Issue

Vol. 36 No. 9 (2024): Vol 36 Issue 9, 2024

Copyright (c) 2024 Anahas Perianaika Matharasi Antonyraj, Yuvarani Muthusamy, Kiruthika S, Shiyamala G, Ashokkumar L, Prasannabalaji Nainangu

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Mycosynthesis and Characterization of Zinc Oxide Nanoparticles from Shiitake Mushrooms (Lentinula edodes): Potential Antidiabetic, Antimicrobial and Antioxidant Efficacy

https://doi.org/10.14233/ajchem.2024.32363
M. Yuvarani
Department of Microbiology, Vivekanandha College of Arts and Sciences for Women, Tiruchengode-637205, India
https://orcid.org/0000-0002-9573-3957
S. Kiruthika
Department of Microbiology, Vivekanandha College of Arts and Sciences for Women, Tiruchengode-637205, India
https://orcid.org/0009-0005-6958-6315
G. Shiyamala
Department of Microbiology, Vivekanandha College of Arts and Sciences for Women, Tiruchengode-637205, India
https://orcid.org/0000-0001-8089-7628
L. Ashokkumar
Department of Microbiology, Vivekanandha College of Arts and Sciences for Women, Tiruchengode-637205, India
https://orcid.org/0000-0003-2616-4751
N. Prasannabalaji
PG & Research Department of Microbiology, Sri Sankara Arts and Science College, Kanchipuram-631561, India
https://orcid.org/0000-0001-6212-2829
A. Anahas Perianaika Matharasi
Department of Research Analytics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Poonamallee, Chennai-600077, India
https://orcid.org/0000-0003-4429-8104

Corresponding Author(s) : A. Anahas Perianaika Matharasi

anahas.arasi@gmail.com

Asian Journal of Chemistry, Vol. 36 No. 9 (2024): Vol 36 Issue 9, 2024

Abstract

Zinc oxide nanoparticles (ZnO NPs) are widely used because they are affordable, reliable and easy to produce. They have special characteristics which render them useful in different medicines. Due to their health benefits, affordability and minimal impact on the environment, mushrooms are a highly favourable option for biomedical applications. In this study, we used a water-soluble component of a methanolic extract of Lentinula edodes to produce ZnO NPs. The biosynthetic approach utilized flavonoids, polyphenols and other constituents from L. edodes, which possess reduction and encapsulation capabilities, to transform metal ions into ZnO NPs. Various analytical methods, including UV-Vis, FTIR and SEM, have been used to characterize the biogenic ZnO NPs. The FTIR analysis identified the presence of the hydroxyl (OH) group based on the functional group observed at 3425.08 cm–1, moreover, the peaks observed at 1631.32 cm–1 indicated the presence of C=O carboxylic stretch bonds. Scanning electron microscopy (SEM) demonstrated the presence of a porous shape with diameters of 35-200 nm. The biologically produced ZnO NPs showed promising antibacterial, antioxidant and antidiabetic properties. At specific concentrations, it showed strong antioxidant (70.51 ± 0.35%) and antidiabetic (82.36 ± 0.41%) effects, indicating that it could be used therapeutically for the treatment of diabetic conditions and could be suitable for incorporation into food and nutritional supplements.

Keywords

Zinc nanoparticles Lentinula edodes Antioxidant activity Antidiabetic activity Mushroom
Yuvarani, M., Kiruthika, S., Shiyamala, G., Ashokkumar, L., Prasannabalaji, N., & Matharasi, A. A. P. (2024). Mycosynthesis and Characterization of Zinc Oxide Nanoparticles from Shiitake Mushrooms (Lentinula edodes): Potential Antidiabetic, Antimicrobial and Antioxidant Efficacy. Asian Journal of Chemistry, 36(9), 2191–2196. https://doi.org/10.14233/ajchem.2024.32363
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. S. Dey, D.L. Mohanty, N. Divya, V. Bakshi, A. Mohanty, D. Rath, S. Das, A. Mondal, S. Roy and R. Sabui, Intelligent Pharm., (2024); https://doi.org/10.1016/j.ipha.2024.08.004
  2. S. Raha and M. Ahmaruzzaman, Nanoscale Adv., 4, 1868 (2022); https://doi.org/10.1039/D1NA00880C
  3. S. Jha, R. Rani and S. Singh, J. Inorg. Organomet. Polym., 33, 1437 (2023); https://doi.org/10.1007/s10904-023-02550-x
  4. X.Q. Zhou, Z. Hayat, D.D. Zhang, M.Y. Li, S. Hu, Q. Wu, Y.F. Cao and Y. Yuan, Processes, 11, 1193 (2023); https://doi.org/10.3390/pr11041193
  5. K.A. Altammar, Front. Microbiol., 14, 1155622 (2023); https://doi.org/10.3389/fmicb.2023.1155622
  6. S. Jha, R. Rani and S. Singh, J. Inorg. Organomet. Polym. Mater., 33, 1437 (2023); https://doi.org/10.1007/s10904-023-02550-x
  7. C.M. Rafeeq, E. Paul, E.V. Saagar and P.M. Ali, Ceram. Int., 47, 12375 (2021); https://doi.org/10.1016/j.ceramint.2021.01.091
  8. S. Sudheer, R.G. Bai, K. Muthoosamy, R. Tuvikene, V.K. Gupta and S. Manickam, Environ. Res., 204, 111963 (2022); https://doi.org/10.1016/j.envres.2021.111963
  9. A.B. Moghaddam, F. Namvar, M. Moniri, P.M. Tahir, S. Azizi and R. Mohamad, Molecules, 20, 16540 (2015); https://doi.org/10.3390/molecules200916540
  10. N.A. Tijani, J. Hokello, K.O. Awojobi, R. Marnadu, M. Shkir, Z. Ahmad, A.O. Afolabi, S.A. Adewinbi and I.A. Adebayo, J. Drug Deliv. Sci. Technol., 96, 105695 (2024); https://doi.org/10.1016/j.jddst.2024.105695
  11. U. Ejaz, M. Afzal, M. Naveed, Z.S. Amin, A. Atta, T. Aziz, G. Kainat, N. Mehmood, M. Alharbi and A.F. Alasmari, Sci. Rep., 14, 5751 (2024); https://doi.org/10.1038/s41598-024-56421-7
  12. Y. Zhou, M. Chu, F. Ahmadi, O.T. Agar, C.J. Barrow, F.R. Dunshea and H.A. Suleria, Food Rev. Int., 40, 924 (2024); https://doi.org/10.1080/87559129.2023.2202738
  13. M. Ziaja-Soltys, W. Radzki, J. Nowak, J. Topolska, E. Jablonska-Rys, A. Slawinska, K. Skrzypczak, A. Kuczumow and A. Bogucka-Kocka, Appl. Sci., 10, 470 (2020); https://doi.org/10.3390/app10020470
  14. M.A. Rahman, N. Abdullah and N. Aminudin, Saudi J. Biol. Sci., 25, 1515 (2018); https://doi.org/10.1016/j.sjbs.2016.01.021
  15. S.M. Gharibzahedi, M. Moghadam, J. Amft, A. Tolun, G. Hasabnis and Z. Altintas, Molecules, 28, 7469 (2023); https://doi.org/10.3390/molecules28227469
  16. A.I. Osman, Y. Zhang, M. Farghali, A.K. Rashwan, A.S. Eltaweil, E.M. Abd El-Monaem, I.M. Mohamed, M.M. Badr, I. Ihara, D.W. Rooney and P.S. Yap, Environ. Chem. Lett., 22, 841 (2024); https://doi.org/10.1007/s10311-023-01682-3
  17. Z.A. Gadoa, A.H. Moustafa, S.M. El Rayes, A.A. Arisha and M.F. Mansour, ACS Omega, 7, 36865 (2022); https://doi.org/10.1021/acsomega.2c05638
  18. J. Kaur, H. Farooqi, K. Chandra and B.P. Panda, Heliyon, 10, e27363 (2024); https://doi.org/10.1016/j.heliyon.2024.e27363
  19. Y.A. Selim, M.A. Azb, I. Ragab and H.M. Abd El-Azim, Sci. Rep., 10, 3445 (2020); https://doi.org/10.1038/s41598-020-60541-1
  20. N.M. Ngoepe, Z. Mbita, M. Mathipa, N. Mketo, B. Ntsendwana and N.C. Hintsho-Mbita, Ceram. Int., 44, 16999 (2018); https://doi.org/10.1016/j.ceramint.2018.06.142
  21. M. Anbuvannan, M. Ramesh, G. Viruthagiri, N. Shanmugam and N. Kannadasan, Spectrochim. Acta A Mol. Biomol. Spectrosc., 143, 304 (2015); https://doi.org/10.1016/j.saa.2015.01.124
  22. R.D. Fernandes, M.A. Trindade, F.G. Tonin, C.G. Lima, S.M. Pugine, P.E. Munekata, J.M. Lorenzo and M.P. De Melo, J. Food Sci. Technol., 53, 451 (2016); https://doi.org/10.1007/s13197-015-1994-x
  23. P. Nainangu, S.N. Mothilal, K. Subramanian, M. Thanigaimalai, R. Kandasamy, G.P. Srinivasan, S. Gopal, M.R. Shaik, Z.A. Kari, A. Guru and A.P. Antonyraj, Mol. Biol. Rep., 51, 730 (2024); https://doi.org/10.1007/s11033-024-09666-4
  24. G. Karunakaran, K.G. Sudha, S. Ali and E.B. Cho, Molecules, 28, 4527 (2023); https://doi.org/10.3390/molecules28114527
  25. Z.S. Amin, M. Afzal, J. Ahmad, N. Ahmed, B. Zeshan, N.H. Hashim and C.Y. Yean, Molecules, 28, 3532 (2023); https://doi.org/10.3390/molecules28083532
  26. A.S. Abdelbaky, T.A. Abd El-Mageed, A.O. Babalghith, S. Selim and A.M. Mohamed, Antioxidants, 11, 1444 (2022); https://doi.org/10.3390/antiox11081444
  27. J.Z. Tayyeb, M. Priya, A. Guru, M.S. Kishore Kumar, J. Giri, A. Garg, R. Agrawal, K.B. Mat and J. Arockiaraj, Mol. Biol. Rep., 51, 423 (2024); https://doi.org/10.1007/s11033-024-09407-7
  28. O.V. Ravikumar, V. Marunganathan, M.S. Kumar, M. Mohan, M.R. Shaik, B. Shaik, A. Guru and K. Mat, Mol. Biol. Rep., 51, 352 (2024); https://doi.org/10.1007/s11033-024-09289-9
Read More
Author biographies is not available.
Statistic
Read Counter : 0 Download : 0