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Vol. 36 No. 12 (2024): Vol 36 Issue 12, 2024

Copyright (c) 2024 Anil Athare

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Physico-Chemical, Phytochemical and Pharmacological Attributes of Caesalpinia crista L. Leaves

https://doi.org/10.14233/ajchem.2024.32685
Rajesh Valvi
Department of Chemistry, New Arts, Commerce and Science College, Shevgaon-414502, India
https://orcid.org/0000-0002-6704-6113
Anil Athare
Department of Chemistry, New Arts, Commerce and Science College, Ahmednagar-414001 India
https://orcid.org/0009-0009-7480-5489
Sushama Takate
Department of Chemistry, New Arts, Commerce and Science College, Ahmednagar-414001 India
https://orcid.org/0000-0002-0025-5244

Corresponding Author(s) : Anil Athare

ltanilathare@gmail.com

Asian Journal of Chemistry, Vol. 36 No. 12 (2024): Vol 36 Issue 12, 2024

Abstract

The present study aims to evaluate the antioxidant and antimicrobial activities of Caesalpinia crista L. (CCL) leaves extracts, along with conducts physico-chemical and phytochemical analysis. Herein, the Soxhlet and maceration methods were used to extract CCL leaves with solvents of varying polarity. The obtained extracts showed similar extractive content in alcohol and water with minimal ash content. FT-IR and GC-MS techniques were used to identify the nature and composition of phytochemicals revealing eight key compounds in the methanol extract and one in the water extract. These compounds were characterized by alcohol, alkane, carbonyl and ether functional groups. The antioxidant activity was evaluated by quantifying total phenolic and flavonoid content and assessing radical scavenging activity, with results indicating that both methanol and water extracts exhibited nearly identical antioxidant activity. Antimicrobial activity was evaluated using the zone of inhibition method along with MIC measurements. The chloroform and methanol extracts exhibited antibacterial efficacy against E. coli, P. aeruginosa and S. aureus, while the methanol extract showed antifungal activity specifically against F. oxysporum. The findings suggest that the key phytochemicals are responsible for the observed antioxidant and antimicrobial activities. Furthermore, isolating these significant phytochemicals could lead to the development of potent drugs for various diseases in the future.

Keywords

Caesalpinia crista L. Antimicrobial activity Antioxidant activity Phytochemical analysis
Valvi, R., Athare, A., & Takate, S. (2024). Physico-Chemical, Phytochemical and Pharmacological Attributes of Caesalpinia crista L. Leaves. Asian Journal of Chemistry, 36(12), 2809–2816. https://doi.org/10.14233/ajchem.2024.32685
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