Copyright (c) 2025 Tapashi Ghosh Roy Tapashi
This work is licensed under a Creative Commons Attribution 4.0 International License.
Studies on Vanadate(V) Complexes of an N-Pendent Cyanoethyl Derivative of Octamethyl-Tetraaza Macrocyclic Chelator
Corresponding Author(s) : Tapashi Ghosh Roy
Asian Journal of Chemistry,
Vol. 37 No. 11 (2025): Vol 37 Issue 11, 2025
Abstract
Dihydroperchlorate salt of a 14-membered tetraazamacrocycle, Me8[14]diene·2HClO4 (L·2HClO4) was synthesized by the condensation of 1,2-diaminopropane with acetone in the presence of a stoichiometric amount of perchloric acid. LB, one of the three isomers (LA, LB and LC: isolated from the reduced product of the ligand salt (L·2HClO4), on reflux with excess amount of acrylonitrile produced corresponding white solid product, LBX (trans-N4,N11-bis(2-cyanoethyl) 2,9-C-meso-3,5,7,7,10,12,14,14-tetraazacyclotetradecane). The reactions of LBX with vanadyl acetylacetonate followed by addition of few drops of vinyl cyanide yielded the pale green product, [VO(LBX)(acac)](ClO4)2. The axial substitution reactions on [VO(LBX)(acac)](ClO4)2 with NCS–, NO3–, NO2–, Cl–, Br– and I– furnished different coloured axial substitution products with different geometries. The structural features of the complexes were confirmed using IR, NMR and UV-Vis spectroscopy, revealing their octahedral geometry. Antibacterial studies showed selective activities against Gram-positive and Gram-negative bacteria, suggesting potential biomedical applications.
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- T. Aiyelabola, J. Jordaan, D. Otto and E. Akinkunmi, Adv. Bio. Chem., 11, 79 (2021); https://doi.org/10.4236/abc.2021.113007
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- A. Sabatini and I. Bertini, Inorg. Chem., 4, 959 (1965); https://doi.org/10.1021/ic50029a007
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References
T. Aiyelabola, J. Jordaan, D. Otto and E. Akinkunmi, Adv. Bio. Chem., 11, 79 (2021); https://doi.org/10.4236/abc.2021.113007
Subhash, A. Chaudhary and Mamta, Chem. Pap., 77, 5059 (2023); https://doi.org/10.1007/s11696-023-02843-y
M. Tosun, A. Uysal, A.N. Kursunlu and E Guler, Tetrahedron, 151, 133812 (2024); https://doi.org/10.1016/j.tet.2023.133812
Subhash, A. Chaudhary and Jyoti, J. Chem. Sci., 134, 113 (2022); https://doi.org/10.1007/s12039-022-02109-2
F. Liu and X. Min, Tetrahedron Lett., 169, 155760 (2025); https://doi.org/10.1016/j.tetlet.2025.155760
M. Sutradhar, L.M.D.R.S. Martins, M.F.C. Guedes da Silva and A.J.L. Pombeiro, Coord. Chem. Rev., 301-302, 200 (2015); https://doi.org/10.1016/j.ccr.2015.01.020
R.R. Langeslay, D.M. Kaphan, C.L. Marshall, P.C. Stair, A.P. Sattelberger and M. Delferro, Chem. Rev., 119, 2128 (2019); https://doi.org/10.1021/acs.chemrev.8b00245
S.G. Shankarwar, B.B. Nagolkar, V.A. Shelke and T.K. Chondhekar, Spectrochim. Acta A Mol. Biomol. Spectrosc., 145, 188 (2015); https://doi.org/10.1016/j.saa.2015.02.006
N. Fahmi, M. Upadhyay, N. Sharma and S. Belwal, J. Chem. Res., 44, 336 (2020); https://doi.org/10.1177/1747519819893885
K.R. Chaudhari, A. Kunwar, N. Bhuvanesh and S. Dey, New J. Chem., 44, 7329 (2020); https://doi.org/10.1039/C9NJ06052A
M.S. Alam, S. Rabi, M.M. Rahman, A. Baidya, M. Debi and T.G. Roy, J. Chem. Sci., 130, 35 (2018); https://doi.org/10.1007/s12039-018-1438-z
T.G. Roy, S.K.S. Hazari, B.K. Dey, H.A. Miah and E.R.T. Tiekink, Acta Crystallogr. Sect. E Struct. Rep. Online, 57, 524 (2001); https://doi.org/10.1107/S160053680100784X
C. Lap-Yan, E.C. Constable, M.S. Khan and J. Lewis, Inorg. Chim. Acta, 185, 93 (1991); https://doi.org/10.1016/S0020-1693(00)81681-3
V. Pawar, S. Joshi and V. Uma, Biokemistri, 23, 21 (2011).
S. Singh, H.S. Yadav, A.K. Yadava and D.P. Rao, J. Chem., 2013, 947325 (2013); https://doi.org/10.1155/2013/947325
S.N. Thakur, K.S. Yadav, N.P. Singh and H.S. Yadav, J. Iran. Chem. Soc., 5, 328 (2008); https://doi.org/10.1007/BF03246126
N. Raman, J.D. Raja and A. Sakthivel, J. Chil. Chem. Soc., 53, 1568 (2008).
N.F. Curtis, S.A. Swann, T.N. Waters and I.E. Maxwell, J. Am. Chem. Soc., 91, 4588 (1969); https://doi.org/10.1021/ja01044a068
R. Bembi, S. M. Sondhi, A. K. Singh, A. K. Jhanji, T. G. Roy, J.W. Lown and R.G. Ball, Bull. Chem. Soc. Jpn., 62, 3701 (1989); https://doi.org/10.1246/bcsj.62.3701
B.M. Sarhan, R.M. Rumez and H.A. Hassan, J. Pure Appl. Sci., 26, 178 (2013).
W.J. Geary, Coord. Chem. Rev., 7, 81 (1971); https://doi.org/10.1016/S0010-8545(00)80009-0
M.E. Farago and J.M. James, Inorg. Chem., 4, 1706 (1965); https://doi.org/10.1021/ic50034a007
A. Sabatini and I. Bertini, Inorg. Chem., 4, 959 (1965); https://doi.org/10.1021/ic50029a007
A.V. Iogansen and G.D. Litovchenko, J. Appl. Spectrosc., 2, 159 (1965); https://doi.org/10.1007/BF00655122
A.B.P. Lever, E. Mantovani and B.S. Ramaswamy, Can. J. Chem., 49, 1957 (1971); https://doi.org/10.1139/v71-315
F.B. Biswas, S. Saha and M.K. Ali, Asian Pac. J. Trop. Biomed., 4(Suppl. 2), 792 (2014); https://doi.org/10.12980/APJTB.4.2014C1298
