Copyright (c) 2025 LITHA T T, Dr. PRASEETHA P NAIR
This work is licensed under a Creative Commons Attribution 4.0 International License.
Investigation on the Potentials of Nanocomposites Derived from Polylactic Acid-Polycaprolactone Blends using different Nanofillers as Biomedical Implants
Corresponding Author(s) : T.T. Litha
Asian Journal of Chemistry,
Vol. 37 No. 2 (2025): Vol 37 Issue 2, 2025
Abstract
In present work, an attempt is made to synthesize polymer bio-nanocomposites suitable for biomedical implants based on polylactic acid-polycaprolactone (PLA/PCL) blend reinforced with different nanofillers. The inorganic filler, montmorillonite nanoclay (MMT), whereas graphene oxide (GO) and reduced graphene oxide (rGO) served as carbon-based nanofillers within the composite. Blends of polylactic acid (PLA) and polyvinyl chloride (PCL) were reinforced with hydroxyapatite in order to generate superior materials. The tensile strength and Young’s modulus of PLA-PCL blend nanocomposites show an increase of about 117% and 53%, respectively, when compared to pure PLA, whereas the elongation at break observes a decrease of 38%.
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- J. Nandhini, E. Karthikeyan and S. Rajeshkumar, Discov. Nano, 19, 86 (2024); https://doi.org/10.1186/s11671-024-04007-7
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References
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H. Liu, R. Jian, H. Chen, X. Tian, C. Sun, J. Zhu, Z. Yang, J. Sun and C. Wang, Nanomaterials, 9, 950 (2019); https://doi.org/10.3390/nano9070950
N.D. Bikiaris, I. Koumentakou, C. Samiotaki, D. Meimaroglou, A. Karatza, D. Varytimidou, Z. Kalantzis, M. Roussou, R.D. Bikiaris and G.Z. Papageorgiou, Polymers, 15, 1196 (2023); https://doi.org/10.3390/polym15051196
S. Farah, D.G. Anderson and R. Langer, Adv. Drug Deliv. Rev., 107, 367 (2016); https://doi.org/10.1016/j.addr.2016.06.012
V. Rahimkhoei, M. Padervand, M. Hedayat, F. Seidi, E.A. Dawi and A. Akbari, Int. J. Biol. Macromol., 253(Part 1), 126642 (2023); https://doi.org/10.1016/j.ijbiomac.2023.126642
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T.C. Mokhena, M.B. Chabalala, S. Mapukata, A. Mtibe, L. Hlekelele, Z. Cele, M.J. Mochane, B. Ntsendwana, T.A. Nhlapo, T.P. Mokoena, M.F. Bambo, K.P. Matabola, S.S. Ray, E.R. Sadiku and K. Shingange, Macromol. Mater. Eng., 309, 2300388 (2024); https://doi.org/10.1002/mame.202300388
M. Bustamante-Torres, D. Romero-Fierro, B. Arcentales-Vera, S. Pardo and E. Bucio, Polymers, 13, 2998 (2021); https://doi.org/10.3390/polym13172998
A. Vashist, A. Kaushik, A. Ghosal, J. Bala, R. Nikkhah-Moshaie, W.A. Wani, P. Manickam and M. Nair, Gels, 4, 75 (2018); https://doi.org/10.3390/gels4030075
V. Kumar and X. Tang, Polymers, 15, 4259 (2023); https://doi.org/10.3390/polym15214259
K.J. Shah, A.D. Shukla, D.O. Shah and T. Imae, Polymer, 97, 525 (2016); https://doi.org/10.1016/j.polymer.2016.05.066
C.-H. Kim, S.-Y. Lee, K.Y. Rhee and S.-J. Park, Adv. Compos. Hybrid Mater., 7, 55 (2024); https://doi.org/10.1007/s42114-024-00846-1
A.M. Pinto, J. Cabral, D A P. Tanaka, A.M. Mendes and F.D. Magalhães, Polym. Int., 62, 33 (2012); https://doi.org/10.1002/pi.4290
M.I. Sujan, S.D. Sarkar, C.K. Roy, M. Ferdous, A. Goswami, M.A. Gafur and M.S. Azam, J. Polym. Sci., 59, 1043 (2021); https://doi.org/10.1002/pol.20210029
M. Silva, I.S. Pinho, J.A. Covas, N.M. Alves and M.C. Paiva, Funct. Comp. Mater., 2, 8 (2021); https://doi.org/10.1186/s42252-021-00020-6
I. Fortelny, A. Ujcic, L. Fambri and M. Slof, Front. Mater., 6, 206 (2019); https://doi.org/10.3389/fmats.2019.00206
K.P. Sanosh, M.-C. Chu, A. Balakrishnan, T.N. Kim and S.-J. Cho, Bull. Mater. Sci., 32, 465 (2009); https://doi.org/10.1007/s12034-009-0069-x
I. Ielo, G. Calabrese, G. De Luca and S. Conoci, Int. J. Mol. Sci., 23, 9721 (2022); https://doi.org/10.3390/ijms23179721
A.T. Smith, A.M. LaChance, S. Zeng, B. Liu and L. Sun, Mater. Sci., 1, 31 (2019); https://doi.org/10.1016/j.nanoms.2019.02.004
H. Belaid, S. Nagarajan, C. Teyssier, C. Barou, J. Barés, S. Balme, H. Garay, V. Huon, D. Cornu, V. Cavaillès and M. Bechelany, Mater. Sci. Eng. C, 110, 110595 (2020); https://doi.org/10.1016/j.msec.2019.110595
J. Sanes, C. Sánchez, R. Pamies, M.-D. Avilés and M.-D. Bermúdez, Materials, 13, 549 (2020); https://doi.org/10.3390/ma13030549
J.-W. Rhim, S.-I. Hong and C.-S. Ha, LWT-Food Sci. Technol., 42, 612 (2009); https://doi.org/10.1016/j.lwt.2008.02.015
M. Gong, Q. Zhao, L. Dai, Y. Li and T. Jiang, J. Asian Ceram. Soc., 5, 160 (2017); https://doi.org/10.1016/j.jascer.2017.04.001
Y. Shen, T. Jing, W. Ren, J. Zhang, Z.-G. Jiang, Z.-Z. Yu and A. Dasari, Compos. Sci. Technol., 72, 1430 (2012); https://doi.org/10.1016/j.compscitech.2012.05.018
I. Castilla-Cortázar, A. Vidaurre, B. Marí andA.J. Campillo-Fernández, Polymers, 11, 1099 (2019); https://doi.org/10.3390/polym11071099
S. Hassanajili, A. Kaami-Pour, A. Oryan and T. Talaei-Khozani, Mater. Sci. Eng. C Mater. Biol. Appl., 104, 109960 (2019); https://doi.org/10.1016/j.msec.2019.109960
M. Li, P. Xiong, F. Yan, S. Li, C. Ren, Z. Yin, A. Li, H. Li, X. Ji, Y. Zheng and Y. Cheng, Bioactive Mater., 3, 1 (2018); https://doi.org/10.1016/j.bioactmat.2018.01.001