Microwave Assisted Synthesis of Barium Titanate Nanoparticles and Its Effects on the Proliferation of Primary Osteoblasts in vitro

Wenying Wang; Baofeng Zheng; Yanyan Ma; Zhu Liu; Zhilin Li; Guoqiang Zhou

doi:10.14233/ajchem.2014.17155

Issue

Vol. 26 No. 21 (2014): Vol 26 Issue 21

Issue Published : September 30, 2014

This work is licensed under a Creative Commons Attribution 4.0 International License.

Microwave Assisted Synthesis of Barium Titanate Nanoparticles and Its Effects on the Proliferation of Primary Osteoblasts in vitro

https://doi.org/10.14233/ajchem.2014.17155

Wenying Wang

College of Chemistry and Environmental Science, Hebei University, Baoding, P.R. China

Baofeng Zheng

College of Chemistry and Environmental Science, Hebei University, Baoding, P.R. China

Yanyan Ma

College of Chemistry and Environmental Science, Hebei University, Baoding, P.R. China

Zhu Liu

College of Chemistry and Environmental Science, Hebei University, Baoding, P.R. China

Zhilin Li

College of Chemistry and Environmental Science, Hebei University, Baoding, P.R. China

Guoqiang Zhou

College of Chemistry and Environmental Science, Hebei University, Baoding, P.R. China ; Key Laboratory of Chemical Biology of Hebei Province, Hebei University, Baoding, P.R. China

Corresponding Author(s) : Zhilin Li

zhougq1982@163.com

Asian Journal of Chemistry, Vol. 26 No. 21 (2014): Vol 26 Issue 21
Article Published : October 1, 2014

Abstract

The barium titanate nanoparticles were successfully synthesized using microwave synthesis method and evaluated for antiproliferation activity against primary osteoblasts. The effects of microwave irradiation power and reaction time on the reaction rate and size control of barium titanate nanoparticles were investigated. The data revealed that the nanoparticle size decreasesd with increasing irradiation power. The barium titanate nanoparticles were formed after 20 min of microwave irradiation. The barium titanate nanoparticles synthesized were analyzed by field emission scanning electron microscopy, powder X-ray diffraction, Fourier transform infrared spectroscopy and dynamic light scattering. The barium titanate nanoparticles were nearly spherical particles with an average size of 80-100 nm. The antiproliferation activity of barium titanate nanoparticles showed that the inhibition effects followed dose and time dependent manner. The inhibition effects were increased with decreasing size and the effects may be related to cell apoptosis mechanism.

Keywords

Barium Titanate Nanoparticles Microwave Synthesis Osteoblasts

Wang, W., Zheng, B., Ma, Y., Liu, Z., Li, Z., & Zhou, G. (2014). Microwave Assisted Synthesis of Barium Titanate Nanoparticles and Its Effects on the Proliferation of Primary Osteoblasts in vitro. Asian Journal of Chemistry, 26(21), 7419–7423. https://doi.org/10.14233/ajchem.2014.17155

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W.J. Merz, Phys. Rev., 76, 1221 (1949); doi:10.1103/PhysRev.76.1221.

A.I. Kingon, S.K. Streiffer, C. Basceri and S.R. Summerfelt, MRS Bull., 21, 46 (1996).

Y. Luo and X. Liu, Mater. Lett., 59, 3881 (2005); doi:10.1016/j.matlet.2005.06.065.

M. Mori, T. Kineri, K. Kadono, T. Sakaguchi, M. Miya, H. Wakabayashi and T. Tsuchiya, J. Am. Ceram. Soc., 78, 2391 (1995); doi:10.1111/j.1151-2916.1995.tb08674.x.

P.K. Singh, S. Cochrane, W.T. Liu, K. Chen, D.B. Knorr, J.M. Borrego, E.J. Rymaszewski and T.M. Lu, Appl. Phys. Lett., 66, 3683 (1995); doi:10.1063/1.114140.

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Issue

Vol. 26 No. 21 (2014): Vol 26 Issue 21

Microwave Assisted Synthesis of Barium Titanate Nanoparticles and Its Effects on the Proliferation of Primary Osteoblasts in vitro

Corresponding Author(s) : Zhilin Li

Abstract

Keywords

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