Ceratotheca sesamoides Endl.: Chemical Diversity and Potential for Bioactive Compounds in Modern Pharmacological Applications

D. Kabore; P. Sawadogo; A. Rama; R.E. Traore

doi:10.14233/ajchem.2025.34622

Issue

Vol. 37 No. 10 (2025): Vol 37 Issue 10, 2025

Issue Published : 30 September 2025

This work is licensed under a Creative Commons Attribution 4.0 International License.

Ceratotheca sesamoides Endl.: Chemical Diversity and Potential for Bioactive Compounds in Modern Pharmacological Applications

https://doi.org/10.14233/ajchem.2025.34622

D. Kabore

Laboratoire Biosciences, Équipe Génétique et Amélioration des Plantes, Université Joseph KI-ZERBO, Unité de Formation et de Recherche en Sciences de la Vie et de la Terre, 03 BP 7021 Ouagadougou 03, Burkina Faso

https://orcid.org/0000-0002-8232-3561

P. Sawadogo

https://orcid.org/0000-0001-8455-3179

A. Rama

https://orcid.org/0009-0003-4958-0106

R.E. Traore

https://orcid.org/0009-0001-0757-909X

Corresponding Author(s) : D. Kabore

dramanekabore61@gmail.com

Asian Journal of Chemistry, Vol. 37 No. 10 (2025): Vol 37 Issue 10, 2025
Article Published : 30 September 2025

Abstract

Ceratotheca sesamoides is a plant species having notable nutritional and medicinal properties, but it remains unexplored in West Africa, despite its importance in traditional agro-food systems. This study aimed to characterize the genetic, agromorphological and biochemical diversity of local accessions in Burkina Faso and propose sustainable valorization strategies for the species. Forty-nine samples were collected from different agro-ecological zones. Genetic diversity was analyzed using simple sequence repeat (SSR) markers, with data processed by GenAiEx version 6.501, revealing significant variation among accessions. Genetic structuring was examined using the Neighbor-Joining method, identifying three distinct genetic groups. Agromorphological, physico-chemical and biochemical diversity were assessed using statistical tools in R version 4.3.3. The analysis of variance indicated significant differences in traits between groups. Pearson correlation coefficients were computed to study the relationships between key bioactive compounds like polyphenols, flavonoids, alkaloids and essential minerals, such as magnesium, copper and sodium. These findings suggest substantial potential for the species in therapeutic and nutritional applications, supporting its sustainable valorization.

Keywords

Ceratotheca sesamoides Bioactive compounds Genetic diversity Sustainable valorization

(1)

Kabore, D.; Sawadogo, P.; Rama, A.; Traore, R. Ceratotheca Sesamoides Endl.: Chemical Diversity and Potential for Bioactive Compounds in Modern Pharmacological Applications. ajc 2025, 37, 2507-2513.

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Z. Li, L. Yun, Z. Gao, T. Wang, X. Ren and Y. Zhao, Front. Plant Sci., 13, 837787 (2022); https://doi.org/10.3389/fpls.2022.837787

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J. Yamoah, Int. J. Pharm. Sci. Med., 2, 82 (2024); https://doi.org/10.70199/IJPSM.2.3.82-88

J.M. Hancock, J. Mol. Evol., 41, (1995); https://doi.org/10.1007/BF00173185

L. Zhang, Z. Zhang and L. Gao, Appl. Plant Sci., 1, 1200235 (2013); https://doi.org/10.3732/apps.1200235

A.M. Bautista Salas, Ph.D. Thesis, Caractérisation Agro-morphologique d’une Collection de Landraces Péruviennes de Pigeonpea (Cajanus cajan L. Millsp.) Pour l’analyse de sa Diversité, University of Namur, Namur, Belgium (2009) (In French).

Z. Liu, M. Zhao, H. Zhang, T. Ren, C. Liu and N. He, Glob. Change Biol., 29, 1144 (2023); https://doi.org/10.1111/gcb.16518

S. Nakra, S. Tripathy and P.P. Srivastav, Phytomed. Plus, 5, 100762 (2025); https://doi.org/10.1016/j.phyplu.2025.100762

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G.D. Sadler and P.A. Murphy, eds.: S.S. Nielsen, pH and Titratable Acidity; In: Food Analysis Springer USA, pp. 219-238 (2010).

L. Zhang, D.-W. Sun and Z. Zhang, Crit. Rev. Food Sci. Nutr., 57, 1052 (2017); https://doi.org/10.1080/10408398.2015.1108282

S. Letchuman, H.D.T. Madhuranga, B.L.N.K. Madhurangi, A.D. Premarathna and M. Saravanan. Intelligent Pharm., 3, 268 (2025); https://doi.org/10.1016/j.ipha.2024.09.007

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D. Roze and N.H. Barton, Genetics, 173, 1793 (2006); https://doi.org/10.1534/genetics.106.058586

W.P. Monteiro, J. Dalapicolla, C.S. Carvalho, J. Costa-Veiga, S.J. Ramos, S. Vasconcelos, M. Gastauer, R. Jaffé and C.F. Caldeira, Conserv. Genet., 23, 745 (2022); https://doi.org/10.1007/s10592-022-01454-6

M.M. Alami, S. Guo, Z. Mei, G. Yang and X. Wang, Med. Plant Biol., 3, e016 (2024); https://doi.org/10.48130/mpb-0024-0016

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W. Yu, Y. Zhang, Y. Lu, Z. Ouyang, J. Peng, Y. Tu and B. He, J. Funct. Foods, 124, 106627 (2025); https://doi.org/10.1016/j.jff.2024.106627

P.J. White and P.H. Brown, Ann. Bot., 105, 1073 (2010); https://doi.org/10.1093/aob/mcq085

J. Koricheva and K.E. Barton, eds.: G.R. Iason, M. Dicke and S.E. Hartley, Temporal Changes in Plant Secondary Metabolite Production: Patterns, Causes and Consequences, In: The Ecology of Plant Secondary Metabolites, Cambridge University Press, edn. 1, pp. 34-55 (2012).

H. Zandavar and M.A. Babazad, eds.: E. Ivanišová, Secondary Metabolites: Alkaloids and Flavonoids in Medicinal Plants, In: Herbs and Spices: New Advances. IntechOpen (2023).

M. Sarraf, E. Janeeshma, N. Arif, M. Qudrat Ullah Farooqi, V. Kumar, N.A. Ansari, M.I. Ghani, M.A. Ahanger and M. Hasanuzzaman, Plant Stress, 10, 100224 (2023); https://doi.org/10.1016/j.stress.2023.100224

P. Marschner, Marschner’s Mineral Nutrition of Higher Plants, Academic Press (2012).

Author biographies is not available.