Synthesis, Spectroscopic and Biological Activities of Aromatic Schiff Base

Manawwer Alam; Naser M. Alandis; Mohammed Rafi Shaik; Shahanavaj Khan; Suliman Y. Alomar

doi:10.14233/ajchem.2014.17036

Issue

Vol. 26 No. 21 (2014): Vol 26 Issue 21

Issue Published : September 30, 2014

This work is licensed under a Creative Commons Attribution 4.0 International License.

Synthesis, Spectroscopic and Biological Activities of Aromatic Schiff Base

https://doi.org/10.14233/ajchem.2014.17036

Manawwer Alam

Research Center-College of Science, King Saud University, P.O. Box. 2455, Riyadh 11451, Kingdom of Saudi Arabia

Naser M. Alandis

Department of Chemistry, College of Science, King Saud University, P.O. Box. 2455, Riyadh 11451, Kingdom of Saudi Arabia

Mohammed Rafi Shaik

Department of Chemistry, College of Science, King Saud University, P.O. Box. 2455, Riyadh 11451, Kingdom of Saudi Arabia

Shahanavaj Khan

Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box. 2457, Riyadh 11451, Kingdom of Saudi Arabia

Suliman Y. Alomar

Department of Zoology, College of Science, King Saud University, P.O. Box, 2455, Riyadh 11451, Kingdom of Saudi Arabia

Corresponding Author(s) : Manawwer Alam

malamiitd@gmail.com

Asian Journal of Chemistry, Vol. 26 No. 21 (2014): Vol 26 Issue 21
Article Published : October 1, 2014

Abstract

In this paper the preparation of 5-[(2-aminophenyl)imino]-3,3-dimethylcyclohexanone and 5-[(4-aminophenyl)imino]-3,3-dimethyl cyclohexanone in the ethanolic medium. The structures of these compounds were characterized by elemental analysis, FT-IR, ¹H-NMR and ¹³C-NMR. The antibacterial and antifungal activity of these compounds has been investigated by agar disc diffusion method using Gram-negative and Gram-positive bacterial strain and four kinds of fungi.

Keywords

Schiff base Dimedone o-Phenylenediamine p-Phenylenediamine

Alam, M., M. Alandis, N., Rafi Shaik, M., Khan, S., & Y. Alomar, S. (2014). Synthesis, Spectroscopic and Biological Activities of Aromatic Schiff Base. Asian Journal of Chemistry, 26(21), 7377–7380. https://doi.org/10.14233/ajchem.2014.17036

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References

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References

B.C. Sekhar, J. Heterocycl. Chem., 41, 807 (2004); doi:10.1002/jhet.5570410601.

M. Asadi, S. Torabi and K. Mohammadi, Spectrochim. Acta A, 122, 676 (2014); doi:10.1016/j.saa.2013.09.098.

A.A. Abou-Hussein and W. Linert, Spectrochim. Acta A, 117, 763 (2014); doi:10.1016/j.saa.2013.06.078.

O.I.E.- Sabbagh, M.A. Shabaan, H.H. Kadry and E.S. Al-Din, Arch. Pharm. Chem. Life Sci., 9, 519 (2010); doi:10.1002/ardp.200900296.

B.A. Saeed and I.B. Musad, Molecules, 14, 2278 (2009); doi:10.3390/molecules14062278.

M. Ghandi, T. Momeni, M.T. Nazeri, N. Zarezadeh and M. Kubicki, Tetrahedron Lett., 54, 2983 (2013); doi:10.1016/j.tetlet.2013.03.131.

D.P. Singh, V. Grover, P. Rathi, K. Jain, Arabian J. Chem., doi:10.1016/j.arabjc.2013.07.004.

D.-Q. Shi, S.-N. Ni, J.-W. Fang-Yang, J.-W. Shi, G.-L. Dou, X.-Y. Li and X.-S. Wang, J. Heterocycl. Chem., 45, 653 (2008); doi:10.1002/jhet.5570450303.

L. Fotouhi, M.M. Heravi, A. Fatehi and K. Bakhtiari, Tetrahedron Lett., 48, 5379 (2007); doi:10.1016/j.tetlet.2007.06.035.

S. Khaksar, A. Rouhollahpour and S.M. Talesh, J. Fluor. Chem., 141, 11 (2012); doi:10.1016/j.jfluchem.2012.05.014.

S. Kumar, P. Sharma, K.K. Kapoor and M.S. Hundal, Tetrahedron, 64, 536 (2008); doi:10.1016/j.tet.2007.11.008.

J. Quiroga, P.A. Acosta, S. Cruz, R. Abonia, B. Insuasty, M. Nogueras and J. Cobo, Tetrahedron Lett., 51, 5443 (2010); doi:10.1016/j.tetlet.2010.08.021.

J. Safari, S.H. Banitaba and S. Dehghan Khalili, Chin. J. Catal., 32, 1850 (2011); doi:10.1016/S1872-2067(10)60295-1.

S. Khaksar and N. Behzadi, Chin. J. Catal., 33, 982 (2012); doi:10.1016/S1872-2067(11)60393-8.

P. Sivaguru and A. Lalitha, Chin. Chem. Lett., 25, 321 (2014); doi:10.1016/j.cclet.2013.11.043.

S. Abdolmohammadi, Chin. Chem. Lett., 24, 318 (2013); doi:10.1016/j.cclet.2013.02.017.

E.S.E. Ashry, L.F. Awad, E.S.I. Ibrahim and O.K. Bdewy, ARKIVOC, 178 (2005); doi:10.3998/ark.5550190.0007.220.

N.G. Kozlov and A.P. Kadutskii, Tetrahedron Lett., 49, 4560 (2008); doi:10.1016/j.tetlet.2008.04.160.

CLSI, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically Approved Standard; CLSI document M07-A8; CLSI: Wayne, PA, USA (2009).

CLSI, Performance Standard for Antimicrobial Susceptibility Testing; Twenty-First Information Supplement; CLSI document M100-S21; CLSI: Wayne, PA, USA (2011).

Issue

Vol. 26 No. 21 (2014): Vol 26 Issue 21

Synthesis, Spectroscopic and Biological Activities of Aromatic Schiff Base

Corresponding Author(s) : Manawwer Alam

Abstract

Keywords

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