMA, Juste Y. BONZI , Basile TINDANO, Moussa COMPAORE, Gérard COULIBALY, Adama HILOU, Martin. KIENDREBEOGO

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Phytochemical Profile, Adaptogenic and Neuroprotective Properties of Annona senegalensis Pers. (Annonaceae): A Medicinal Plant from Bankui Region of Burkina Faso

https://doi.org/10.14233/ajchem.2026.36668
Modeste Traoré
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0002-0136-977X
Samson Guenne
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso; Laboratory of Biochemistry, Biotechnology, Food Technology and Nutrition (LABIOTAN), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0001-5405-0861
Arthur A.A. Dabone
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0009-0003-7709-8763
Ghislain T. Kobende
Laboratory of Biochemistry, Biotechnology, Food Technology and Nutrition (LABIOTAN), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0009-0000-6843-1833
Mamounata Diao
Laboratory of Biochemistry, Biotechnology, Food Technology and Nutrition (LABIOTAN), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0002-9383-8165
Hemayoro Sama
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso; Laboratory of Biochemistry, Biotechnology, Food Technology and Nutrition (LABIOTAN), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0002-7028-4032
Juste Y. Bonzi
Laboratory of Non-Communicable Diseases, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0001-8430-0761
Basile Tindano
Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0009-0005-4906-6574
Moussa Compaore
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0002-0898-4556
Gérard Coulibaly
Laboratory of Non-Communicable Diseases, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0002-9406-1319
Adama Hilou
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0009-0007-5686-0834
Martin Kiendrebeogo
Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso
https://orcid.org/0000-0003-2335-6184

Corresponding Author(s) : Modeste Traoré

modeste_traore@ujkz.bf

Asian Journal of Chemistry, Vol. 38 No. 10 (2026): Vol 38, Issue 10, 2026

Abstract

This study aimed to evaluate the qualitative phytochemical profile of the hydroethanolic extract of Annona senegalensis leaves and to validate its biological properties. High-performance thin-layer chromatography (HPTLC) analysis, quantification of phytochemical compounds, followed by in vivo evaluation of antioxidant, analgesic and neuroprotective activities were performed using standardized methods. HPTLC analysis revealed a rich profile of phenolic and terpenic compounds, with rutin and quercitrin identified as prominent constituents and further confirmed by spectrophotometric quantification. The confirmed phytochemical profile is closely correlated with in vitro antioxidant properties (IC50 of 27.81 ± 2.35 µg/mL) and significant inhibition of lipid peroxidation (70.84 ± 2.06%). The extract was well tolerated and showed anxiolytic and analgesic effects without producing sedation. The phenolic and terpenic constituents of the extract may contribute to its biological effects and to the ergogenic responses and metabolic adaptations observed under physical stress. These findings provide scientific support for the traditional use of Annona senegalensis Pers. in African medicine.

Keywords

Annona senegalensis Pers. HPTLC Adaptogen Neuroprotection
(1)
Traoré, M.; Guenne, S.; Dabone, A. A.; Kobende, G. T.; Diao, M.; Sama, H.; Bonzi, J. Y.; Tindano, B.; Compaore, M.; Coulibaly, G. Phytochemical Profile, Adaptogenic and Neuroprotective Properties of Annona Senegalensis Pers. (Annonaceae): A Medicinal Plant from Bankui Region of Burkina Faso. ajc 2026, 38, 2735-2742.
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Author Biographies

Samson Guenne, Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso; Laboratory of Biochemistry, Biotechnology, Food Technology and Nutrition (LABIOTAN), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso

PHD, Department of Biochemistry and Microbiology

Arthur A.A. Dabone, Laboratory of Biochemistry and Applied Chemistry (LABIOCA), Department of Biochemistry and Microbiology, Université Joseph KI-ZERBO, Ouagadougou BP 7021, Burkina Faso

Department of Biochemistry and Microbiology

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