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Vol. 36 No. 1 (2024): Vol 36 Issue 1, 2024

Copyright (c) 2023 Jayaprakash Rajendran, Ezhilarasu .D, S. Rani

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Ultrasound and Two Active Site Phase-Transfer Catalyst Effect in Asymmetry Synthesis: A Kinetic Study

https://doi.org/10.14233/ajchem.2024.30695
D. Ezhilarasu
PG and Research Department of Chemistry, Arignar Anna Government Arts College, Cheyyar- 604407, Tamilnadu, INDIA;bDepartment of Chemistry, P.T. Lee. Chengalvaraya Naicker College of Engineering & Technology, Oovery, Veliyur, Kanchipuram-631502, Tamilnadu-India
https://orcid.org/0009-0006-2047-1098
S. Rani
PG and Research Department of Chemistry, Arignar Anna Government Arts College, Cheyyar- 604407, Tamilnadu, INDIA
https://orcid.org/0000-0003-0074-8441
R. Jayaprakash
Department of Chemistry, School of Arts and Science, Vinayaka Mission’s Chennai Campus, Vinayaka Mission’s Research Foundation (Deemed University), Paiyanoor, Chennai-603104, India
https://orcid.org/0000-0002-4323-4910

Corresponding Author(s) : S. Rani

raniselvaraj1970@gmail.com

Asian Journal of Chemistry, Vol. 36 No. 1 (2024): Vol 36 Issue 1, 2024

Abstract

The phase transfer catalyst 1-benzyl-1,4-diazoniabicyclo[2.2.1]hepta-2,4(7)-dienedichloride (BDHDC) in organic chiral synthesis was used in this study. Kinetic parameters such as ultrasonication effect, phase transfer catalyst dose, solvents, butyl chloride volume, stirring speed and weight of KOH were examined for the phase transfer catalytic reactions. The reaction between phenyl acetonitrile  and butyl chloride was carried out under basic conditions and ultrasonic irradiation (300 W, 40 kHz) using BDHDC as a phase transfer  catalyst. The introduction of BDHDC catalyst significantly improved the overall reaction, resulting in a high yield of the chiral  combination. The product formation has been optimized by modifying the kinetic parameters. 

Keywords

substitution reaction phase transfer catalyst kinetic study
Ezhilarasu, D., S. Rani, & Jayaprakash, R. (2023). Ultrasound and Two Active Site Phase-Transfer Catalyst Effect in Asymmetry Synthesis: A Kinetic Study. Asian Journal of Chemistry, 36(1), 93–96. https://doi.org/10.14233/ajchem.2024.30695
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