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Vol. 26 No. 21 (2014): Vol 26 Issue 21

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Phase Transfer Catalyzed Synthesis and Biological Activity of Thiourea Derivatives Containing 1,2,3-Thiadiazole Moiety

https://doi.org/10.14233/ajchem.2014.17152
Li-Jing Min
College of Life Sciences, Huzhou Teachers College, Huzhou 313000, Zhejiang, P.R. China
Ming-Yan Yang
College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, P.R. China
Zhao-Hui Sun
College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, P.R. China
Cheng-Xia Tan
College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, P.R. China
Jian-Quan Weng
College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, P.R. China
Hong-Ke Wu
College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, P.R. China
Xing-Hai Liu
College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, P.R. China

Corresponding Author(s) : Xing-Hai Liu

xhliu@zjut.edu.cn

Asian Journal of Chemistry, Vol. 26 No. 21 (2014): Vol 26 Issue 21

Abstract

A series of N-(substituted-phenyl)-N'-(4-methyl-1,2,3-thiadiazole-5-yl)-thiourea (7a-7e) were
synthesized and characterized. The chemical structures of all the compounds were confirmed
by 1H NMR, MS and elemental analysis. All the compounds were investigated for fungicidal
activity and plant growth regulatory activity. The bioassay results indicated that some of these
compound exhibit moderate fungicidal activities.

Keywords

Thiourea Synthesis Fungicidal activity 1,2,3-Thiadiazole Plant growth regulatory activity
Min, L.-J., Yang, M.-Y., Sun, Z.-H., Tan, C.-X., Weng, J.-Q., Wu, H.-K., & Liu, X.-H. (2014). Phase Transfer Catalyzed Synthesis and Biological Activity of Thiourea Derivatives Containing 1,2,3-Thiadiazole Moiety. Asian Journal of Chemistry, 26(21), 7413–7415. https://doi.org/10.14233/ajchem.2014.17152
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